Detailed information NTG1138703

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: DQM55_RS11685
• Genome accession: NZ_LS483364
• Coordinates: 2329177..2330349 (+)
• Length: 390 a.a.
• NCBI ID: WP_111676898.1
• Uniprot ID: -
• Organism: Streptococcus sanguinis strain NCTC11086
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2324177..2335349

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM55_RS11660 (NCTC11086_02357)	comE	2325957..2326721 (-)	765	WP_002899424.1	competence system response regulator transcription factor ComE	Regulator
DQM55_RS11665 (NCTC11086_02358)	comD	2326727..2328061 (-)	1335	WP_111676894.1	competence system sensor histidine kinase ComD	-
DQM55_RS11670 (NCTC11086_02359)	-	2328089..2328196 (-)	108	WP_032909851.1	hypothetical protein	-
DQM55_RS11680 (NCTC11086_02361)	rlmH	2328494..2328973 (-)	480	WP_111676896.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
DQM55_RS11685 (NCTC11086_02362)	htrA	2329177..2330349 (+)	1173	WP_111676898.1	S1C family serine protease	Regulator
DQM55_RS11690 (NCTC11086_02363)	spo0J	2330413..2331174 (+)	762	WP_172454777.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 390 a.a.
• Molecular weight: 40898.71 Da
• Isoelectric Point: 4.8344

>NTDB_id=1138703 DQM55_RS11685 WP_111676898.1 2329177..2330349(+) (htrA) [Streptococcus sanguinis strain NCTC11086]
MKNSSNAIKKALLLFAVLIVGFIGGSLGNYVTTLVTSRVKMNGNSTTSVTTSYKNSTDISEAVKKVQNAVVSVITYAESS
SSVINDESSNDESQISSEGSGVIYKKDGKSAYLVTNTHVLNGSTNVDILLADGNKVPGEVVGSDVYSDISVVKISSEKVT
DVAEFGDSKSLTVGETAIAIGSPLGTEYANSVTQGIISSLGRNVTLQSENGENISTTALQTDAAINPGNSGGPLINIQGQ
VIGITSSKISTNGQTSVEGMGFAIPSNDVVNIINQLEKNGTVTRPALGIQMMDLSNLTTSDFSKLNLPSSVKSGILVRSV
QQGMPADGKLQKNDVITKVDNTDVESTSDLQSALYKHSIGDEVEITYYRDGKSQTVKIKLTKSTKELSSN

Nucleotide

• Length: 1173 bp

>NTDB_id=1138703 DQM55_RS11685 WP_111676898.1 2329177..2330349(+) (htrA) [Streptococcus sanguinis strain NCTC11086]
ATGAAAAACTCTTCAAATGCCATCAAAAAGGCTTTATTGCTTTTTGCAGTGTTAATTGTAGGTTTTATCGGCGGAAGTTT
AGGGAATTATGTTACTACATTAGTAACTTCACGTGTAAAAATGAATGGAAATTCAACAACCAGTGTAACTACTTCATATA
AAAACTCTACAGACATTTCAGAAGCTGTGAAAAAGGTTCAAAATGCGGTTGTTTCAGTAATTACTTATGCTGAATCTTCT
AGCAGCGTTATCAATGATGAATCTTCCAACGATGAATCACAAATCTCCAGTGAAGGTTCTGGCGTAATTTATAAAAAAGA
CGGAAAATCAGCCTATCTGGTAACCAACACCCACGTTCTTAACGGATCAACCAATGTAGATATCTTGCTAGCTGATGGAA
ACAAGGTTCCAGGAGAAGTAGTTGGATCAGATGTTTATTCAGATATTTCTGTCGTTAAAATTAGCTCTGAAAAAGTAACT
GATGTTGCTGAATTTGGAGATTCTAAATCTCTGACAGTTGGTGAGACAGCTATTGCTATCGGAAGTCCTCTTGGAACAGA
ATACGCTAACTCTGTCACACAAGGAATTATTTCTAGTTTAGGCAGAAACGTTACATTACAATCTGAAAATGGTGAAAATA
TTTCAACAACTGCACTGCAAACAGATGCTGCAATCAATCCTGGTAACTCTGGCGGCCCATTGATTAACATCCAAGGACAA
GTTATTGGGATTACTTCAAGTAAAATTTCAACAAATGGCCAAACCTCTGTTGAAGGGATGGGATTTGCCATTCCATCTAA
TGATGTCGTAAATATTATCAATCAACTTGAGAAAAATGGAACAGTCACACGTCCTGCTTTAGGGATTCAAATGATGGATT
TATCTAATCTGACAACTTCTGATTTTTCTAAATTAAATCTTCCTTCTTCAGTGAAATCAGGTATTCTTGTTCGCTCTGTT
CAGCAAGGGATGCCTGCTGATGGCAAGCTTCAAAAAAATGACGTCATTACAAAAGTAGATAATACAGATGTGGAATCCAC
TAGTGATTTACAATCTGCTCTCTACAAGCATAGTATTGGAGATGAAGTAGAAATTACTTATTATCGAGATGGTAAATCTC
AAACAGTCAAAATCAAACTCACTAAATCAACAAAAGAGTTAAGCTCAAATTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (285-380)

• Peptidase family M50 (Peptidase_M50) (231-385)

• Trypsin-like peptidase domain (Trypsin_2) (99-244)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	67.677	100	0.687
htrA	Streptococcus mitis NCTC 12261	64.122	100	0.646
htrA	Streptococcus pneumoniae Rx1	64.122	100	0.646
htrA	Streptococcus pneumoniae D39	64.122	100	0.646
htrA	Streptococcus pneumoniae R6	64.122	100	0.646
htrA	Streptococcus pneumoniae TIGR4	64.122	100	0.646
htrA	Streptococcus mutans UA159	54.937	100	0.556