Detailed information NTG1138157

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: DQL13_RS04740
• Genome accession: NZ_LS483354
• Coordinates: 1000026..1000700 (+)
• Length: 224 a.a.
• NCBI ID: WP_012515548.1
• Uniprot ID: B4U2R0
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC11606
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 995026..1005700

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL13_RS04725 (NCTC11606_00942)	pstB	995346..996104 (+)	759	WP_012678019.1	phosphate ABC transporter ATP-binding protein PstB	-
DQL13_RS04730 (NCTC11606_00943)	phoU	996175..996828 (+)	654	WP_012678018.1	phosphate signaling complex protein PhoU	-
DQL13_RS04735 (NCTC11606_00944)	-	997062..999599 (+)	2538	WP_111721676.1	M1 family metallopeptidase	-
DQL13_RS04740 (NCTC11606_00945)	ciaR	1000026..1000700 (+)	675	WP_012515548.1	response regulator transcription factor	Regulator
DQL13_RS04745 (NCTC11606_00946)	ciaH	1000693..1002003 (+)	1311	WP_012515549.1	sensor histidine kinase	Regulator
DQL13_RS04750 (NCTC11606_00947)	-	1002388..1002819 (+)	432	WP_012515550.1	hypothetical protein	-
DQL13_RS09870	-	1002901..1003077 (+)	177	WP_012515551.1	hypothetical protein	-
DQL13_RS04755 (NCTC11606_00948)	-	1003250..1003633 (+)	384	WP_012515552.1	hypothetical protein	-
DQL13_RS04760 (NCTC11606_00949)	-	1003630..1003890 (+)	261	WP_012515553.1	hypothetical protein	-
DQL13_RS04765 (NCTC11606_00950)	-	1003906..1004319 (+)	414	WP_012515554.1	hypothetical protein	-
DQL13_RS04775 (NCTC11606_00952)	-	1004534..1004929 (+)	396	WP_012515555.1	hypothetical protein	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25541.52 Da
• Isoelectric Point: 4.5644

>NTDB_id=1138157 DQL13_RS04740 WP_012515548.1 1000026..1000700(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain NCTC11606]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTA
KESIDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQAIELLGKELDLLIY
ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGYILKANE

Nucleotide

• Length: 675 bp

>NTDB_id=1138157 DQL13_RS04740 WP_012515548.1 1000026..1000700(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain NCTC11606]
ATGATAAAACTATTATTAGTAGAAGACGATTTAAGCTTGTCAAATTCTATCTTTGATTTTTTAGATGACTTTGCTGATGT
GACGCAGGTTTTTGATGGTGACGAAGGACTCTATGAGGCAGAAAGCGGTATTTATGATTTGATTCTGTTAGATTTGATGC
TGCCTGAAAAGGATGGCTTTCAAGTGTTAAAAGCCTTACGTGAAAAAGACATCAAAATTCCCGTCTTGATCATGACTGCC
AAAGAAAGCATCGATGACAAAGGGCATGGCTTTGAGCTTGGTGCTGATGACTATTTAACCAAGCCCTTTTACCTAGAAGA
ATTAAAAATGCGGATTCAGGCCTTGCTTAAGCGCGTAGGAAAGTTTAATGATAAGAGCCTTAAATTTGGCAACTTGACTG
TAGATACTACCCGTAAAGAGGTACAGGTCAATGGGCAGGCCATAGAGCTATTAGGCAAGGAGCTTGATTTACTAATCTAT
ATCCTTCAAAATCAAAATGTTATTTTGCCAAAATCACAAATTTTTGATCGTATCTGGGGCTTTGATAGTGATACCACTAT
CTCTGTTGTAGAGGTCTATGTCTCTAAAATTCGTAAGAAGCTTAAGGGGACAGACTTTGTTAATCATCTTCAAACCTTGA
GAAGTGTAGGATATATCTTAAAAGCTAATGAATAA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (5-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	84.615	98.661	0.835
ciaR	Streptococcus pneumoniae Rx1	80.543	98.661	0.795
ciaR	Streptococcus pneumoniae D39	80.543	98.661	0.795
ciaR	Streptococcus pneumoniae R6	80.543	98.661	0.795
ciaR	Streptococcus pneumoniae TIGR4	80.543	98.661	0.795
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.428	100	0.393
covR	Streptococcus salivarius strain HSISS4	35.841	100	0.362