Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   DQM73_RS09465 Genome accession   NZ_LS483346
Coordinates   1901307..1903160 (-) Length   617 a.a.
NCBI ID   WP_002926514.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC11085     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1896307..1908160
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM73_RS09440 (NCTC11085_01855) - 1897038..1897400 (-) 363 WP_002926507.1 S1 RNA-binding domain-containing protein -
  DQM73_RS09445 (NCTC11085_01856) - 1897400..1898800 (-) 1401 WP_002934595.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQM73_RS09450 (NCTC11085_01857) - 1898840..1899472 (-) 633 WP_002926512.1 response regulator transcription factor -
  DQM73_RS09455 (NCTC11085_01858) - 1899450..1900469 (-) 1020 WP_002926513.1 sensor histidine kinase -
  DQM73_RS09460 (NCTC11085_01859) liaF 1900466..1901161 (-) 696 WP_002893496.1 cell wall-active antibiotics response protein LiaF -
  DQM73_RS09465 (NCTC11085_01860) stkP 1901307..1903160 (-) 1854 WP_002926514.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DQM73_RS09470 (NCTC11085_01861) - 1903157..1903897 (-) 741 WP_002926516.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DQM73_RS09475 (NCTC11085_01862) rsmB 1903916..1905232 (-) 1317 WP_002926518.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  DQM73_RS09480 (NCTC11085_01863) fmt 1905222..1906157 (-) 936 WP_002926520.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 617 a.a.        Molecular weight: 67427.26 Da        Isoelectric Point: 6.2773

>NTDB_id=1137714 DQM73_RS09465 WP_002926514.1 1901307..1903160(-) (stkP) [Streptococcus sanguinis strain NCTC11085]
MIQIGKIFAGRYKIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREAKAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKENSPISNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNVLLTPDGNAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIISENPNVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSSLSYERRNEKKLVFDDVAKADTKTLPKISPVPQPAVPPVKPTPAKTEAD
EVKEETADAVKKVPKKRRLRTRYKVLFFAVLLVLAAFVVLLYNSPSNTSVPDVSGQTVAEARSAIEAKKLVVGEEKEEYS
DNVESGKVIKTDPQANSQRREGSKIDLIISKGPKTFVMEDYVGQAKSAVVENLKTNYNVSEKLIEIVEEESDEYEPGQVI
RQSPAAGSTYDLTSNHKIKLTVAKEVTSVSMPDFGSMQYTYANARSYLIQMGISSSRIERVVDRSVTSTQADLVTSQSPA
AGQTIDLKSNEKITLYVTEATTPSSSSSSSSSSSSSSKSSSSSEDNGHGTSSSSSDS

Nucleotide


Download         Length: 1854 bp        

>NTDB_id=1137714 DQM73_RS09465 WP_002926514.1 1901307..1903160(-) (stkP) [Streptococcus sanguinis strain NCTC11085]
ATGATTCAAATCGGCAAAATCTTTGCCGGGCGATATAAAATCATCAAGCAGATTGGCCGTGGAGGCATGGCAGATGTCTA
TTTGGCCAAGGACTTGATTTTGGATGGTGAGGAAGTTGCGGTAAAGGTTCTTAGAACCAATTACCAGACAGATCCTATCG
CTGTCGCGCGTTTCCAGCGGGAAGCCAAGGCGATGGCTGACTTGGACCATCCGCACATCGTTCGGATTACTGATATTGGG
GAAGAAGATGGCCAGCAGTATCTGGCTATGGAATACGTGGCAGGTCTTGACCTCAAGCGCTATATCAAAGAGAATTCTCC
GATTTCAAATGAAGAAGCAGTCAGAATCATGGGACAAATCTTGCTGGCAATGCGCTTAGCGCATACACGCGGTATTGTCC
ATCGTGACCTGAAACCACAAAATGTCCTCTTAACCCCGGATGGCAATGCCAAGGTAACAGACTTTGGGATTGCGGTGGCC
TTTGCAGAGACAAGTCTGACTCAGACTAACTCTATGCTGGGCTCGGTTCATTATCTATCGCCTGAGCAGGCACGTGGCTC
TAAAGCAACTGTTCAGAGTGATATTTATGCGATGGGGATTATTTTTTATGAAATGCTGACTGGTCATATCCCTTATGATG
GGGATAGTGCCGTTACGATTGCCCTGCAGCATTTCCAAAAGCCGCTGCCATCCATCATTTCTGAAAATCCTAATGTGCCT
CAAGCCCTGGAAAATGTGGTCATTAAGGCAACAGCCAAAAAACTGACGGATCGCTATCAGTCGGTTGCAGAGATGTATGT
TGACTTGTCTAGCAGCTTATCCTACGAGCGCCGCAATGAAAAGAAATTAGTCTTTGATGATGTTGCGAAAGCAGACACCA
AGACCTTGCCAAAAATCTCACCTGTACCGCAGCCAGCAGTTCCACCTGTTAAGCCAACTCCGGCTAAAACGGAAGCGGAT
GAAGTTAAGGAAGAGACAGCTGATGCGGTTAAGAAAGTTCCAAAGAAACGTCGCTTGAGAACGCGTTATAAAGTACTTTT
CTTTGCAGTCTTATTGGTTTTGGCCGCCTTTGTCGTCCTTCTCTATAACAGCCCATCTAATACCAGCGTGCCAGATGTTT
CTGGTCAGACTGTAGCAGAGGCTCGTTCTGCTATCGAAGCTAAGAAGCTGGTTGTCGGAGAGGAAAAGGAAGAATACAGC
GACAATGTCGAATCTGGTAAAGTCATTAAAACCGATCCACAGGCCAACAGTCAGCGCCGCGAAGGCAGCAAAATTGACCT
GATTATCTCCAAGGGACCCAAGACCTTTGTAATGGAAGATTATGTCGGTCAAGCAAAATCGGCCGTAGTTGAAAATCTGA
AAACAAACTATAATGTTTCTGAGAAATTGATTGAGATTGTTGAGGAGGAATCGGACGAGTACGAGCCAGGTCAGGTCATT
CGTCAGTCTCCGGCAGCTGGTTCGACTTATGATTTGACTTCTAATCATAAGATCAAGCTGACAGTGGCCAAAGAAGTAAC
TAGTGTGTCCATGCCTGACTTTGGCAGCATGCAGTACACCTACGCCAATGCTCGTTCTTACCTGATTCAAATGGGAATTT
CTTCTTCTCGAATTGAACGAGTTGTTGACCGTTCGGTCACTTCGACTCAGGCAGACTTGGTAACTTCCCAGTCACCAGCG
GCAGGTCAGACAATTGACCTCAAATCTAATGAAAAAATCACTCTTTACGTGACAGAAGCAACAACACCATCGTCATCTAG
CTCGTCATCTTCATCATCTAGTAGCAGCTCAAAGAGCAGCTCATCGTCTGAAGATAACGGACATGGAACTAGTTCCAGTT
CATCTGATAGTTGA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-232)

PASTA domain (PASTA)

(510-578)

PASTA domain (PASTA)

(437-504)

PASTA domain (PASTA)

(370-431)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

63.427

98.379

0.624
  stkP Streptococcus pneumoniae D39

63.097

98.379

0.621
  stkP Streptococcus pneumoniae R6

63.097

98.379

0.621
  stkP Streptococcus pneumoniae Rx1

62.932

98.379

0.619
  pknB Streptococcus mutans UA159

58.092

95.138

0.553
  stkP/pknB Streptococcus salivarius strain HSISS4

56.134

96.434

0.541

Multiple sequence alignment