Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DQL23_RS04075 Genome accession   NZ_LS483341
Coordinates   852356..853084 (+) Length   242 a.a.
NCBI ID   WP_060553911.1    Uniprot ID   A0AB35FTN8
Organism   Streptococcus gordonii strain NCTC7865     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 847356..858084
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL23_RS04060 (NCTC7865_00811) - 847528..849093 (-) 1566 WP_060553909.1 ABC transporter substrate-binding protein/permease -
  DQL23_RS04065 (NCTC7865_00812) - 849306..851297 (+) 1992 WP_223358713.1 DUF2207 domain-containing protein -
  DQL23_RS04070 (NCTC7865_00813) - 851386..852234 (+) 849 WP_060553910.1 undecaprenyl-diphosphate phosphatase -
  DQL23_RS04075 (NCTC7865_00814) mecA 852356..853084 (+) 729 WP_060553911.1 adaptor protein MecA Regulator
  DQL23_RS04080 (NCTC7865_00815) - 853078..854244 (+) 1167 WP_060553912.1 glycosyltransferase family 4 protein -
  DQL23_RS04085 (NCTC7865_00816) sufC 854331..855101 (+) 771 WP_046164600.1 Fe-S cluster assembly ATPase SufC -
  DQL23_RS04090 (NCTC7865_00817) sufD 855143..856405 (+) 1263 WP_060553913.1 Fe-S cluster assembly protein SufD -
  DQL23_RS04095 (NCTC7865_00818) - 856445..857677 (+) 1233 WP_060553914.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 242 a.a.        Molecular weight: 28232.87 Da        Isoelectric Point: 4.1489

>NTDB_id=1137476 DQL23_RS04075 WP_060553911.1 852356..853084(+) (mecA) [Streptococcus gordonii strain NCTC7865]
MEVKQISESTIKITIKLEDLEEHGMEMADFLVPQEKTEEFFYTILDELEMPESFLDSGMLSFRVTPKPDKLDVFVTKSKV
DKNLNFEDLADLPGMDELSQMTPDEFLKTLEKNIFEKSRDDIDAVQMLEKAEEEDTSEPEEGQEQDRYIYYILRFSDLKN
LIAFTKTVDYPVDTSELYKMDQHYYLTILVDIEGRPSRYPAWLLAAMREHAEDTDTTRALLQEHGHLLIVTDAVQHLQKV
NC

Nucleotide


Download         Length: 729 bp        

>NTDB_id=1137476 DQL23_RS04075 WP_060553911.1 852356..853084(+) (mecA) [Streptococcus gordonii strain NCTC7865]
ATGGAAGTGAAGCAAATTAGTGAATCAACAATCAAGATCACCATCAAATTAGAAGATCTAGAAGAGCATGGTATGGAAAT
GGCTGATTTTCTGGTTCCTCAAGAAAAGACGGAGGAATTTTTCTATACCATTTTGGACGAACTAGAAATGCCAGAAAGCT
TTTTAGATAGTGGAATGCTGAGTTTTCGGGTGACTCCAAAACCAGACAAATTAGACGTTTTTGTCACAAAATCTAAAGTA
GACAAAAATTTAAATTTTGAAGATTTGGCTGACTTGCCTGGTATGGACGAACTTTCTCAAATGACTCCGGATGAATTTCT
AAAGACGCTTGAAAAAAACATCTTTGAAAAAAGCCGTGATGATATAGATGCTGTTCAAATGCTGGAAAAAGCAGAAGAGG
AAGATACATCTGAACCAGAGGAAGGGCAAGAACAAGATCGCTATATTTATTATATCTTGCGTTTTTCTGACTTGAAAAAT
CTGATTGCATTCACCAAAACAGTTGACTATCCGGTGGATACATCAGAGTTATACAAGATGGATCAGCATTACTATTTGAC
TATTTTAGTAGATATTGAAGGTCGTCCGAGTCGTTATCCAGCTTGGCTTCTGGCAGCAATGCGTGAACATGCTGAGGATA
CAGATACGACGAGAGCCCTTCTTCAAGAGCACGGTCACTTGTTGATTGTAACAGATGCTGTGCAACATCTTCAAAAGGTA
AACTGCTGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

65.306

100

0.661
  mecA Streptococcus pneumoniae D39

65.306

100

0.661
  mecA Streptococcus pneumoniae R6

65.306

100

0.661
  mecA Streptococcus pneumoniae TIGR4

65.306

100

0.661
  mecA Streptococcus mutans UA159

52.263

100

0.525
  mecA Streptococcus thermophilus LMD-9

47.791

100

0.492
  mecA Streptococcus thermophilus LMG 18311

47.39

100

0.488

Multiple sequence alignment