Detailed information NTG1137489

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: DQL23_RS04665
• Genome accession: NZ_LS483341
• Coordinates: 980874..983114 (+)
• Length: 746 a.a.
• NCBI ID: WP_060554136.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain NCTC7865
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 975874..988114

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL23_RS04645 (NCTC7865_00931)	-	976323..978692 (-)	2370	WP_060554132.1	cation-translocating P-type ATPase	-
DQL23_RS04650 (NCTC7865_00932)	-	978822..979562 (+)	741	WP_060554133.1	lysophospholipid acyltransferase family protein	-
DQL23_RS04655 (NCTC7865_00933)	-	979601..980128 (+)	528	WP_060554134.1	HXXEE domain-containing protein	-
DQL23_RS04660 (NCTC7865_00934)	comEA/celA/cilE	980225..980890 (+)	666	WP_060554135.1	helix-hairpin-helix domain-containing protein	Machinery gene
DQL23_RS04665 (NCTC7865_00935)	comEC/celB	980874..983114 (+)	2241	WP_060554136.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DQL23_RS04670 (NCTC7865_00936)	holA	983205..984242 (+)	1038	WP_060554137.1	DNA polymerase III subunit delta	-
DQL23_RS04675 (NCTC7865_00937)	-	984315..984920 (+)	606	WP_045503938.1	superoxide dismutase	-
DQL23_RS04680 (NCTC7865_00938)	-	985032..986105 (+)	1074	WP_081041949.1	serine hydrolase	-
DQL23_RS04685 (NCTC7865_00939)	-	986310..987098 (+)	789	WP_060554138.1	YhfC family intramembrane metalloprotease	-
DQL23_RS04690 (NCTC7865_00940)	-	987076..987357 (+)	282	WP_012130660.1	autorepressor SdpR family transcription factor	-
DQL23_RS04695 (NCTC7865_00941)	-	987344..987841 (+)	498	WP_060554139.1	DUF1648 domain-containing protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 85062.93 Da
• Isoelectric Point: 9.8605

>NTDB_id=1137489 DQL23_RS04665 WP_060554136.1 980874..983114(+) (comEC/celB) [Streptococcus gordonii strain NCTC7865]
MSQWIKKLPLSPIYLCFLLVWLYFAIYSGEKLAYLGVFLLIARLIWHYPRKKWLPTLAILACFAIFFYARRELTERTFQS
QPAPARQVLVLPDTIKVNGDSLSFRGRIAGRLYQLYYKLASPREKKTFQKLTDLVTLEIEAEFNLAEGQRNFSGFDYQAY
LKSQGIYRTVKVSGIISSRSSQSANPFDWLSVWRRKALVFIKSTFPSPMSHYMTGLLFGDLDIDFAEMNDLYSSLGIIHL
FALSGMQVGFFMDVFRKILLRIGLRMETVDWLQFPLSFIYAGLTGFSVSVVRSLVQKLLSQFGVRRLDNFAMTMLVLMLL
MPSFLLTTGGVLSCAYAFIITMLDFKDSSGFRKAVLESLSISLGILPILIYYFAEFQPWSILLTFLFSIVFDVFMLPLLS
LIFVLSPLFAITQVNIFFQWLEIVIRWVAGLSTRPIVLGQPNLTLLILLLLALALLYDFRKQKKIKAGLSLLAILLFFLS
KYPLQNEITVVDIGQGDSIFLRDIRGRTIVIDTGGRVEIGKKEAWQERVRKSNAETTLIPYLKSRGVDHLDQLVLTHTDT
DHMGDMLDLAKHFSIREIYVSKGSMTQSDFVGKLKKMKAKVHVVEVGDRLPIFDSALEVLYPLTQGDGGNDDSIVLYGEF
FRTKFLFTGDLEAPGEGQMVTAYPDLRVDVLKAGHHGSKGSSSPEFLEHIKPKLALISAGKNNRYQHPHQETLERFEKIQ
TKILRTDEQGAIRFKGWSSWKIETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1137489 DQL23_RS04665 WP_060554136.1 980874..983114(+) (comEC/celB) [Streptococcus gordonii strain NCTC7865]
ATGTCACAGTGGATTAAAAAACTTCCCCTTTCACCAATCTATTTGTGCTTTCTTTTGGTTTGGCTTTACTTCGCTATTTA
TAGTGGGGAAAAGCTCGCTTATCTGGGAGTTTTTCTGCTTATAGCTCGCCTAATCTGGCATTATCCAAGAAAGAAATGGT
TGCCAACTTTGGCTATCCTAGCCTGTTTTGCTATCTTTTTTTATGCTAGACGCGAGTTGACGGAGCGAACCTTTCAGTCT
CAACCAGCTCCAGCAAGACAAGTCTTAGTTTTACCAGATACAATTAAAGTAAATGGAGATTCCCTGTCATTCCGTGGTAG
AATAGCTGGCAGACTCTATCAGCTCTACTACAAATTAGCAAGTCCAAGAGAGAAAAAAACTTTTCAAAAACTAACTGACT
TGGTCACTTTAGAGATAGAAGCGGAGTTCAATCTAGCAGAAGGACAGCGCAATTTCTCTGGCTTTGACTATCAGGCTTAT
TTAAAAAGTCAGGGAATCTATCGGACGGTTAAGGTCAGTGGGATTATCTCTAGTCGTTCTAGTCAGTCTGCTAATCCATT
TGATTGGCTGTCTGTTTGGCGTAGGAAGGCCTTGGTTTTCATTAAGTCTACTTTTCCAAGCCCGATGAGTCACTACATGA
CAGGACTCTTGTTTGGTGATTTAGATATTGATTTTGCAGAGATGAATGACTTGTACTCAAGTTTAGGAATTATCCATCTT
TTTGCTTTATCAGGAATGCAAGTTGGCTTTTTTATGGATGTCTTTCGAAAAATTCTTCTACGCATTGGCTTAAGAATGGA
AACAGTAGATTGGTTGCAATTCCCTTTGTCCTTTATTTATGCTGGTTTGACCGGATTTTCTGTGTCAGTAGTGAGAAGTT
TAGTGCAAAAGTTGTTGTCTCAATTTGGAGTGAGGCGCTTGGATAATTTTGCGATGACCATGCTGGTCTTAATGCTTCTT
ATGCCAAGCTTTCTCCTGACAACAGGCGGAGTCCTATCTTGCGCTTATGCCTTTATCATCACGATGTTGGACTTTAAAGA
TTCTAGTGGTTTTCGCAAAGCAGTGCTAGAGAGTTTAAGCATCTCGCTAGGTATTTTACCAATTCTTATCTATTATTTTG
CAGAATTCCAGCCTTGGTCTATCCTCTTGACCTTCCTTTTTTCAATCGTTTTTGATGTATTTATGTTGCCTCTCTTGAGT
CTAATTTTTGTCCTTTCGCCTTTGTTTGCCATCACTCAAGTTAATATCTTTTTCCAATGGCTGGAAATAGTTATACGTTG
GGTAGCTGGTCTGTCAACAAGGCCAATAGTTTTAGGTCAGCCCAATCTGACTTTGCTTATTCTTCTTCTACTAGCTTTAG
CCTTACTCTATGATTTTAGAAAACAAAAAAAGATTAAGGCTGGTCTGAGTCTGTTAGCAATCTTGCTATTTTTCCTAAGT
AAATATCCCTTGCAAAATGAAATCACAGTGGTTGATATTGGACAAGGAGATAGTATATTTCTGAGAGATATCAGAGGCCG
AACCATTGTAATTGATACAGGAGGACGGGTGGAGATTGGTAAAAAAGAGGCTTGGCAAGAGCGCGTGAGAAAAAGCAATG
CGGAAACGACCTTAATCCCTTATTTAAAAAGTCGAGGAGTGGATCACTTGGATCAATTAGTCCTGACTCACACAGATACA
GACCATATGGGAGATATGTTGGACTTAGCCAAGCATTTTTCTATCCGAGAAATTTATGTTTCCAAAGGAAGTATGACTCA
GTCTGATTTTGTAGGCAAGTTAAAGAAGATGAAAGCTAAAGTTCATGTAGTCGAGGTGGGAGATCGGCTTCCTATTTTTG
ATTCGGCTCTTGAAGTGCTCTACCCGCTTACTCAAGGAGATGGAGGTAATGATGATTCAATTGTCTTGTATGGTGAATTT
TTCCGGACCAAGTTTCTTTTCACAGGAGATTTAGAAGCTCCAGGTGAAGGTCAGATGGTGACAGCCTATCCAGATTTAAG
AGTAGATGTGCTCAAAGCTGGGCATCATGGTTCTAAAGGATCTTCTAGTCCAGAATTTCTAGAGCATATTAAGCCTAAGT
TGGCCTTGATTTCAGCTGGTAAAAACAATCGCTACCAGCATCCGCATCAGGAAACTTTAGAAAGATTTGAAAAAATCCAG
ACCAAGATTTTACGGACAGATGAGCAGGGTGCTATTCGATTTAAAGGATGGAGTTCTTGGAAGATAGAAACAGTTCGCTA
G

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-460)

• Metallo-beta-lactamase superfamily (Lactamase_B) (494-700)

• Domain of unknown function (DUF4131) (DUF4131) (35-175)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	58.768	100	0.588
comEC/celB	Streptococcus pneumoniae TIGR4	57.965	100	0.58
comEC/celB	Streptococcus mitis NCTC 12261	57.507	100	0.575
comEC/celB	Streptococcus pneumoniae Rx1	57.028	100	0.571
comEC/celB	Streptococcus pneumoniae D39	57.028	100	0.571
comEC/celB	Streptococcus pneumoniae R6	57.028	100	0.571
comEC	Lactococcus lactis subsp. cremoris KW2	50.538	99.732	0.504