Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DQM60_RS00970 Genome accession   NZ_LS483366
Coordinates   168915..169664 (+) Length   249 a.a.
NCBI ID   WP_014633671.1    Uniprot ID   A0AAX1YC61
Organism   Streptococcus salivarius strain NCTC7366     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 163915..174664
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM60_RS00950 (NCTC7366_00189) - 164930..165670 (-) 741 WP_013989971.1 amino acid ABC transporter ATP-binding protein -
  DQM60_RS00955 (NCTC7366_00190) - 165670..167217 (-) 1548 WP_002886433.1 ABC transporter substrate-binding protein/permease -
  DQM60_RS00960 (NCTC7366_00191) - 167423..168277 (+) 855 WP_002883622.1 undecaprenyl-diphosphate phosphatase -
  DQM60_RS00965 (NCTC7366_00192) - 168337..168708 (-) 372 WP_045001980.1 DUF3021 family protein -
  DQM60_RS00970 (NCTC7366_00193) mecA 168915..169664 (+) 750 WP_014633671.1 adaptor protein MecA Regulator
  DQM60_RS00975 (NCTC7366_00194) - 169668..170825 (+) 1158 WP_014633670.1 glycosyltransferase family 4 protein -
  DQM60_RS00980 (NCTC7366_00195) sufC 170987..171757 (+) 771 WP_002883600.1 Fe-S cluster assembly ATPase SufC -
  DQM60_RS00985 (NCTC7366_00196) sufD 171794..173056 (+) 1263 WP_002886437.1 Fe-S cluster assembly protein SufD -
  DQM60_RS00990 (NCTC7366_00197) - 173110..174342 (+) 1233 WP_084871118.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29146.75 Da        Isoelectric Point: 4.0356

>NTDB_id=1138750 DQM60_RS00970 WP_014633671.1 168915..169664(+) (mecA) [Streptococcus salivarius strain NCTC7366]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSYMDDYSGLSPEEFLKALEGNFMDKGDIEAHHKLEELEKTLEEVDKAMTEPTKEVPEENIREDYTHYVLAF
SDFDQVVTFTQGLKDVPVEGSELYKLGDVYYMTVLLYLADEPDYYANNMYARFLEYANVADRTRAYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=1138750 DQM60_RS00970 WP_014633671.1 168915..169664(+) (mecA) [Streptococcus salivarius strain NCTC7366]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAATT
GAAGGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGCTGAGCTTCCGTGTCACGCCACGCAAGGATCGTGTGGATGTCTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAACGATTTGTCATATATGGATGACTACTCAGGGCTTTCTCCAGAAGAGTTCCTCAAGGCTCT
TGAGGGTAACTTTATGGACAAGGGTGACATCGAAGCACACCATAAGCTCGAAGAGCTTGAAAAGACCTTGGAAGAGGTTG
ATAAGGCTATGACAGAGCCTACCAAGGAAGTGCCCGAAGAAAATATTCGTGAAGACTATACCCACTATGTCTTGGCCTTC
TCTGACTTTGATCAAGTGGTGACCTTTACACAAGGCTTGAAGGATGTGCCTGTTGAAGGTTCTGAGCTTTATAAACTTGG
GGATGTCTACTATATGACAGTCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTAGCAGACCGAACACGTGCCTACCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTACTACAAGCAACGAAATGGAGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

93.173

100

0.932
  mecA Streptococcus thermophilus LMG 18311

92.369

100

0.924
  mecA Streptococcus mutans UA159

60.246

97.992

0.59
  mecA Streptococcus pneumoniae Rx1

46.586

100

0.466
  mecA Streptococcus pneumoniae D39

46.586

100

0.466
  mecA Streptococcus pneumoniae R6

46.586

100

0.466
  mecA Streptococcus pneumoniae TIGR4

46.586

100

0.466

Multiple sequence alignment