Detailed information NTG1138810

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: DQM60_RS10375
• Genome accession: NZ_LS483366
• Coordinates: 2182474..2183709 (+)
• Length: 411 a.a.
• NCBI ID: WP_013991347.1
• Uniprot ID: A0AB37CMH1
• Organism: Streptococcus salivarius strain NCTC7366
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2177474..2188709

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM60_RS10345 (NCTC7366_02092)	-	2177941..2180535 (+)	2595	WP_049528176.1	YfhO family protein	-
DQM60_RS10365 (NCTC7366_02096)	-	2181090..2181773 (-)	684	WP_013991345.1	YoaK family protein	-
DQM60_RS10370 (NCTC7366_02097)	rlmH	2181789..2182268 (-)	480	WP_014632473.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
DQM60_RS10375 (NCTC7366_02098)	htrA	2182474..2183709 (+)	1236	WP_013991347.1	S1C family serine protease	Regulator
DQM60_RS10380 (NCTC7366_02099)	spo0J	2183776..2184543 (+)	768	WP_014635206.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42915.09 Da
• Isoelectric Point: 4.6266

>NTDB_id=1138810 DQM60_RS10375 WP_013991347.1 2182474..2183709(+) (htrA) [Streptococcus salivarius strain NCTC7366]
MKKFNWKKIVAPIAMLVIGLLGGLLGAFILLTAAGVSFTNSTDTGVKTAKTVYNNTTDTTKAVKKVQNAVVSVINYQEGS
SSDSLNELYGRIFGGDDSSDSSQDKSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKIKTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTVTMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISMADLNSLS
SSATSKLDLPDDVKAGVVVGSVQKGMPADGKLQENDVITEIDGKEISSKTDIQTNLYSHSIGDTIKVTFYRGKEKKTEEL
KLTKSTEDLSD

Nucleotide

• Length: 1236 bp

>NTDB_id=1138810 DQM60_RS10375 WP_013991347.1 2182474..2183709(+) (htrA) [Streptococcus salivarius strain NCTC7366]
GTGAAAAAATTTAACTGGAAAAAAATAGTAGCGCCAATTGCAATGCTTGTTATTGGCTTGCTCGGTGGTTTGCTAGGTGC
CTTTATCCTACTAACAGCAGCAGGGGTATCTTTTACCAATTCAACAGATACAGGTGTTAAAACAGCTAAGACCGTATACA
ATAATACAACAGATACAACTAAAGCTGTTAAGAAAGTACAAAATGCTGTTGTTTCTGTCATCAATTACCAAGAAGGGTCA
TCTTCAGATTCTCTAAATGAACTTTATGGCCGTATCTTTGGTGGAGATGATAGTTCTGACTCTAGCCAAGACAAATCAAA
AGATTCTGATGGGTTACAAGTCGCTGGTGAAGGTTCCGGTGTTATCTATAAAAAGGATGGTAAAGAGGCTTATATCGTAA
CCAACAACCACGTTGTCGATGGCGCTAAAAAACTTGAAATCATGCTTTCAGATGGATCAAAAATTACTGGTGAACTCGTT
GGTAAAGATACTTACTCTGACCTAGCAGTTGTCAAAGTTTCTTCAGATAAAATTAAAACCGTAGCGGAATTTGCAGACTC
AAACTCTCTCACAGTCGGTGAGAAGGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAGG
GAATCGTTTCTAGCCTTAGCCGTACCGTAACTATGCAAAACGACAATGGTGAAACTGTTTCAACAAATGCTATTCAAACA
GATGCTGCCATTAACCCTGGTAACTCAGGTGGTGCCTTAGTCAATATCGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCAGCAGTCGCTGGTAGCGCCGTTGAAGGTATGGGATTTGCCATTCCATCAAACGATGTTGTCGAAA
TCATCAATCAATTGGAAAAAGACGGTAAAGTTACACGACCAGCCCTAGGAATCTCAATGGCCGATCTTAATAGCCTTTCT
AGCAGTGCAACTTCTAAATTAGATTTACCAGATGATGTGAAAGCTGGAGTTGTAGTCGGCAGCGTTCAAAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAAAATGATGTTATCACTGAAATTGACGGTAAGGAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATTGGAGATACAATCAAGGTAACCTTCTATCGTGGTAAAGAGAAGAAAACTGAAGAACTT
AAATTAACAAAATCTACAGAAGACTTGTCTGACTAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (7-406)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• PDZ domain (PDZ_2) (307-402)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.787	98.054	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.389	98.783	0.567
htrA	Streptococcus pneumoniae Rx1	54.279	99.513	0.54
htrA	Streptococcus pneumoniae R6	54.279	99.513	0.54
htrA	Streptococcus pneumoniae TIGR4	54.279	99.513	0.54
htrA	Streptococcus pneumoniae D39	54.279	99.513	0.54
htrA	Streptococcus mitis NCTC 12261	54.279	99.513	0.54