Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   Q426_RS00255 Genome accession   NZ_CP006770
Coordinates   55471..56235 (+) Length   254 a.a.
NCBI ID   WP_014623472.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus CY     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 50471..61235
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q426_RS10175 (Q426_00260) - 51452..51568 (-) 117 WP_012677375.1 putative metal homeostasis protein -
  Q426_RS00240 (Q426_00265) - 51895..52635 (-) 741 WP_014623475.1 amino acid ABC transporter ATP-binding protein -
  Q426_RS00245 (Q426_00270) - 52628..54196 (-) 1569 WP_014623474.1 ABC transporter substrate-binding protein/permease -
  Q426_RS00250 (Q426_00275) - 54512..55351 (+) 840 WP_014623473.1 undecaprenyl-diphosphate phosphatase -
  Q426_RS00255 (Q426_00280) mecA 55471..56235 (+) 765 WP_014623472.1 adaptor protein MecA Regulator
  Q426_RS00260 (Q426_00285) - 56242..57399 (+) 1158 WP_038674746.1 glycosyltransferase family 4 protein -
  Q426_RS00265 (Q426_00290) sufC 57520..58290 (+) 771 WP_014623470.1 Fe-S cluster assembly ATPase SufC -
  Q426_RS00270 (Q426_00295) sufD 58382..59644 (+) 1263 WP_014623469.1 Fe-S cluster assembly protein SufD -
  Q426_RS00275 (Q426_00300) - 59671..60897 (+) 1227 WP_014623468.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 254 a.a.        Molecular weight: 29332.18 Da        Isoelectric Point: 4.2602

>NTDB_id=113875 Q426_RS00255 WP_014623472.1 55471..56235(+) (mecA) [Streptococcus equi subsp. zooepidemicus CY]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDL
NKDLNFEDLADLGDISQMTPEDFFRSLEQSMREKGDVNAHEKLEKIEEIMEDVVDATLAEQADNKEAAELEEPTEPLDYV
HYVLDFASVRDAVCFAKAIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARLIEHARPGTKTRAYLQEHGCQLI
FDGAVEELQKIRLG

Nucleotide


Download         Length: 765 bp        

>NTDB_id=113875 Q426_RS00255 WP_014623472.1 55471..56235(+) (mecA) [Streptococcus equi subsp. zooepidemicus CY]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGGGGTATGGAACT
CAAGGACTTCTTGATCCCTCAAGAAAAGACAGAGGAGTTCTTTTATGCTGTTATGGACGAGTTGGACCTTCCGGACAATT
TTAAGGACAGTGGTATGCTTAGCTTTCGAGTGACCCCAAGAAAGGATCGCTTAGATGTTTTTGTGACCAAGTCAGACCTC
AATAAGGACCTTAATTTTGAGGATTTGGCAGACCTAGGTGATATTTCTCAAATGACTCCAGAGGATTTTTTCAGGAGCTT
GGAGCAGTCTATGCGTGAAAAGGGTGATGTTAATGCCCATGAAAAGCTCGAAAAAATTGAGGAGATCATGGAGGACGTGG
TTGATGCTACCTTGGCTGAGCAAGCAGATAATAAGGAAGCTGCTGAGCTTGAAGAGCCGACAGAGCCACTTGATTACGTT
CACTATGTTCTTGATTTTGCTTCTGTGCGAGACGCTGTTTGCTTTGCTAAGGCGATTGATTTTCCGATCGAGGCTTCTGA
ATTGTATAAGGGTCCTCGTCATTATCACATGACGATTTTACTTGATGTGCAAAACAAGCCTGCCTACTTTGCCAATGTGA
TGTATGCCAGATTGATTGAGCATGCTAGACCTGGTACAAAAACAAGAGCTTATTTGCAGGAGCATGGTTGTCAGCTCATT
TTTGATGGTGCTGTTGAGGAGCTGCAAAAAATCAGGTTGGGGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.745

98.819

0.63
  mecA Streptococcus thermophilus LMD-9

56.471

100

0.567
  mecA Streptococcus thermophilus LMG 18311

55.686

100

0.559
  mecA Streptococcus pneumoniae TIGR4

48.031

100

0.48
  mecA Streptococcus pneumoniae Rx1

47.638

100

0.476
  mecA Streptococcus pneumoniae D39

47.638

100

0.476
  mecA Streptococcus pneumoniae R6

47.638

100

0.476

Multiple sequence alignment