Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   DQM75_RS04645 Genome accession   NZ_LS483380
Coordinates   976340..977650 (+) Length   436 a.a.
NCBI ID   WP_012515549.1    Uniprot ID   A0AAW3GN95
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC11824     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 971340..982650
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM75_RS04630 (NCTC11824_00926) phoU 971829..972482 (+) 654 WP_012678018.1 phosphate signaling complex protein PhoU -
  DQM75_RS04635 (NCTC11824_00927) - 972717..975254 (+) 2538 WP_043052123.1 M1 family metallopeptidase -
  DQM75_RS04640 (NCTC11824_00928) ciaR 975673..976347 (+) 675 WP_021320708.1 response regulator transcription factor Regulator
  DQM75_RS04645 (NCTC11824_00929) ciaH 976340..977650 (+) 1311 WP_012515549.1 sensor histidine kinase Regulator
  DQM75_RS04650 (NCTC11824_00930) - 978035..978469 (+) 435 WP_012678015.1 hypothetical protein -
  DQM75_RS10055 (NCTC11824_00931) - 978551..978727 (+) 177 WP_337660729.1 hypothetical protein -
  DQM75_RS04655 (NCTC11824_00932) - 978743..979150 (+) 408 WP_014622815.1 hypothetical protein -
  DQM75_RS04660 (NCTC11824_00933) - 979160..979450 (+) 291 WP_021320713.1 hypothetical protein -
  DQM75_RS04665 (NCTC11824_00934) - 979374..979757 (+) 384 WP_012678013.1 hypothetical protein -
  DQM75_RS04670 (NCTC11824_00935) - 979759..980010 (+) 252 WP_012678012.1 hypothetical protein -
  DQM75_RS04675 (NCTC11824_00936) - 980186..980566 (+) 381 WP_042670594.1 hypothetical protein -
  DQM75_RS04680 (NCTC11824_00937) - 980563..980823 (+) 261 WP_021320716.1 hypothetical protein -
  DQM75_RS04685 (NCTC11824_00938) - 980839..981252 (+) 414 WP_037584321.1 hypothetical protein -
  DQM75_RS04690 (NCTC11824_00939) - 981253..982446 (+) 1194 WP_024273226.1 lipase -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49574.22 Da        Isoelectric Point: 9.6507

>NTDB_id=1139335 DQM75_RS04645 WP_012515549.1 976340..977650(+) (ciaH) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
MNKLKKGLLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYSTVDSSLISVGQNASNYANRTMARISSFYFDAENNLI
QALPELEASKSLGSSTTNMDIILFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILDNSEHIASSLDEVRNMRILTTNLLNLARRDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISAN
QINRPLKTDKALLKQLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVDKARTRQKG
GFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=1139335 DQM75_RS04645 WP_012515549.1 976340..977650(+) (ciaH) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
ATGAATAAACTAAAAAAAGGATTATTGTCCGATAATTATACGCATTTTTTTCATTTCTTTGCTATTTTTACAGGCATTTT
TGTTGTCATGACCATCATTATTTTGCAAATCATGAGGTTTAGTGTCTATTCCACAGTAGACAGCAGTCTCATTTCGGTCG
GTCAAAATGCCAGTAACTATGCCAATAGGACCATGGCGAGAATATCTTCCTTTTATTTTGATGCAGAAAATAACCTTATT
CAGGCTCTTCCTGAACTGGAAGCGTCAAAATCACTTGGCTCCTCCACCACTAATATGGATATTATTTTATTTAGTGCTAA
TGGGACGATATTGAACTCCTTTGACGCTTTCTCTAATTACCAAAGCTTTCGTTTAGACAAAAGCCAGCTCAATAACATTG
TCACAACACAGCTGATGAATTTTTATGGGCAAAAGGAGAAATACCATACCCTAACTGTTAAGGTTCACATTAAAAACTAT
CCAGCAGTGGCTTATATGATGGCAGTGGTTAATGTTCAGCAGTTGGATACTGCTAATGAGCGCTATGAACAGATTATTAT
CATGGTTATGATTGTCTTTTGGTTAATTTCGATTTTAGCCAGTATTTATTTGGCTAAGTGGAGCAGAAAGCCAATTATGG
AGAGCTATGCTAAGCAAAAAATGTTTGTAGAAAATGCCAGTCATGAGCTTAGGACTCCTTTAGCGGTGCTGCAAAATCGT
TTGGAATCGCTGTTTAGAAAGCCTAACGAAACCATTTTAGACAATAGCGAGCATATTGCGTCAAGCCTAGATGAGGTTCG
TAATATGAGAATATTAACAACTAATCTGTTAAATTTAGCCAGACGTGATGATGGGATCAAGCCGCAGCTAGTTGATGTTG
ATGCAGCATTTTTTGACACTGTTTTTGAAAATTATCAATTAGTTGCAGAAGAATCAGGCAAGCAGTTTATCTCAGCTAAT
CAGATCAATAGGCCCTTAAAGACGGATAAGGCTTTGCTCAAGCAGCTGATGACCATTTTGTTTGATAATGCGATCAAATA
CACTGATCATAACGGTGTGGTTGAGGTCAAGGTTAGAACGACCGATAAGCATTTATTGATTTCTGTTATTGATAATGGCC
CAGGGATCAAGGATGATGATAAGAAAAAGATTTTTGATCGCTTTTACCGAGTGGATAAGGCAAGGACACGCCAAAAAGGA
GGCTTTGGACTCGGATTGGCCTTAGCGCAGCAGATCGTTACCTCATTAAAAGGAACGATTACCGTCAGTGATAATAAGCC
TACCGGCGCCATCTTTGAAGTAAAATTATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.895

100

0.58
  ciaH Streptococcus pneumoniae Rx1

51.376

100

0.514
  ciaH Streptococcus pneumoniae D39

51.376

100

0.514
  ciaH Streptococcus pneumoniae R6

51.376

100

0.514
  ciaH Streptococcus pneumoniae TIGR4

51.376

100

0.514

Multiple sequence alignment