Detailed information NTG1138899

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQM56_RS05110
• Genome accession: NZ_LS483368
• Coordinates: 1065073..1065918 (+)
• Length: 281 a.a.
• NCBI ID: WP_043983543.1
• Uniprot ID: A0A380JPG7
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC6176
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1060073..1070918

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM56_RS05090 (NCTC6176_01031)	-	1061556..1062188 (+)	633	Protein_969	putative bacteriocin export ABC transporter	-
DQM56_RS10185	-	1062595..1062812 (+)	218	Protein_970	DNA-binding protein	-
DQM56_RS05100 (NCTC6176_01032)	ylqF	1063200..1064054 (+)	855	WP_012677976.1	ribosome biogenesis GTPase YlqF	-
DQM56_RS05105 (NCTC6176_01033)	-	1064044..1064817 (+)	774	WP_111710934.1	ribonuclease HII	-
DQM56_RS05110 (NCTC6176_01034)	dprA	1065073..1065918 (+)	846	WP_043983543.1	DNA-processing protein DprA	Machinery gene
DQM56_RS05115 (NCTC6176_01035)	topA	1066019..1068151 (+)	2133	WP_111710562.1	type I DNA topoisomerase	-
DQM56_RS05120 (NCTC6176_01036)	-	1068266..1068913 (+)	648	WP_111710563.1	SatD family protein	-
DQM56_RS05125 (NCTC6176_01037)	-	1068934..1069647 (+)	714	WP_111710564.1	DUF3307 domain-containing protein	-

Sequence

Protein

• Length: 281 a.a.
• Molecular weight: 31334.24 Da
• Isoelectric Point: 8.8540

>NTDB_id=1138899 DQM56_RS05110 WP_043983543.1 1065073..1065918(+) (dprA) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
MNNFELYKLKKAGLTNLNILNLIDYQQRNNKSLSLRDMAVVSCCKNPVLFIETYKQLNVALLKKEFNQFPSLSILDKQYP
LALREIYNPPVLLFYQGDLSLLEKPKLAVVGSRESSEIGTRSVYKIVKELKNHFVIVSGLARGIDTSAHLACLKAGGQTI
AVIGTGLDRYYPKENHQLQEFLSQRHLVLSEYGAGEAALSYHFPERNRIIAGLSRGVLVVEAKQRSGSLITCQLAMEEGR
DIFVVPDNILNGTSAGCLKLIKDGASCVTHGRDILSEYHYS

Nucleotide

• Length: 846 bp

>NTDB_id=1138899 DQM56_RS05110 WP_043983543.1 1065073..1065918(+) (dprA) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
ATGAACAATTTTGAACTTTATAAATTAAAAAAGGCTGGGCTGACTAATTTAAATATTCTTAACCTTATTGACTACCAGCA
GCGTAATAATAAGTCTCTATCCCTTAGAGATATGGCAGTGGTTTCTTGCTGCAAAAATCCAGTTTTATTTATTGAAACCT
ACAAGCAATTAAATGTCGCCTTGTTAAAAAAGGAATTCAATCAGTTTCCGAGCTTATCTATCCTAGATAAGCAATACCCA
TTGGCTCTGAGGGAAATCTACAATCCTCCTGTTTTACTCTTTTATCAAGGTGATTTAAGCCTGTTAGAAAAGCCTAAGCT
GGCAGTCGTTGGCTCTAGAGAATCCAGTGAAATTGGGACGCGGTCTGTTTACAAAATCGTCAAAGAGCTTAAGAATCACT
TTGTCATTGTAAGTGGACTTGCTAGAGGTATTGATACCAGTGCTCATCTCGCTTGCTTGAAAGCAGGTGGGCAAACTATA
GCTGTTATCGGGACTGGCCTAGATCGCTACTATCCAAAGGAAAATCACCAGCTACAGGAGTTTTTATCTCAGCGTCATCT
CGTGCTCAGTGAATATGGGGCTGGAGAGGCCGCCTTGTCTTATCATTTCCCTGAAAGAAACCGTATTATCGCAGGTCTTA
GTCGAGGTGTCCTTGTTGTTGAGGCTAAGCAGCGCTCTGGCTCTTTGATTACCTGTCAGCTAGCTATGGAAGAGGGACGT
GATATTTTTGTCGTACCTGACAATATTCTTAATGGGACATCAGCGGGCTGTTTGAAGCTGATCAAAGATGGTGCCAGCTG
TGTCACTCATGGCAGAGACATTCTTTCAGAATACCACTATTCTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-61)

• DNA recombination-mediator protein A (DNA_processg_A) (71-269)

3D structure

• AlphaFold DB: A0A380JPG7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	68.571	99.644	0.683
dprA/cilB/dalA	Streptococcus mitis SK321	58.929	99.644	0.587
dprA/cilB/dalA	Streptococcus pneumoniae D39	58.571	99.644	0.584
dprA/cilB/dalA	Streptococcus pneumoniae R6	58.571	99.644	0.584
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	58.571	99.644	0.584
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	58.571	99.644	0.584
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	58.214	99.644	0.58
dprA	Lactococcus lactis subsp. cremoris KW2	57.295	100	0.573
dprA	Bacillus subtilis subsp. subtilis str. 168	42.4	88.968	0.377