Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   DQM69_RS04570 Genome accession   NZ_LS483381
Coordinates   953655..955802 (-) Length   715 a.a.
NCBI ID   WP_021673784.1    Uniprot ID   U2KIX5
Organism   Streptococcus sobrinus strain NCTC10921     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 948655..960802
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM69_RS04545 - 949102..949628 (+) 527 Protein_850 YbaK/EbsC family protein -
  DQM69_RS04550 (NCTC10921_00894) - 950041..950544 (+) 504 WP_019777342.1 phosphatase PAP2 family protein -
  DQM69_RS04555 (NCTC10921_00895) - 950659..951402 (+) 744 WP_109982563.1 response regulator transcription factor -
  DQM69_RS04560 (NCTC10921_00896) - 951405..952751 (+) 1347 WP_002998464.1 sensor histidine kinase -
  DQM69_RS04565 (NCTC10921_00897) - 952869..953642 (-) 774 WP_019770708.1 HlyD family efflux transporter periplasmic adaptor subunit -
  DQM69_RS04570 (NCTC10921_00898) comA/nlmT 953655..955802 (-) 2148 WP_021673784.1 peptide cleavage/export ABC transporter Regulator
  DQM69_RS04575 (NCTC10921_00899) - 956116..956310 (+) 195 WP_019771729.1 bacteriocin class II family protein -
  DQM69_RS04580 (NCTC10921_00900) - 956367..956558 (+) 192 WP_019770705.1 Blp family class II bacteriocin -
  DQM69_RS04585 (NCTC10921_00901) - 956586..956771 (+) 186 WP_019770704.1 hypothetical protein -
  DQM69_RS04590 - 957021..958177 (-) 1157 Protein_859 IS256 family transposase -
  DQM69_RS04595 - 958478..958621 (+) 144 WP_019768643.1 hypothetical protein -
  DQM69_RS04600 (NCTC10921_00905) - 958653..959057 (+) 405 WP_109982564.1 hypothetical protein -
  DQM69_RS04605 (NCTC10921_00906) - 959107..960141 (+) 1035 WP_032672939.1 thioredoxin family protein -

Sequence

Protein


Download         Length: 715 a.a.        Molecular weight: 80357.42 Da        Isoelectric Point: 8.1599

>NTDB_id=1139395 DQM69_RS04570 WP_021673784.1 953655..955802(-) (comA/nlmT) [Streptococcus sobrinus strain NCTC10921]
MNFYKFVPQIDARDCGVAALASIARHYGANYSLAHLRELAKTDKEGTTALGIVEAAQTMGFETRAVRADMSLFEEEEIPY
PFIAHVNKEGKLQHYYVVYKAKKNHLIIGDPDPSVKVTKMSKERFEQEWDGISIFLAPEPAYKPHKDKKNGLLSFIPIIL
KQKGLIFQISLASLLVTLIDILGSYYLQGILDSYIPNQMTSTLTIVSLGLVITYVIQQIMAFSRDYLLTVLSQRLSIDVI
LAYIRHIFSLPMSFFATRRTGEITSRFSDANSIIDALASTILSIFLDCFILIIIGAVLLLQNANLFLLTLLSIPIYTIII
LAFMKPFEKMNQDVMEANSMVSSAIIEDINGMETIKSLTSEDTRYRNVDNEFVDYLDKSFKRHKYEILQTSLKKGAQLIL
NVAILWFGSTLVMVNKISIGQLVAYNSLLTYFTNPLENIINLQTKLQSAKVANNRLNEVYLVSSEFDQKTTKVNQEAPSG
DIVFSDVSYKYGFGRDTLTDINLKIAKGSKISLVGISGSGKTTLAKLIVNFFQPYKGEITIKSLNTNLLDKRLLRKYINY
LPQQPYVFSGSILENLTLGADESVSQEDIMKACEMAEIRRDIEQMPLGYQTELSDGAGLSGGQKQRIALARALLTKSPIM
VLDEATSGLDVLTEKKVIDNLMKMTEKTIIFVAHRLSISERTDKIVVLDQGRIIETGSHQDLLKKQGFYYQLFNK

Nucleotide


Download         Length: 2148 bp        

>NTDB_id=1139395 DQM69_RS04570 WP_021673784.1 953655..955802(-) (comA/nlmT) [Streptococcus sobrinus strain NCTC10921]
ATGAATTTTTACAAATTTGTTCCTCAGATTGATGCCAGAGACTGTGGAGTTGCTGCTCTCGCTTCTATCGCCCGTCATTA
CGGAGCAAACTATTCTTTAGCCCATTTGCGTGAACTGGCCAAGACGGATAAGGAGGGGACAACAGCTTTGGGTATTGTGG
AAGCTGCCCAGACCATGGGCTTTGAGACTCGGGCTGTCCGAGCTGATATGAGCCTTTTTGAAGAAGAGGAGATTCCCTAT
CCCTTTATCGCTCATGTCAATAAAGAGGGTAAACTACAACACTACTATGTAGTTTATAAGGCTAAGAAAAATCATCTGAT
TATCGGCGATCCCGATCCAAGTGTCAAAGTAACCAAGATGAGTAAAGAAAGATTTGAACAAGAATGGGATGGTATTTCCA
TTTTCCTAGCTCCAGAGCCAGCCTACAAACCCCATAAGGATAAGAAAAATGGTCTATTGAGTTTCATCCCAATCATTCTC
AAGCAAAAGGGGCTTATCTTCCAGATTAGTTTGGCCAGCCTTTTAGTGACCTTGATTGATATCTTGGGCTCCTACTACTT
ACAAGGGATTCTAGATAGTTATATTCCCAATCAAATGACTTCAACCTTGACCATTGTCTCGCTCGGTCTGGTCATTACCT
ATGTTATTCAGCAAATTATGGCCTTCTCACGGGACTATCTCTTAACAGTTCTCAGTCAGAGGCTCAGTATTGATGTGATC
CTGGCTTATATCCGTCATATCTTTTCCTTGCCCATGTCTTTCTTTGCGACAAGGCGAACGGGGGAGATTACCTCACGTTT
TTCAGATGCCAATTCTATCATTGATGCTCTGGCCTCAACTATTTTGTCCATCTTCTTAGATTGTTTTATTTTAATTATTA
TCGGAGCTGTTCTGCTTCTGCAAAACGCCAATCTCTTCCTCCTAACTTTGCTGTCTATCCCAATCTACACAATTATCATC
CTTGCCTTTATGAAACCCTTTGAAAAAATGAACCAAGATGTCATGGAAGCCAACAGTATGGTTAGCTCTGCTATCATTGA
AGATATCAACGGGATGGAAACCATCAAGTCGCTGACTAGTGAGGATACTCGCTACCGCAATGTTGATAATGAGTTTGTTG
ATTATCTAGATAAGTCCTTTAAACGCCACAAGTACGAAATTTTACAAACTTCCCTTAAAAAGGGAGCCCAGCTGATTTTA
AATGTCGCCATCCTCTGGTTTGGCTCAACACTGGTTATGGTCAATAAGATCTCCATTGGTCAACTCGTTGCCTATAATTC
TCTCTTAACCTACTTTACCAATCCGCTGGAAAACATCATCAACTTACAAACCAAGCTGCAATCGGCCAAAGTAGCCAATA
ATCGGCTCAATGAAGTTTACCTTGTTTCCTCGGAATTCGACCAGAAAACTACGAAAGTTAATCAAGAGGCTCCGTCTGGA
GATATTGTCTTTTCTGATGTCTCCTACAAATACGGGTTCGGTCGAGATACCCTGACCGACATTAACCTTAAAATTGCCAA
AGGTTCGAAAATCAGCTTGGTCGGTATCAGTGGCTCTGGGAAAACGACGCTGGCTAAACTGATTGTCAACTTTTTCCAAC
CCTACAAGGGAGAAATCACTATTAAGAGCCTAAATACCAACCTTTTGGATAAAAGGCTTCTTCGCAAATATATCAACTAC
CTACCTCAGCAACCTTATGTCTTTTCCGGAAGCATCTTAGAAAATTTGACTTTAGGTGCCGACGAGTCTGTCAGTCAAGA
GGACATCATGAAAGCCTGTGAGATGGCTGAAATCAGAAGAGATATCGAGCAAATGCCACTGGGTTATCAAACTGAGCTAT
CCGATGGGGCGGGACTCTCAGGTGGTCAAAAACAAAGGATAGCTCTGGCACGTGCCCTCCTGACAAAGTCACCGATTATG
GTCTTAGACGAAGCGACTAGCGGGCTAGATGTCTTAACAGAAAAAAAGGTCATTGACAACCTGATGAAGATGACCGAGAA
AACCATTATTTTTGTGGCCCACCGACTCAGCATTTCTGAGCGGACTGACAAAATTGTTGTTCTTGACCAGGGAAGAATTA
TTGAAACAGGTTCCCATCAGGATTTGCTTAAAAAGCAAGGCTTCTACTACCAACTTTTTAATAAATAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(4-140)

ABC transporter transmembrane region (ABC_membrane)

(170-436)

ABC transporter (ABC_tran)

(498-647)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U2KIX5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

70.464

99.441

0.701
  comA Streptococcus mitis NCTC 12261

65.83

100

0.66
  comA Streptococcus mitis SK321

65.551

100

0.657
  comA Streptococcus pneumoniae TIGR4

65.272

100

0.655
  comA Streptococcus pneumoniae R6

65.272

100

0.655
  comA Streptococcus pneumoniae Rx1

65.272

100

0.655
  comA Streptococcus pneumoniae D39

65.272

100

0.655
  comA Streptococcus gordonii str. Challis substr. CH1

65.132

100

0.653

Multiple sequence alignment