Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   DQM55_RS02785 Genome accession   NZ_LS483364
Coordinates   541541..543394 (+) Length   617 a.a.
NCBI ID   WP_002926514.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC11086     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 536541..548394
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM55_RS02770 (NCTC11086_00550) fmt 538544..539479 (+) 936 WP_111675395.1 methionyl-tRNA formyltransferase -
  DQM55_RS02775 (NCTC11086_00551) rsmB 539469..540785 (+) 1317 WP_002926518.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  DQM55_RS02780 (NCTC11086_00552) - 540804..541544 (+) 741 WP_002926516.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DQM55_RS02785 (NCTC11086_00553) stkP 541541..543394 (+) 1854 WP_002926514.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DQM55_RS02790 (NCTC11086_00554) liaF 543540..544235 (+) 696 WP_002893496.1 cell wall-active antibiotics response protein LiaF -
  DQM55_RS02795 (NCTC11086_00555) - 544232..545251 (+) 1020 WP_061592661.1 sensor histidine kinase -
  DQM55_RS02800 (NCTC11086_00556) - 545229..545861 (+) 633 WP_111675396.1 response regulator transcription factor -
  DQM55_RS02805 (NCTC11086_00557) - 545901..547301 (+) 1401 WP_111675397.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQM55_RS02810 (NCTC11086_00558) - 547301..547663 (+) 363 WP_111675398.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 617 a.a.        Molecular weight: 67427.26 Da        Isoelectric Point: 6.2773

>NTDB_id=1138659 DQM55_RS02785 WP_002926514.1 541541..543394(+) (stkP) [Streptococcus sanguinis strain NCTC11086]
MIQIGKIFAGRYKIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREAKAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKENSPISNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNVLLTPDGNAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIISENPNVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSSLSYERRNEKKLVFDDVAKADTKTLPKISPVPQPAVPPVKPTPAKTEAD
EVKEETADAVKKVPKKRRLRTRYKVLFFAVLLVLAAFVVLLYNSPSNTSVPDVSGQTVAEARSAIEAKKLVVGEEKEEYS
DNVESGKVIKTDPQANSQRREGSKIDLIISKGPKTFVMEDYVGQAKSAVVENLKTNYNVSEKLIEIVEEESDEYEPGQVI
RQSPAAGSTYDLTSNHKIKLTVAKEVTSVSMPDFGSMQYTYANARSYLIQMGISSSRIERVVDRSVTSTQADLVTSQSPA
AGQTIDLKSNEKITLYVTEATTPSSSSSSSSSSSSSSKSSSSSEDNGHGTSSSSSDS

Nucleotide


Download         Length: 1854 bp        

>NTDB_id=1138659 DQM55_RS02785 WP_002926514.1 541541..543394(+) (stkP) [Streptococcus sanguinis strain NCTC11086]
ATGATTCAAATCGGCAAAATCTTTGCCGGGCGATATAAAATCATCAAGCAGATTGGCCGTGGAGGCATGGCAGATGTCTA
TTTGGCCAAGGACTTGATTTTGGATGGTGAGGAAGTTGCGGTAAAGGTTCTTAGAACCAATTACCAGACAGATCCTATCG
CTGTCGCGCGTTTCCAGCGGGAAGCCAAGGCGATGGCTGACTTGGACCATCCGCACATCGTTCGGATTACTGATATTGGG
GAAGAAGATGGCCAGCAGTATCTGGCTATGGAATACGTGGCAGGTCTTGACCTCAAGCGCTATATCAAAGAGAATTCTCC
GATTTCAAATGAAGAAGCAGTCAGAATCATGGGACAAATCTTGCTGGCAATGCGCTTAGCGCATACACGCGGTATTGTCC
ATCGTGACCTGAAACCACAAAATGTCCTCTTAACCCCGGATGGCAATGCCAAGGTAACAGACTTTGGGATTGCGGTGGCC
TTTGCAGAGACAAGTCTGACTCAGACTAACTCTATGCTGGGCTCGGTTCATTATCTATCGCCTGAGCAGGCACGTGGCTC
TAAAGCAACTGTTCAGAGTGATATTTATGCGATGGGGATTATTTTTTATGAAATGCTGACTGGTCATATCCCTTATGATG
GGGATAGTGCCGTTACGATTGCCCTGCAGCATTTCCAAAAGCCGCTGCCATCCATCATTTCTGAAAATCCTAATGTGCCT
CAAGCCCTGGAAAATGTGGTCATTAAGGCAACAGCCAAAAAACTGACGGATCGCTATCAGTCGGTTGCAGAGATGTATGT
TGACTTGTCTAGCAGCTTATCCTACGAGCGCCGCAATGAAAAGAAATTAGTCTTTGATGATGTTGCGAAAGCAGACACCA
AGACCTTGCCAAAAATCTCACCTGTACCGCAGCCAGCAGTTCCACCTGTTAAGCCAACTCCGGCTAAAACGGAAGCGGAT
GAAGTTAAGGAAGAGACAGCTGATGCGGTTAAGAAAGTTCCAAAGAAACGTCGCTTGAGAACGCGTTATAAAGTACTTTT
CTTTGCAGTCTTATTGGTTTTGGCCGCCTTTGTCGTCCTTCTCTATAACAGCCCATCTAATACCAGCGTGCCAGATGTTT
CTGGTCAGACTGTAGCAGAGGCTCGTTCTGCTATCGAAGCTAAGAAGCTGGTTGTCGGAGAGGAAAAGGAAGAATACAGC
GACAATGTCGAATCTGGTAAAGTCATTAAAACCGATCCACAGGCCAACAGTCAGCGCCGCGAAGGCAGCAAAATTGACCT
GATTATCTCCAAGGGACCCAAGACCTTTGTAATGGAAGATTATGTCGGTCAAGCAAAATCGGCCGTAGTTGAAAATCTGA
AAACAAACTATAATGTTTCTGAGAAATTGATTGAGATTGTTGAGGAGGAATCGGACGAGTACGAGCCAGGTCAGGTCATT
CGTCAGTCTCCGGCAGCTGGTTCGACTTATGATTTGACTTCTAATCATAAGATCAAGCTGACAGTGGCCAAAGAAGTAAC
TAGTGTGTCCATGCCTGACTTTGGCAGCATGCAGTACACCTACGCCAATGCTCGTTCTTACCTGATTCAAATGGGAATTT
CTTCTTCTCGAATTGAACGAGTTGTTGACCGTTCGGTCACTTCGACTCAGGCAGACTTGGTAACTTCCCAGTCACCAGCG
GCAGGTCAGACAATTGACCTCAAATCTAATGAAAAAATCACTCTTTACGTGACAGAAGCAACAACACCATCGTCATCTAG
CTCGTCATCTTCATCATCTAGTAGCAGCTCAAAGAGCAGCTCATCGTCTGAAGATAACGGACATGGAACTAGTTCCAGTT
CATCTGATAGTTGA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-232)

PASTA domain (PASTA)

(510-578)

PASTA domain (PASTA)

(437-504)

PASTA domain (PASTA)

(370-431)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

63.427

98.379

0.624
  stkP Streptococcus pneumoniae D39

63.097

98.379

0.621
  stkP Streptococcus pneumoniae R6

63.097

98.379

0.621
  stkP Streptococcus pneumoniae Rx1

62.932

98.379

0.619
  pknB Streptococcus mutans UA159

58.092

95.138

0.553
  stkP/pknB Streptococcus salivarius strain HSISS4

56.134

96.434

0.541

Multiple sequence alignment