Detailed information NTG1138495

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: DQM53_RS00345
• Genome accession: NZ_LS483361
• Coordinates: 54910..55821 (+)
• Length: 303 a.a.
• NCBI ID: WP_111714689.1
• Uniprot ID: A0A9X8SXJ1
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC6179
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 49910..60821

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM53_RS00325 (NCTC6179_00065)	purD	50233..51495 (+)	1263	WP_111714682.1	phosphoribosylamine--glycine ligase	-
DQM53_RS00330 (NCTC6179_00066)	purE	51896..52384 (+)	489	WP_102776662.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
DQM53_RS00335 (NCTC6179_00067)	purK	52371..53465 (+)	1095	WP_111714684.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
DQM53_RS00340 (NCTC6179_00068)	purB	53475..54767 (+)	1293	WP_111714687.1	adenylosuccinate lyase	-
DQM53_RS00345 (NCTC6179_00069)	comR	54910..55821 (+)	912	WP_111714689.1	XRE family transcriptional regulator	Regulator
DQM53_RS11285 (NCTC6179_00070)	comS	55908..56006 (+)	99	WP_014611913.1	quorum-sensing system DWW-type pheromone	Regulator
DQM53_RS00350 (NCTC6179_00071)	ruvB	56040..57038 (+)	999	WP_111714692.1	Holliday junction branch migration DNA helicase RuvB	-
DQM53_RS00355 (NCTC6179_00072)	-	57173..57604 (+)	432	WP_111714695.1	low molecular weight protein-tyrosine-phosphatase	-
DQM53_RS00360 (NCTC6179_00073)	-	57633..58034 (+)	402	WP_111714697.1	MORN repeat-containing protein	-
DQM53_RS00365 (NCTC6179_00074)	-	58031..59806 (+)	1776	WP_111714700.1	acyltransferase family protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35895.50 Da
• Isoelectric Point: 4.7310

>NTDB_id=1138495 DQM53_RS00345 WP_111714689.1 54910..55821(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6179]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDGKLQVRESQFDEIFENYYDQLPEEEKIAIDIIQAKFEVYQTGDINFGFNILKEFLPQLKKKTVYNLNE
LLLIDLYLIILVVSNFTNDLFNEEFYKEITERILEQHQYLLLEDLFLLNNILLSCADTSIRLKMFERLKDTLQLSHFIMS
TIQDFQRMPMYCMYEWKLSIFYLKDIKRAETYFSQSLTFTQMTNDSYLAQKLQKEWDKDIHPS

Nucleotide

• Length: 912 bp

>NTDB_id=1138495 DQM53_RS00345 WP_111714689.1 54910..55821(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6179]
ATGTTAGAGCATTTTGGTGAAAAAGTGAGAGGACTAAGACTTGAGAAAGGGATTAGTCGAGAGGAATTGTGTGGAGATGA
GGCAGAATTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGTCAATCTATACCAAGCTTAGCGAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGCGTCGGTTATTTGACGGATGGCGCTAACCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTCATTTTAAGGACTCCGACTTATATGGACGATGGCAAATTACAGGTCCGAGAGTCTCAGTTTGATGAGATATTTGA
AAACTATTATGATCAATTGCCCGAGGAGGAAAAAATAGCGATTGATATTATCCAGGCAAAATTTGAAGTTTATCAGACAG
GTGATATTAATTTTGGTTTTAATATTTTAAAAGAATTTCTACCACAACTAAAAAAGAAAACGGTTTATAACTTAAATGAA
TTATTATTAATTGATTTATATTTAATTATTTTAGTTGTTTCTAACTTTACAAATGACCTATTTAATGAGGAATTTTATAA
AGAAATAACGGAGCGAATCTTAGAACAGCATCAGTACCTGTTATTAGAAGATTTATTTCTATTAAATAATATTCTTTTAT
CTTGCGCAGATACTTCTATTCGTTTAAAAATGTTTGAACGACTAAAGGATACGTTACAACTCAGCCATTTTATTATGTCA
ACCATTCAAGATTTTCAGCGAATGCCCATGTATTGCATGTATGAATGGAAATTATCTATCTTTTATTTAAAAGATATTAA
ACGAGCAGAAACTTATTTTAGTCAATCTCTCACGTTTACTCAAATGACTAATGATAGTTATTTGGCACAAAAGCTTCAAA
AAGAATGGGATAAGGATATTCATCCCTCTTAA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (12-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	83.389	99.34	0.828
comR	Streptococcus pyogenes MGAS8232	55.629	99.67	0.554
comR	Streptococcus mutans UA159	45.819	98.68	0.452
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	46.575	96.37	0.449