Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DQM60_RS01615 Genome accession   NZ_LS483366
Coordinates   296611..297300 (+) Length   229 a.a.
NCBI ID   WP_002886589.1    Uniprot ID   -
Organism   Streptococcus salivarius strain NCTC7366     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 291611..302300
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM60_RS01590 (NCTC7366_00319) - 291843..292673 (+) 831 WP_073686621.1 energy-coupling factor transporter transmembrane component T family protein -
  DQM60_RS01595 (NCTC7366_00320) - 292763..293434 (-) 672 WP_073686620.1 potassium channel family protein -
  DQM60_RS01600 (NCTC7366_00321) - 293474..294838 (-) 1365 WP_111686475.1 TrkH family potassium uptake protein -
  DQM60_RS01605 (NCTC7366_00322) rsmG 294907..295620 (-) 714 WP_013990060.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  DQM60_RS01610 (NCTC7366_00323) - 295919..296455 (+) 537 WP_070579518.1 DUF177 domain-containing protein -
  DQM60_RS01615 (NCTC7366_00324) covR 296611..297300 (+) 690 WP_002886589.1 response regulator transcription factor Regulator
  DQM60_RS01620 (NCTC7366_00325) covS 297297..298826 (+) 1530 WP_002886591.1 HAMP domain-containing histidine kinase Regulator
  DQM60_RS01625 (NCTC7366_00326) nrdR 298948..299427 (+) 480 WP_002886592.1 transcriptional regulator NrdR -
  DQM60_RS01630 (NCTC7366_00327) - 299424..300599 (+) 1176 WP_013990063.1 DnaD domain protein -
  DQM60_RS01635 (NCTC7366_00328) dnaI 300603..301505 (+) 903 WP_013990064.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26517.51 Da        Isoelectric Point: 4.6354

>NTDB_id=1138759 DQM60_RS01615 WP_002886589.1 296611..297300(+) (covR) [Streptococcus salivarius strain NCTC7366]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIESAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1138759 DQM60_RS01615 WP_002886589.1 296611..297300(+) (covR) [Streptococcus salivarius strain NCTC7366]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTCGAGAAAGATTTTGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGATTCAATCATGGACATTGTTGCTGGTTTGGACCGCGGTGCTGATGACTATATTGTAAAACCATTTGCGATTGA
AGAATTGTTGGCACGTATCCGTGCAACCTTCCGTCGCCAAGATATCGAATCTGCTAAGAATGCACCAGCAAAAGCATCAA
CTTATCGTGATTTGAAATTGGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGACGCCATCGAAACAAACGTGGTAGATGTTTATATTCGTTATTTGCGTGGAAAAATCGACGTTCCAGGTAAGGAAT
CATATATTCAAACAGTACGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

99.563

100

0.996
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

46.352

100

0.472
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445

Multiple sequence alignment