Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   DQM55_RS05975 Genome accession   NZ_LS483364
Coordinates   1150258..1151100 (+) Length   280 a.a.
NCBI ID   WP_111675807.1    Uniprot ID   A0A2X4ALU6
Organism   Streptococcus sanguinis strain NCTC11086     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1145258..1156100
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM55_RS05940 (NCTC11086_01237) dapA 1145466..1146401 (+) 936 WP_111675801.1 4-hydroxy-tetrahydrodipicolinate synthase -
  DQM55_RS05950 (NCTC11086_01238) - 1146645..1146983 (+) 339 WP_111675802.1 ATP cone domain-containing protein -
  DQM55_RS05955 (NCTC11086_01239) ylqF 1147125..1147976 (+) 852 WP_111675803.1 ribosome biogenesis GTPase YlqF -
  DQM55_RS05960 (NCTC11086_01240) - 1147963..1148727 (+) 765 WP_111675804.1 ribonuclease HII -
  DQM55_RS05965 (NCTC11086_01241) - 1148745..1149587 (+) 843 WP_111675805.1 PRD domain-containing protein -
  DQM55_RS05970 (NCTC11086_01242) - 1149563..1150126 (+) 564 WP_111675806.1 sugar O-acetyltransferase -
  DQM55_RS05975 (NCTC11086_01243) dprA/cilB/dalA 1150258..1151100 (+) 843 WP_111675807.1 DNA-processing protein DprA Machinery gene
  DQM55_RS05980 (NCTC11086_01244) topA 1151185..1153278 (+) 2094 WP_111675808.1 type I DNA topoisomerase -
  DQM55_RS05985 (NCTC11086_01245) - 1153336..1153836 (+) 501 WP_111675809.1 phosphoribosylanthranilate isomerase -
  DQM55_RS05990 (NCTC11086_01246) - 1153833..1154777 (+) 945 WP_111675810.1 hypothetical protein -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31040.68 Da        Isoelectric Point: 6.7409

>NTDB_id=1138669 DQM55_RS05975 WP_111675807.1 1150258..1151100(+) (dprA/cilB/dalA) [Streptococcus sanguinis strain NCTC11086]
MNNFEIYKMKKAGLTNHQVLNVLRYAESRDSKLSLRDKAVVSECRNPALFIEKYKRLDLPALKEEFELFPSFSILDDIYP
WDLCEIYDAPTLLFYQGNLNLLELPKAAVVGSRDSSKQGNASVQKIVKELNNELVIVSGLARGIDTAAHMAALQNGGQTI
AVIGTGLDVFYPKANKKLQSYIGKNHLLLTEYGPSEQPLKFHFPERNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGR
DVFAIPGSILDGKSDGCHHLIQEGAKCITSGSDVLSEFDF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=1138669 DQM55_RS05975 WP_111675807.1 1150258..1151100(+) (dprA/cilB/dalA) [Streptococcus sanguinis strain NCTC11086]
ATGAATAATTTTGAGATTTATAAAATGAAAAAAGCTGGTTTGACTAATCATCAGGTTTTAAATGTTTTGAGATACGCCGA
GAGTAGAGATAGCAAGCTTTCTCTCCGAGATAAGGCTGTCGTATCTGAGTGCCGTAATCCCGCTCTCTTTATAGAGAAGT
ATAAACGTCTTGATCTACCAGCTTTGAAGGAAGAATTCGAACTTTTTCCGTCCTTTTCTATCTTGGATGATATTTACCCT
TGGGATTTATGTGAGATTTATGATGCCCCGACTTTGTTATTTTATCAGGGAAATCTAAATCTACTAGAATTGCCCAAGGC
TGCAGTCGTTGGCAGTCGAGACAGCAGCAAGCAAGGAAATGCCTCCGTACAAAAGATTGTCAAGGAGCTAAATAATGAAT
TGGTTATCGTTAGTGGCCTAGCTCGTGGAATAGATACAGCGGCTCATATGGCTGCCCTGCAAAACGGGGGGCAGACGATT
GCTGTCATCGGAACAGGATTAGATGTCTTTTATCCCAAAGCAAACAAAAAATTACAATCTTACATTGGCAAAAATCATTT
ATTGCTGACAGAGTATGGTCCAAGTGAACAGCCTTTGAAGTTTCATTTTCCAGAGCGGAATCGGATCATCGCTGGTCTCT
GTCGTGGCGTCATCGTGGCAGAAGCTAAGATGCGCTCAGGCAGCCTGATTACCTGTGAGCGAGCGATGGAAGAAGGGCGA
GATGTCTTTGCTATTCCGGGGTCAATTTTAGATGGGAAATCTGACGGTTGCCATCATTTGATTCAAGAGGGCGCAAAGTG
CATCACATCAGGCTCTGACGTTCTTTCTGAATTTGATTTTTAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-61)

DNA recombination-mediator protein A (DNA_processg_A)

(74-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X4ALU6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

76.429

100

0.764
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

76.071

100

0.761
  dprA/cilB/dalA Streptococcus pneumoniae D39

76.071

100

0.761
  dprA/cilB/dalA Streptococcus pneumoniae R6

76.071

100

0.761
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

76.071

100

0.761
  dprA/cilB/dalA Streptococcus mitis SK321

75.714

100

0.757
  dprA Streptococcus mutans UA159

66.786

100

0.668
  dprA Lactococcus lactis subsp. cremoris KW2

57.194

99.286

0.568

Multiple sequence alignment