Detailed information NTG1139334

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: DQM75_RS04640
• Genome accession: NZ_LS483380
• Coordinates: 975673..976347 (+)
• Length: 224 a.a.
• NCBI ID: WP_021320708.1
• Uniprot ID: A0AAW3GMV5
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC11824
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 970673..981347

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM75_RS04625 (NCTC11824_00925)	pstB	971000..971758 (+)	759	WP_012678019.1	phosphate ABC transporter ATP-binding protein PstB	-
DQM75_RS04630 (NCTC11824_00926)	phoU	971829..972482 (+)	654	WP_012678018.1	phosphate signaling complex protein PhoU	-
DQM75_RS04635 (NCTC11824_00927)	-	972717..975254 (+)	2538	WP_043052123.1	M1 family metallopeptidase	-
DQM75_RS04640 (NCTC11824_00928)	ciaR	975673..976347 (+)	675	WP_021320708.1	response regulator transcription factor	Regulator
DQM75_RS04645 (NCTC11824_00929)	ciaH	976340..977650 (+)	1311	WP_012515549.1	sensor histidine kinase	Regulator
DQM75_RS04650 (NCTC11824_00930)	-	978035..978469 (+)	435	WP_012678015.1	hypothetical protein	-
DQM75_RS10055 (NCTC11824_00931)	-	978551..978727 (+)	177	WP_337660729.1	hypothetical protein	-
DQM75_RS04655 (NCTC11824_00932)	-	978743..979150 (+)	408	WP_014622815.1	hypothetical protein	-
DQM75_RS04660 (NCTC11824_00933)	-	979160..979450 (+)	291	WP_021320713.1	hypothetical protein	-
DQM75_RS04665 (NCTC11824_00934)	-	979374..979757 (+)	384	WP_012678013.1	hypothetical protein	-
DQM75_RS04670 (NCTC11824_00935)	-	979759..980010 (+)	252	WP_012678012.1	hypothetical protein	-
DQM75_RS04675 (NCTC11824_00936)	-	980186..980566 (+)	381	WP_042670594.1	hypothetical protein	-
DQM75_RS04680 (NCTC11824_00937)	-	980563..980823 (+)	261	WP_021320716.1	hypothetical protein	-
DQM75_RS04685 (NCTC11824_00938)	-	980839..981252 (+)	414	WP_037584321.1	hypothetical protein	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25569.58 Da
• Isoelectric Point: 4.5644

>NTDB_id=1139334 DQM75_RS04640 WP_021320708.1 975673..976347(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTA
KESIDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQVIELLGKELDLLIY
ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGYILKANE

Nucleotide

• Length: 675 bp

>NTDB_id=1139334 DQM75_RS04640 WP_021320708.1 975673..976347(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
ATGATAAAACTATTATTAGTAGAAGACGATTTAAGCTTATCAAATTCCATCTTTGATTTTTTAGATGACTTTGCTGATGT
GACCCAGGTTTTTGATGGCGACGAAGGACTCTATGAGGCAGAAAGCGGCATTTATGATTTGATTCTGTTAGATTTGATGC
TGCCTGAAAAGGATGGCTTTCAAGTGCTAAAGGCCTTACGTGAAAAAGACATCAAAATTCCCGTCTTGATCATGACTGCC
AAAGAAAGCATTGATGACAAGGGACATGGCTTTGAGCTTGGTGCTGATGACTATTTAACCAAGCCCTTTTACCTAGAGGA
ATTAAAAATGCGGATTCAGGCCTTGCTTAAGCGCGTAGGAAAGTTTAATGATAAGAGCCTTAAATTTGGCAACCTGACTG
TAGATACTACCCGTAAAGAGGTACAGGTCAATGGGCAGGTCATAGAGCTATTAGGCAAGGAGCTTGATTTACTAATCTAT
ATCCTTCAAAATCAAAATGTTATTTTGCCAAAGTCACAAATTTTTGATCGTATCTGGGGCTTTGATAGTGATACCACTAT
CTCTGTTGTAGAGGTCTATGTCTCTAAAATCCGTAAGAAGCTTAAGGGGACAGACTTTGTTAATCATCTTCAAACCTTGA
GAAGTGTAGGATATATCTTAAAAGCTAATGAATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (5-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	84.615	98.661	0.835
ciaR	Streptococcus pneumoniae Rx1	80.543	98.661	0.795
ciaR	Streptococcus pneumoniae D39	80.543	98.661	0.795
ciaR	Streptococcus pneumoniae R6	80.543	98.661	0.795
ciaR	Streptococcus pneumoniae TIGR4	80.543	98.661	0.795
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.865	100	0.397