Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DQM48_RS01605 Genome accession   NZ_LS483348
Coordinates   284856..285617 (+) Length   253 a.a.
NCBI ID   WP_020916168.1    Uniprot ID   A0AB33AJT1
Organism   Streptococcus lutetiensis strain NCTC8738     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 279856..290617
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM48_RS01590 (NCTC8738_00321) - 280261..281832 (-) 1572 WP_111698221.1 ABC transporter substrate-binding protein/permease -
  DQM48_RS01595 (NCTC8738_00322) - 281969..283861 (+) 1893 WP_172454523.1 DUF2207 domain-containing protein -
  DQM48_RS01600 (NCTC8738_00323) - 283913..284752 (+) 840 WP_020916167.1 undecaprenyl-diphosphate phosphatase -
  DQM48_RS01605 (NCTC8738_00324) mecA 284856..285617 (+) 762 WP_020916168.1 adaptor protein MecA Regulator
  DQM48_RS01610 (NCTC8738_00325) - 285619..286782 (+) 1164 WP_020916169.1 glycosyltransferase family 4 protein -
  DQM48_RS01615 (NCTC8738_00326) sufC 286896..287666 (+) 771 WP_020916170.1 Fe-S cluster assembly ATPase SufC -
  DQM48_RS01620 (NCTC8738_00327) sufD 287741..289003 (+) 1263 WP_020916171.1 Fe-S cluster assembly protein SufD -
  DQM48_RS01625 (NCTC8738_00328) - 289005..290237 (+) 1233 WP_058833245.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29223.91 Da        Isoelectric Point: 3.9687

>NTDB_id=1137807 DQM48_RS01605 WP_020916168.1 284856..285617(+) (mecA) [Streptococcus lutetiensis strain NCTC8738]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRIDVFVTKSEI
NKDINFEDLAAFDDVSNMSPEEFFKTLEQTMLSKDDTEAHEKLGEIEEMMEGAVEDVLTEHAQQAEIEPEEDVNPSDYVH
YVLDFPSLEAAVAFAKVIDFPVEASEFYKMDGTYYMTVLIDLQNHPSYYANLMYARMLEYAGAGTKTRAYLQEHAVELLT
DDAVEKLKMIELV

Nucleotide


Download         Length: 762 bp        

>NTDB_id=1137807 DQM48_RS01605 WP_020916168.1 284856..285617(+) (mecA) [Streptococcus lutetiensis strain NCTC8738]
ATGGAAATGAAACAGATTAGCGAGACAACGCTAAAAATAACGATTAGTATGGAAGATTTAGAAGAACGCGGAATGGAGTT
GAAAGACTTCTTGATTCCACAAGAAAAGACAGAAGAGTTCTTCTATTCAGTAATGGATGAATTGGATTTACCAGATAATT
TCAAAGACAGTGGCATGCTTAGTTTCCGTGTGACACCACGTAAAGACCGTATTGATGTCTTTGTTACCAAATCTGAAATC
AATAAAGATATAAACTTTGAAGATTTAGCAGCTTTTGATGATGTTTCAAATATGTCACCTGAGGAATTTTTCAAGACTTT
AGAGCAGACAATGCTGTCTAAAGACGACACGGAAGCTCACGAAAAATTAGGTGAGATTGAAGAAATGATGGAAGGTGCTG
TTGAAGATGTTCTGACAGAACATGCCCAACAAGCTGAGATTGAACCGGAAGAAGATGTGAATCCATCAGATTATGTTCAC
TATGTCTTGGATTTTCCAAGCTTAGAAGCTGCTGTTGCTTTTGCTAAGGTTATTGATTTTCCAGTTGAAGCTTCAGAGTT
TTATAAGATGGATGGGACTTACTACATGACAGTTCTTATTGATTTGCAAAATCATCCTTCTTATTATGCAAATTTGATGT
ATGCCCGTATGTTAGAATACGCTGGCGCTGGTACAAAAACGCGTGCTTATTTACAAGAGCATGCGGTTGAATTATTGACG
GATGATGCTGTCGAAAAATTAAAAATGATTGAGTTGGTATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

66.8

98.814

0.66
  mecA Streptococcus thermophilus LMD-9

59.438

98.419

0.585
  mecA Streptococcus thermophilus LMG 18311

58.635

98.419

0.577
  mecA Streptococcus pneumoniae Rx1

49.02

100

0.494
  mecA Streptococcus pneumoniae D39

49.02

100

0.494
  mecA Streptococcus pneumoniae R6

49.02

100

0.494
  mecA Streptococcus pneumoniae TIGR4

49.02

100

0.494

Multiple sequence alignment