Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DQM75_RS08615 Genome accession   NZ_LS483380
Coordinates   1797955..1798719 (-) Length   254 a.a.
NCBI ID   WP_111692765.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC11824     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1792955..1803719
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM75_RS08595 (NCTC11824_01728) - 1793287..1794513 (-) 1227 WP_014623468.1 cysteine desulfurase -
  DQM75_RS08600 (NCTC11824_01729) sufD 1794540..1795802 (-) 1263 WP_111692764.1 Fe-S cluster assembly protein SufD -
  DQM75_RS08605 (NCTC11824_01730) sufC 1795894..1796664 (-) 771 WP_043031422.1 Fe-S cluster assembly ATPase SufC -
  DQM75_RS08610 (NCTC11824_01731) - 1796791..1797948 (-) 1158 WP_111692939.1 glycosyltransferase family 4 protein -
  DQM75_RS08615 (NCTC11824_01732) mecA 1797955..1798719 (-) 765 WP_111692765.1 adaptor protein MecA Regulator
  DQM75_RS08620 (NCTC11824_01733) - 1798839..1799678 (-) 840 WP_014623473.1 undecaprenyl-diphosphate phosphatase -
  DQM75_RS08625 (NCTC11824_01734) - 1799994..1801562 (+) 1569 WP_111692766.1 ABC transporter substrate-binding protein/permease -
  DQM75_RS08630 (NCTC11824_01735) - 1801555..1802295 (+) 741 WP_014623475.1 amino acid ABC transporter ATP-binding protein -
  DQM75_RS08635 (NCTC11824_01736) - 1802642..1802758 (+) 117 WP_012677375.1 putative metal homeostasis protein -

Sequence

Protein


Download         Length: 254 a.a.        Molecular weight: 29289.15 Da        Isoelectric Point: 4.2566

>NTDB_id=1139360 DQM75_RS08615 WP_111692765.1 1797955..1798719(-) (mecA) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
MEMKQISETTLKITIGMDDLEERGMELKDFLIPQEKTEEFFYAVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDL
NKDLNFEDLADLGDISQMTPEDFFRSLEQSMREKGDVNAHEKLEKIEEIMEDVVDATLAEQADSKEAAELDEPTEPLDYV
HYVLDFASVRDAVCFAKVIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARLIEHARPGTKTRAYLQEHGCQLI
FDGAVEELQKIRLG

Nucleotide


Download         Length: 765 bp        

>NTDB_id=1139360 DQM75_RS08615 WP_111692765.1 1797955..1798719(-) (mecA) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTGGTATGGACGATTTAGAAGAAAGGGGGATGGAGCT
CAAGGACTTCTTGATCCCTCAAGAAAAGACAGAGGAGTTCTTTTATGCTGTCATGGACGAGTTGGACCTTCCGGACAATT
TTAAGGACAGTGGTATGCTTAGCTTTCGAGTGACTCCAAGAAAGGATCGCTTAGATGTTTTTGTGACCAAATCAGACCTC
AATAAGGACCTTAATTTTGAGGATTTGGCAGACCTAGGTGATATTTCTCAAATGACTCCAGAGGATTTTTTCAGAAGCTT
GGAGCAGTCTATGCGTGAAAAGGGTGATGTCAATGCCCATGAAAAGCTTGAAAAAATCGAGGAGATCATGGAGGACGTGG
TTGATGCTACCTTGGCTGAGCAAGCAGATAGTAAGGAAGCTGCTGAGCTTGATGAGCCGACAGAGCCACTTGATTATGTT
CACTATGTTCTTGATTTTGCTTCTGTTCGAGACGCTGTTTGCTTTGCTAAGGTGATTGATTTTCCGATCGAGGCTTCTGA
ATTGTATAAGGGTCCTCGTCATTATCACATGACGATTTTACTTGATGTGCAAAACAAGCCTGCCTATTTTGCCAATGTGA
TGTATGCCAGATTGATTGAGCATGCTAGACCTGGTACAAAAACAAGAGCTTATTTGCAGGAGCATGGTTGTCAGCTCATT
TTTGATGGTGCTGTTGAGGAGCTGCAAAAAATCAGGTTGGGGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.347

98.819

0.626
  mecA Streptococcus thermophilus LMD-9

57.255

100

0.575
  mecA Streptococcus thermophilus LMG 18311

56.471

100

0.567
  mecA Streptococcus pneumoniae TIGR4

47.638

100

0.476
  mecA Streptococcus pneumoniae Rx1

47.244

100

0.472
  mecA Streptococcus pneumoniae D39

47.244

100

0.472
  mecA Streptococcus pneumoniae R6

47.244

100

0.472

Multiple sequence alignment