Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DQL13_RS08545 Genome accession   NZ_LS483354
Coordinates   1795562..1796326 (-) Length   254 a.a.
NCBI ID   WP_012516292.1    Uniprot ID   B4U4W9
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC11606     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1790562..1801326
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL13_RS08525 (NCTC11606_01706) - 1790900..1792126 (-) 1227 WP_111721735.1 cysteine desulfurase -
  DQL13_RS08530 (NCTC11606_01707) sufD 1792153..1793415 (-) 1263 WP_111721736.1 Fe-S cluster assembly protein SufD -
  DQL13_RS08535 (NCTC11606_01708) sufC 1793507..1794277 (-) 771 WP_012516290.1 Fe-S cluster assembly ATPase SufC -
  DQL13_RS08540 (NCTC11606_01709) - 1794398..1795555 (-) 1158 WP_041785937.1 glycosyltransferase family 4 protein -
  DQL13_RS08545 (NCTC11606_01710) mecA 1795562..1796326 (-) 765 WP_012516292.1 adaptor protein MecA Regulator
  DQL13_RS08550 (NCTC11606_01711) - 1796446..1797285 (-) 840 WP_012516293.1 undecaprenyl-diphosphate phosphatase -
  DQL13_RS08555 (NCTC11606_01712) - 1797600..1799168 (+) 1569 WP_012516295.1 ABC transporter substrate-binding protein/permease -
  DQL13_RS08560 (NCTC11606_01713) - 1799161..1799901 (+) 741 WP_012680102.1 amino acid ABC transporter ATP-binding protein -
  DQL13_RS08565 (NCTC11606_01714) - 1800224..1800340 (+) 117 WP_012677375.1 putative metal homeostasis protein -

Sequence

Protein


Download         Length: 254 a.a.        Molecular weight: 29277.10 Da        Isoelectric Point: 4.2228

>NTDB_id=1138184 DQL13_RS08545 WP_012516292.1 1795562..1796326(-) (mecA) [Streptococcus equi subsp. zooepidemicus strain NCTC11606]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDL
NKDLNFEDLADLGDISQMTPEDFFRSLEQSMREKGDVNAHEKLEKIEEIMEDVVDATLAEQADNKEAAELDEPTEPLDYV
HYVLDFASVRDAVCFAKVIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARLIEHASPGTKTRAYLQEHGCQLI
FDGAVEELQKIRLG

Nucleotide


Download         Length: 765 bp        

>NTDB_id=1138184 DQL13_RS08545 WP_012516292.1 1795562..1796326(-) (mecA) [Streptococcus equi subsp. zooepidemicus strain NCTC11606]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGGGGGATGGAGCT
CAAGGACTTCTTGATCCCTCAAGAAAAGACAGAGGAGTTCTTTTATGCTGTCATGGACGAGTTGGACCTTCCGGACAATT
TTAAGGACAGTGGTATGCTTAGCTTTCGAGTGACTCCAAGAAAGGATCGCTTAGATGTTTTTGTGACCAAATCAGACCTC
AATAAGGACCTTAATTTTGAGGATTTGGCAGACCTAGGTGATATTTCTCAAATGACTCCAGAGGATTTTTTCAGAAGCTT
GGAGCAGTCTATGCGTGAAAAGGGTGATGTCAATGCCCATGAAAAGCTTGAAAAAATCGAGGAGATCATGGAGGACGTGG
TTGATGCTACCTTGGCTGAGCAAGCAGATAATAAGGAAGCTGCTGAGCTTGATGAGCCGACAGAGCCACTTGATTATGTT
CACTATGTTCTTGATTTTGCTTCTGTTCGAGACGCTGTTTGCTTTGCTAAGGTGATTGATTTTCCGATCGAGGCTTCTGA
ATTGTATAAGGGTCCTCGTCATTATCACATGACGATTTTACTTGATGTGCAAAACAAGCCTGCCTACTTTGCCAATGTGA
TGTATGCCAGATTGATTGAGCATGCTAGTCCTGGTACAAAAACAAGAGCTTATTTGCAGGAGCATGGTTGTCAGCTCATT
TTTGATGGTGCTGTTGAGGAGCTACAAAAAATCAGGTTGGGGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B4U4W9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.745

98.819

0.63
  mecA Streptococcus thermophilus LMD-9

57.255

100

0.575
  mecA Streptococcus thermophilus LMG 18311

56.471

100

0.567
  mecA Streptococcus pneumoniae TIGR4

48.031

100

0.48
  mecA Streptococcus pneumoniae Rx1

47.638

100

0.476
  mecA Streptococcus pneumoniae D39

47.638

100

0.476
  mecA Streptococcus pneumoniae R6

47.638

100

0.476

Multiple sequence alignment