Detailed information NTG1138912

Bioinformatically predicted

Overview

• Name: pknB
• Type: Regulator
• Locus tag: DQM56_RS07875
• Genome accession: NZ_LS483368
• Coordinates: 1644540..1646435 (-)
• Length: 631 a.a.
• NCBI ID: WP_043030078.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC6176
• Function: modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1643543..1644403	1644540..1646435	flank	137

Gene organization within MGE regions

Location: 1643543..1646435

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM56_RS07875 (NCTC6176_01598)	pknB	1644540..1646435 (-)	1896	WP_043030078.1	Stk1 family PASTA domain-containing Ser/Thr kinase	Regulator

Sequence

Protein

• Length: 631 a.a.
• Molecular weight: 68554.71 Da
• Isoelectric Point: 6.6073

>NTDB_id=1138912 DQM56_RS07875 WP_043030078.1 1644540..1646435(-) (pknB) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENPNVP
QALENVVIRATAKKLSDRYRSTFEMSRDLMTALSYNRSRERKVVFDDVESTKPLPKVTPTPVTAPKVSNASQASAAADAR
LEQTSQMDTLQKPQKKKKNGRFLGTLLKILFSFFVVGVALFAYLVLTKPTTVKVPDVTGSSLNAAKQVLEEAGLKVGKVH
QIESDTVSEDQVVKTNPQAGSAKRKGSSVDLYLSIGNKGFEMENYKGQDYQDVMTSLTETYGVPKSKIKIERIVTNEYPE
NTVISQSPSAGEKFNPAGKSKITLSVAVGDTVIMPMVTEYSYADAVNTLTALGIDAARIKAYVPSSSSPTGFVQVSSPSS
KAVVSGQTPYYGTQISLSEKGDISLYLYPEETRASSSSSSSDTSAPNPSAGDTTDSSSHTELGQNDAVTTP

Nucleotide

• Length: 1896 bp

>NTDB_id=1138912 DQM56_RS07875 WP_043030078.1 1644540..1646435(-) (pknB) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
ATGATTCAGATTGGCAAGCTATTTGCTGGTCGTTATCGCATTCTAAAATCTATAGGCCGCGGTGGTATGGCGGATGTTTA
TTTAGCAAACGATTTGATTCTGGATAATGAGGACGTTGCCATTAAGGTCTTGCGGACCAATTATCAAACAGATCAGGTTG
CTGTTGCGCGTTTTCAAAGAGAAGCGCGAGCCATGGCTGAATTAAATCACCCCAATATTGTTGCCATTCGGGATATAGGC
GAGGAAGACGGACAGCAATTTTTAGTAATGGAATATGTTGATGGCTCTGATTTGAAAAAATACATTCAGGATCATGCGCC
ATTATCTAACAATGAGGTGGTGAGAATCATGGAAGAGGTTCTTTCTGCCATGACTCTGGCCCACCAAAAAGGAATTGTTC
ACAGGGATTTAAAGCCTCAAAACATTCTTTTGACCAAATCAGGTGTTGTTAAGGTTACAGATTTTGGGATTGCCGTTGCC
TTTGCAGAGACCAGTCTAACCCAGACAAATTCTATGCTAGGAAGTGTGCATTACCTCTCACCTGAGCAAGCGCGTGGTTC
TAAAGCGACGATTCAAAGTGATATTTACGCGATGGGAATTATGCTCTTTGAAATGCTAACAGGGCATATTCCTTATGATG
GCGATAGCGCTGTGACGATTGCTTTGCAGCATTTTCAAAAGCCGCTGCCCTCTATCATTGATGAAAATCCTAATGTGCCT
CAAGCCTTGGAGAACGTCGTTATTCGGGCTACTGCCAAAAAGCTAAGTGACCGTTATCGCTCGACCTTTGAGATGAGCAG
GGACTTGATGACAGCCCTTAGCTATAACCGCAGTCGTGAGCGTAAGGTTGTCTTTGATGATGTCGAAAGCACAAAGCCCT
TGCCAAAGGTAACACCGACTCCTGTAACAGCACCTAAGGTATCAAATGCTAGTCAGGCATCTGCGGCAGCTGATGCTAGA
CTTGAGCAGACTAGCCAGATGGATACTCTGCAAAAGCCTCAAAAAAAGAAAAAAAATGGGCGTTTTCTAGGAACACTCTT
AAAAATCTTGTTTTCCTTTTTTGTTGTTGGTGTGGCTCTTTTTGCTTATTTGGTCTTGACCAAGCCAACTACGGTTAAGG
TTCCTGATGTGACAGGCTCTAGTCTCAATGCTGCCAAGCAGGTCTTGGAGGAGGCGGGACTAAAGGTCGGTAAGGTCCAT
CAGATTGAAAGTGACACAGTTAGTGAGGATCAGGTGGTTAAGACAAATCCTCAAGCTGGCTCAGCTAAGCGAAAAGGCTC
CAGCGTTGACCTTTACCTTTCGATCGGAAATAAAGGCTTTGAGATGGAAAATTATAAGGGACAGGATTATCAAGATGTGA
TGACCAGTCTGACCGAGACCTATGGCGTACCAAAGTCAAAAATCAAGATTGAGCGTATCGTGACAAATGAATACCCTGAA
AACACCGTTATTAGCCAGTCTCCAAGCGCAGGAGAAAAATTTAACCCAGCTGGTAAATCTAAGATTACTCTCAGTGTAGC
AGTGGGTGATACGGTCATCATGCCAATGGTAACTGAGTACAGCTATGCAGATGCAGTCAATACACTAACAGCTTTAGGAA
TTGATGCTGCAAGAATCAAGGCCTATGTACCAAGCTCCAGCTCTCCGACAGGCTTTGTGCAGGTGAGCTCCCCAAGCTCA
AAGGCGGTTGTCAGTGGGCAAACACCGTATTATGGTACCCAGATTAGCCTTTCTGAAAAGGGTGATATTAGCCTCTACCT
CTACCCTGAGGAGACACGTGCATCAAGTAGCTCATCGAGCTCTGATACCTCGGCTCCTAATCCATCAGCTGGAGATACAA
CAGACTCAAGCAGTCATACCGAATTAGGTCAAAATGACGCTGTTACAACACCGTAA

Domains

Predicted by InterproScan.

• Protein kinase domain (Pkinase) (12-232)

• PASTA domain (PASTA) (372-434)

• PASTA domain (PASTA) (512-588)

• PASTA domain (PASTA) (441-506)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pknB	Streptococcus mutans UA159	65.714	94.295	0.62
stkP/pknB	Streptococcus salivarius strain HSISS4	62.245	93.185	0.58
stkP	Streptococcus pneumoniae TIGR4	57.558	81.775	0.471
stkP	Streptococcus pneumoniae D39	57.171	81.775	0.468
stkP	Streptococcus pneumoniae R6	57.171	81.775	0.468
stkP	Streptococcus pneumoniae Rx1	56.977	81.775	0.466