Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   DQM53_RS03435 Genome accession   NZ_LS483361
Coordinates   620475..621185 (+) Length   236 a.a.
NCBI ID   WP_003049952.1    Uniprot ID   A0A9X9SIG1
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC6179     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 615475..626185
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM53_RS03415 (NCTC6179_00695) - 617259..617891 (-) 633 WP_111715701.1 amino acid ABC transporter permease -
  DQM53_RS03420 (NCTC6179_00696) - 617906..618607 (-) 702 WP_111715704.1 amino acid ABC transporter permease -
  DQM53_RS03425 (NCTC6179_00697) - 618621..619421 (-) 801 WP_111715707.1 transporter substrate-binding domain-containing protein -
  DQM53_RS03430 (NCTC6179_00698) - 619421..620215 (-) 795 WP_003057217.1 amino acid ABC transporter ATP-binding protein -
  DQM53_RS03435 (NCTC6179_00699) vicR 620475..621185 (+) 711 WP_003049952.1 response regulator YycF Regulator
  DQM53_RS03440 (NCTC6179_00700) vicK 621178..622530 (+) 1353 WP_003049953.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQM53_RS03445 (NCTC6179_00701) vicX 622534..623343 (+) 810 WP_003059746.1 MBL fold metallo-hydrolase Regulator
  DQM53_RS03450 (NCTC6179_00702) - 624020..625195 (-) 1176 WP_111715620.1 IS256-like element ISSdy3 family transposase -
  DQM53_RS03455 (NCTC6179_00703) rnc 625421..626113 (+) 693 WP_003057240.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27029.90 Da        Isoelectric Point: 4.9981

>NTDB_id=1138518 DQM53_RS03435 WP_003049952.1 620475..621185(+) (vicR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6179]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTVFEDEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFVAKKHGKEVE
LTHREFELLHHLANHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1138518 DQM53_RS03435 WP_003049952.1 620475..621185(+) (vicR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6179]
ATGAAAAAAATACTGATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAACTTGACAAAAGAAGGTTATGA
CATTGTGACCGCTTTTGATGGCCGTGAAGCTGTTACCGTGTTTGAAGACGAAAAACCGGATTTAATTATTCTTGATTTGA
TGTTACCGGAATTGGACGGTCTTGAAGTGGCCAAAGAAATCCGTAAAACCAGTCATGTGCCGATTATTATGCTGTCGGCT
AAGGATAGTGAGTTTGACAAGGTCATTGGTCTTGAAATTGGGGCAGATGATTATGTTACCAAACCCTTTTCAAATCGTGA
ACTATTAGCGCGTGTCAAGGCTCATTTACGTCGAACAGAAACGATCGAAACAGCCGTAGCAGAGGAAAATGCTTCTTCAG
GTTCACAAGAGTTAACCATTGGTAATTTACAAATTTTACCAGATGCTTTTGTGGCTAAAAAACATGGCAAAGAAGTGGAA
TTAACCCATCGTGAATTTGAATTATTACACCACCTGGCCAATCATATGGGTCAAGTGATGACACGAGAGCACTTGCTTGA
GACGGTTTGGGGCTATGATTACTTTGGCGATGTCCGTACTGTTGACGTGACGGTTCGTCGTCTGCGTGAAAAAATTGAAG
ACACACCAAGCCGTCCCGAATATATTTTAACGAGACGCGGTGTTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.487

99.153

0.788
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

37.712

100

0.377

Multiple sequence alignment