Detailed information NTG1138967

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQM57_RS08600
• Genome accession: NZ_LS483369
• Coordinates: 1666610..1667803 (+)
• Length: 397 a.a.
• NCBI ID: WP_111727533.1
• Uniprot ID: A0A7T3EUI8
• Organism: Neisseria cinerea strain NCTC10294
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1661610..1672803

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM57_RS08585 (NCTC10294_01634)	-	1662535..1663131 (+)	597	WP_003677947.1	DUF4390 domain-containing protein	-
DQM57_RS08590 (NCTC10294_01635)	-	1663131..1665236 (+)	2106	WP_111727531.1	PAS domain-containing sensor histidine kinase	-
DQM57_RS08595 (NCTC10294_01636)	-	1665241..1666518 (+)	1278	WP_111727532.1	sigma-54 dependent transcriptional regulator	-
DQM57_RS08600 (NCTC10294_01637)	dprA	1666610..1667803 (+)	1194	WP_111727533.1	DNA-processing protein DprA	Machinery gene
DQM57_RS08605 (NCTC10294_01638)	-	1667826..1668287 (+)	462	WP_108044376.1	DUF494 domain-containing protein	-
DQM57_RS08610 (NCTC10294_01639)	topA	1668367..1670673 (+)	2307	WP_111727534.1	type I DNA topoisomerase	-
DQM57_RS08615 (NCTC10294_01640)	rsmD	1670782..1671351 (+)	570	WP_107996484.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQM57_RS08620 (NCTC10294_01641)	-	1671473..1671724 (+)	252	WP_003677924.1	YfhL family 4Fe-4S dicluster ferredoxin	-

Sequence

Protein

• Length: 397 a.a.
• Molecular weight: 42815.98 Da
• Isoelectric Point: 5.8227

>NTDB_id=1138967 DQM57_RS08600 WP_111727533.1 1666610..1667803(+) (dprA) [Neisseria cinerea strain NCTC10294]
MTENERFAWLQLAFTPYIGAESFLLLLHHFDSAQNALSAPAEQVAALIRHKQALEAWRGGDKRTVARQAAEAALEWEMRD
GCRLMLLRDDDFPEMLTQGITAPPVLFLRGNVQLLHKPSAAIVGSRHATPQAMRIAKDFGKSLGGQNIPVVSGMASGIDT
AAHQGALEAEGGTIAVWGTGIDRIYPPSNKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITARLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLVECLDDILHECPRLLQNEGASSYSINKGIPEKCITAVQT
ASDPPFSSEGKMPSEKTENRPVGGGILDRMGFDPVHPDVLAEQLGMPAADLYAELLELELDGSIAAMPGGRYQRIRT

Nucleotide

• Length: 1194 bp

>NTDB_id=1138967 DQM57_RS08600 WP_111727533.1 1666610..1667803(+) (dprA) [Neisseria cinerea strain NCTC10294]
ATGACAGAGAACGAACGTTTCGCATGGTTGCAGCTGGCTTTTACGCCCTATATCGGTGCGGAAAGTTTCTTGCTGCTGCT
GCACCATTTCGACAGTGCGCAAAATGCCCTGTCCGCACCGGCGGAACAGGTGGCGGCACTGATACGGCACAAACAGGCGC
TTGAGGCTTGGCGCGGCGGCGACAAACGTACTGTGGCACGGCAGGCCGCCGAAGCGGCATTGGAATGGGAAATGAGGGAC
GGATGCCGTCTGATGCTTCTGCGGGATGATGACTTTCCTGAAATGCTGACTCAGGGTATAACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCAACTGCTGCACAAACCTTCCGCCGCTATCGTCGGCAGCCGTCATGCCACGCCGCAGGCAATGC
GAATTGCCAAAGATTTCGGCAAGTCGTTGGGCGGGCAAAATATCCCCGTTGTGTCAGGTATGGCTTCCGGTATCGATACT
GCCGCCCATCAGGGCGCACTGGAGGCAGAAGGCGGCACCATCGCCGTGTGGGGGACAGGTATAGACCGCATTTACCCGCC
GTCCAATAAAAACCTTGCCTATGAAATCGCCGAAAAAGGACTGATTGTCAGCGAGTTTCCCATCGGTACGCGGCCGTATG
CCGGCAATTTTCCGCGCCGCAACCGCCTGATTGCCGCACTGTCGCAAGTAACGCTGGTGGTTGAAGCCGCATTGGAATCC
GGTTCGCTGATTACTGCCAGATTGGCAGCGGAGATGGGGCGCGAAGTGATGGCGGTACCCGGCTCGATAGACAATCCACA
CAGTAAAGGCTGCCACAAACTGATTAAAGACGGCGCAAAATTGGTGGAATGCCTGGACGACATCCTTCACGAGTGTCCGC
GGCTCTTGCAAAATGAGGGTGCTTCATCATATTCTATAAATAAGGGAATACCTGAAAAGTGCATCACTGCCGTTCAGACG
GCATCTGACCCGCCGTTTTCGTCTGAAGGCAAAATGCCGTCTGAAAAGACGGAGAACCGACCCGTCGGCGGCGGTATCTT
GGACAGGATGGGTTTCGACCCGGTTCATCCCGATGTGCTTGCCGAGCAGTTGGGTATGCCTGCCGCAGACTTATACGCCG
AACTGTTGGAATTGGAACTGGACGGCAGCATTGCCGCCATGCCTGGCGGAAGATACCAGCGTATCCGAACCTGA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (345-390)

• DNA recombination-mediator protein A (DNA_processg_A) (79-283)

3D structure

• AlphaFold DB: A0A7T3EUI8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria meningitidis strain C311	92.191	100	0.922
dprA	Neisseria meningitidis MC58	92.191	100	0.922
dprA	Neisseria gonorrhoeae strain FA1090	85.642	100	0.856
dprA	Neisseria gonorrhoeae MS11	85.39	100	0.854
dprA	Vibrio cholerae strain A1552	37.594	100	0.378
dprA	Vibrio campbellii strain DS40M4	36.923	98.237	0.363