Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   DQM52_RS03215 Genome accession   NZ_LS483367
Coordinates   587675..588385 (+) Length   236 a.a.
NCBI ID   WP_012766682.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC5371     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 582675..593385
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM52_RS03190 (NCTC5371_00642) - 583348..584343 (+) 996 WP_003057220.1 DUF3114 domain-containing protein -
  DQM52_RS03195 (NCTC5371_00643) - 584439..585086 (-) 648 WP_111681599.1 amino acid ABC transporter permease -
  DQM52_RS03200 (NCTC5371_00644) - 585101..585802 (-) 702 WP_046159505.1 amino acid ABC transporter permease -
  DQM52_RS03205 (NCTC5371_00645) - 585816..586616 (-) 801 WP_003057243.1 transporter substrate-binding domain-containing protein -
  DQM52_RS03210 (NCTC5371_00646) - 586643..587410 (-) 768 WP_111681600.1 amino acid ABC transporter ATP-binding protein -
  DQM52_RS03215 (NCTC5371_00647) vicR 587675..588385 (+) 711 WP_012766682.1 response regulator YycF Regulator
  DQM52_RS03220 (NCTC5371_00648) vicK 588378..589730 (+) 1353 WP_022554366.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQM52_RS03225 (NCTC5371_00649) vicX 589734..590543 (+) 810 WP_003059746.1 MBL fold metallo-hydrolase Regulator
  DQM52_RS03230 (NCTC5371_00650) - 591131..591994 (-) 864 WP_003060834.1 IS982 family transposase -
  DQM52_RS03235 (NCTC5371_00651) rnc 592269..592961 (+) 693 WP_003057240.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27057.95 Da        Isoelectric Point: 5.0023

>NTDB_id=1138836 DQM52_RS03215 WP_012766682.1 587675..588385(+) (vicR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5371]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFVAKKHGKEVE
LTHREFELLHHLANHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1138836 DQM52_RS03215 WP_012766682.1 587675..588385(+) (vicR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5371]
ATGAAAAAAATACTGATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAATTTGACAAAAGAAGGTTATGA
CATTGTTACAGCTTTTGATGGACGCGAAGCGGTAACAATTTTTGAAGAAGAAAAGCCAGATTTAATTATTCTTGATTTGA
TGCTCCCTGAGTTGGACGGTCTTGAAGTAGCCAAGGAAATTCGTAAAACCAGTCATGTCCCGATTATTATGCTGTCGGCT
AAGGATAGTGAGTTTGACAAGGTCATTGGTCTTGAAATTGGGGCAGATGATTATGTTACCAAACCTTTTTCAAATCGTGA
ACTATTAGCTCGTGTCAAGGCTCATTTACGTCGAACAGAAACGATCGAAACAGCCGTAGCAGAGGAAAATGCTTCTTCAG
GTTCACAAGAGTTAACCATTGGTAATTTACAAATTTTACCAGATGCTTTTGTGGCTAAAAAACATGGCAAAGAAGTGGAA
TTAACCCATCGTGAATTTGAATTATTACACCACCTGGCCAATCATATGGGTCAAGTGATGACACGAGAGCACTTGCTTGA
GACGGTTTGGGGCTATGATTACTTTGGCGATGTCCGTACTGTTGACGTGACGGTTCGTCGTCTGCGTGAAAAAATTGAAG
ACACACCAAGCCGTCCCGAATATATTTTAACGAGACGCGGTGTTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.678

100

0.907
  micA Streptococcus pneumoniae Cp1015

79.487

99.153

0.788
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.828

98.305

0.441
  scnR Streptococcus mutans UA159

37.712

100

0.377

Multiple sequence alignment