Detailed information NTG1137653

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQL69_RS04355
• Genome accession: NZ_LS483345
• Coordinates: 857937..858773 (-)
• Length: 278 a.a.
• NCBI ID: WP_047235811.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8231
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 852937..863773

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL69_RS04330 (NCTC8231_00854)	-	853157..854149 (-)	993	WP_047235809.1	D-lactate dehydrogenase	-
DQL69_RS04335 (NCTC8231_00855)	-	854164..854730 (-)	567	Protein_771	PTS sugar transporter subunit IIC	-
DQL69_RS09095	-	854770..855627 (+)	858	Protein_772	LysR family transcriptional regulator	-
DQL69_RS04350 (NCTC8231_00857)	topA	855702..857831 (-)	2130	WP_047235810.1	type I DNA topoisomerase	-
DQL69_RS04355 (NCTC8231_00858)	dprA	857937..858773 (-)	837	WP_047235811.1	DNA-processing protein DprA	Machinery gene
DQL69_RS04360 (NCTC8231_00859)	-	858838..859629 (-)	792	WP_002995007.1	ribonuclease HII	-
DQL69_RS04365 (NCTC8231_00860)	ylqF	859619..860467 (-)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
DQL69_RS04370 (NCTC8231_00861)	-	860686..861126 (+)	441	WP_011017769.1	DUF1836 domain-containing protein	-
DQL69_RS04375 (NCTC8231_00862)	trhA	861123..861773 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQL69_RS04380 (NCTC8231_00863)	-	861890..862801 (+)	912	WP_047235812.1	diacylglycerol/lipid kinase family protein	-
DQL69_RS04385 (NCTC8231_00864)	-	862851..863225 (-)	375	WP_111690759.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30993.02 Da
• Isoelectric Point: 9.2511

>NTDB_id=1137653 DQL69_RS04355 WP_047235811.1 857937..858773(-) (dprA) [Streptococcus pyogenes strain NCTC8231]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIISGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1137653 DQL69_RS04355 WP_047235811.1 857937..858773(-) (dprA) [Streptococcus pyogenes strain NCTC8231]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTATTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae D39	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae R6	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	59.712	100	0.597
dprA/cilB/dalA	Streptococcus mitis SK321	59.712	100	0.597
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.353	100	0.594
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	100	0.568