Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   DQL23_RS02825 Genome accession   NZ_LS483341
Coordinates   603913..605760 (+) Length   615 a.a.
NCBI ID   WP_060552934.1    Uniprot ID   A0AB35FS50
Organism   Streptococcus gordonii strain NCTC7865     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 598913..610760
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL23_RS02810 (NCTC7865_00560) fmt 600917..601852 (+) 936 WP_060552936.1 methionyl-tRNA formyltransferase -
  DQL23_RS02815 (NCTC7865_00561) rsmB 601842..603155 (+) 1314 WP_060552935.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  DQL23_RS02820 (NCTC7865_00562) - 603176..603916 (+) 741 WP_060553304.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DQL23_RS02825 (NCTC7865_00563) stkP 603913..605760 (+) 1848 WP_060552934.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DQL23_RS02830 (NCTC7865_00564) liaF 605936..606634 (+) 699 WP_060553303.1 cell wall-active antibiotics response protein LiaF -
  DQL23_RS02835 (NCTC7865_00565) - 606631..607632 (+) 1002 WP_060552933.1 sensor histidine kinase -
  DQL23_RS02840 (NCTC7865_00566) - 607634..608266 (+) 633 WP_060552932.1 response regulator transcription factor -
  DQL23_RS02845 (NCTC7865_00567) - 608354..609757 (+) 1404 WP_060552931.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQL23_RS02850 (NCTC7865_00568) - 609754..610140 (+) 387 WP_060552930.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 615 a.a.        Molecular weight: 66891.01 Da        Isoelectric Point: 6.6769

>NTDB_id=1137455 DQL23_RS02825 WP_060552934.1 603913..605760(+) (stkP) [Streptococcus gordonii strain NCTC7865]
MIQIGKIFAGRYKIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRVTDIG
EEDGQQYLAMEYVAGLDLKRYIKEHSPLSNEEAVRIMGQILLAMRLAHARGIVHRDLKPQNVLLTPDGNAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIIAENANVP
QSLENVIIKATAKKLTDRYQSVSDMYVDLSSCLSPERRNEKKLMFDDAVKADTKTLPKIPQVTPPVASRVKNDPATDVEL
QAPQVAPPTKPKKKRHLRARYKVLLAAVFLVIAAFLALLYLTPSNKQVPDVTGKTVAEAREAIEKVNLKVGEEIEENSDE
VASGMIIRTDPVAGTQRKEGSTVNLVVSKGAKTLIMEDYTGQTTAQAVERLTDVLKVPKNNIKVEEVETNDVEEGTIFEQ
TPAAGATYDLTSNTKIVLKVAKAVSTIEMPNFGSLQYTYANARNYLISLGIPSSNIERVVDRSVVSSQSDLVTSQSPATG
PVNPKKVKVTLYVTEATTPSSSSSSSSNSSSSSKNTSSSSSSEDETSASSSTHGD

Nucleotide


Download         Length: 1848 bp        

>NTDB_id=1137455 DQL23_RS02825 WP_060552934.1 603913..605760(+) (stkP) [Streptococcus gordonii strain NCTC7865]
ATGATTCAAATCGGCAAAATTTTTGCCGGGCGATATAAAATCATCAAACAAATTGGCCGAGGCGGGATGGCAGATGTCTA
TCTTGCCAAGGATTTGATTTTAGATGGTGAAGAAGTGGCGGTTAAGGTTCTTAGAACCAATTACCAGACGGATCCTATCG
CTGTTGCACGTTTCCAACGAGAAGCGCGTGCCATGGCGGATTTGGACCATCCACATATCGTTCGTGTCACCGATATTGGT
GAAGAAGACGGCCAGCAATATTTGGCTATGGAATATGTAGCTGGCTTGGATCTCAAACGTTATATCAAGGAACACTCTCC
TTTGTCGAACGAAGAGGCCGTTCGAATTATGGGGCAAATTCTTTTAGCCATGCGTTTGGCACATGCTCGTGGGATTGTTC
ACCGAGATTTGAAACCGCAAAACGTTCTCCTGACTCCAGATGGAAATGCTAAGGTAACGGACTTTGGGATTGCGGTTGCC
TTTGCAGAAACAAGTTTGACCCAGACAAATTCAATGCTGGGCAGTGTTCATTACCTGTCTCCTGAGCAGGCGCGTGGTTC
GAAAGCAACTTTCCAAAGCGATATTTATGCGATGGGGATCATCTTTTATGAGATGCTGACTGGTCATATTCCTTATGATG
GGGATAGTGCAGTGACGATTGCTCTACAACATTTCCAAAAACCATTGCCGTCTATTATTGCTGAAAATGCCAATGTTCCG
CAGTCTCTGGAAAATGTTATTATTAAGGCTACCGCTAAAAAGCTGACAGACCGGTATCAAAGTGTTTCGGATATGTATGT
AGATCTGTCTAGTTGCCTGTCACCTGAACGACGGAATGAAAAGAAACTGATGTTTGATGACGCGGTAAAAGCGGATACTA
AGACACTTCCAAAGATTCCGCAAGTTACACCTCCTGTAGCTTCTAGAGTAAAAAATGATCCAGCTACAGATGTTGAACTG
CAAGCCCCTCAAGTTGCACCACCAACAAAACCTAAGAAAAAGCGTCATTTGAGAGCGAGATACAAGGTTTTGTTAGCTGC
AGTATTTCTGGTCATTGCTGCTTTTCTAGCATTGCTCTATCTAACACCATCTAATAAGCAGGTTCCAGATGTTACTGGCA
AGACCGTTGCTGAAGCTAGAGAAGCGATTGAAAAAGTCAATTTAAAAGTTGGTGAAGAGATAGAAGAGAATAGTGATGAA
GTAGCTTCAGGGATGATTATTCGCACAGATCCAGTGGCAGGAACTCAGAGAAAAGAAGGCAGTACAGTTAACTTAGTTGT
TTCTAAGGGAGCTAAAACGCTAATTATGGAAGACTATACTGGCCAAACGACTGCCCAAGCTGTTGAGAGACTCACGGATG
TTCTAAAAGTTCCAAAAAACAATATCAAAGTTGAAGAAGTTGAAACAAACGATGTAGAAGAAGGAACAATTTTTGAACAG
ACACCAGCTGCGGGAGCTACCTATGATCTCACTTCAAATACGAAGATTGTCTTAAAGGTAGCCAAAGCAGTATCAACGAT
TGAAATGCCAAACTTTGGTAGCCTTCAATATACTTATGCAAATGCTCGGAATTATCTGATTTCTCTAGGAATTCCATCTA
GTAACATTGAAAGAGTCGTGGATCGTTCGGTTGTGTCGAGTCAATCTGATTTGGTGACATCACAATCTCCAGCAACTGGA
CCAGTTAATCCTAAGAAGGTAAAAGTGACTTTGTATGTCACGGAAGCAACTACTCCAAGTTCAAGTTCTAGCTCGAGCTC
GAATTCTTCTTCTAGCAGTAAGAATACGTCATCGTCAAGTTCTTCAGAAGACGAAACGTCAGCATCAAGTTCGACACATG
GTGATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(435-502)

PASTA domain (PASTA)

(367-429)

PASTA domain (PASTA)

(508-574)

Protein kinase domain (Pkinase)

(12-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

70.577

84.553

0.597
  stkP Streptococcus pneumoniae D39

70.385

84.553

0.595
  stkP Streptococcus pneumoniae R6

70.385

84.553

0.595
  stkP Streptococcus pneumoniae Rx1

70.192

84.553

0.593
  pknB Streptococcus mutans UA159

58.217

93.008

0.541
  stkP/pknB Streptococcus salivarius strain HSISS4

57.664

89.106

0.514

Multiple sequence alignment