Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   DQM60_RS01620 Genome accession   NZ_LS483366
Coordinates   297297..298826 (+) Length   509 a.a.
NCBI ID   WP_002886591.1    Uniprot ID   -
Organism   Streptococcus salivarius strain NCTC7366     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 292297..303826
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM60_RS01595 (NCTC7366_00320) - 292763..293434 (-) 672 WP_073686620.1 potassium channel family protein -
  DQM60_RS01600 (NCTC7366_00321) - 293474..294838 (-) 1365 WP_111686475.1 TrkH family potassium uptake protein -
  DQM60_RS01605 (NCTC7366_00322) rsmG 294907..295620 (-) 714 WP_013990060.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  DQM60_RS01610 (NCTC7366_00323) - 295919..296455 (+) 537 WP_070579518.1 DUF177 domain-containing protein -
  DQM60_RS01615 (NCTC7366_00324) covR 296611..297300 (+) 690 WP_002886589.1 response regulator transcription factor Regulator
  DQM60_RS01620 (NCTC7366_00325) covS 297297..298826 (+) 1530 WP_002886591.1 HAMP domain-containing histidine kinase Regulator
  DQM60_RS01625 (NCTC7366_00326) nrdR 298948..299427 (+) 480 WP_002886592.1 transcriptional regulator NrdR -
  DQM60_RS01630 (NCTC7366_00327) - 299424..300599 (+) 1176 WP_013990063.1 DnaD domain protein -
  DQM60_RS01635 (NCTC7366_00328) dnaI 300603..301505 (+) 903 WP_013990064.1 primosomal protein DnaI -
  DQM60_RS01640 (NCTC7366_00329) der 301610..302920 (+) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  DQM60_RS01645 (NCTC7366_00330) - 302984..303613 (+) 630 WP_073686617.1 ribonuclease P -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58137.57 Da        Isoelectric Point: 5.3949

>NTDB_id=1138760 DQM60_RS01620 WP_002886591.1 297297..298826(+) (covS) [Streptococcus salivarius strain NCTC7366]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSLFTLVVIFSANTLLLQRERQNVNTTIAKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLVFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERLAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDINHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADRETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=1138760 DQM60_RS01620 WP_002886591.1 297297..298826(+) (covS) [Streptococcus salivarius strain NCTC7366]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGTTGTTCACTCTGGTTGTTATTTTTTCAGCTAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAA
ACACTACAATCGCAAAAGTTGTTACTTACATCGAAAAGGATTGGGATTCGGATGAAGAATTAAGTCCAGAACCGCTCTTA
GCGGCTCTTTATTCGCCTAAAAATATCTATGCATCAATTATTAATGGCGTACTTTCTGAAAAGCACTCTTTGGATGGTCA
AGTTGCAATTTCTAATAAATTATATTCAAATCAGTCAGTTTTTGTGTATGACAAAAAAGGAACCTTTATCTTTACTTCTG
AGGAGAATACAGATTCGCCTCCCGGTATGTCCGAGGTAAACAAACTGAAGTCAGTATCCTATAAAGGAAAGCGTGGTTTC
TTACTACAAGTTCCAATTTACGGTAAGGATAAAAAGACCATCGTTGGCTATGCCCAGATTTTCCATGATTTGGAATTCTA
CTATGCTCTTAAAGAGCGTTTGGTTTTCTTGTTGATTTTCCTAGAAGTGGGGATGACTGTCCTAGTTATCGCAGCAACTG
TAGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATTACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGCATGATGGATAAAAT
TCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTGCGTACGCCGATTGCGGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAAGAAAGTCTTGAGGCTGCAAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCATAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGGAACTTCCGTGTCTTGCATGAAGATTATCAATTTTATCTCA
ATGATTTCGAAAGTTCAGAGCGTCTAGCACAGATTTATAGTCAGCACTTTGAACAGGCGATCACCATTTTGATTGATAAT
GCGGTCAAGTATTCGCCTGTCAATAAGGAAATACAGGTTACTATTAAAGCATTGGAAGATGAAATGTTGGTACAAGTGCA
AGATAACGGTGAGGGAATTTCAAAAGAAGATATCAATCATATTTTTGAACGTTTCTATCGTTCAGATAAGGCACGTAACC
GTACAACAACTCAATCTGGTGTTGGTATTGGTTTGTCAATCCTTTATCAAATTGTGGAAGCTTATCGCTGCCGAATTGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCAGATCGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)

HAMP domain (HAMP)

(217-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

98.625

100

0.986

Multiple sequence alignment