Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   DQL04_RS09285 Genome accession   NZ_LS483340
Coordinates   1825363..1826586 (+) Length   407 a.a.
NCBI ID   WP_047236072.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12062     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1820363..1831586
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL04_RS09270 - 1823164..1824256 (-) 1093 Protein_1721 IS30 family transposase -
  DQL04_RS09280 (NCTC12062_01840) rlmH 1824672..1825151 (-) 480 WP_002981964.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  DQL04_RS09285 (NCTC12062_01841) htrA 1825363..1826586 (+) 1224 WP_047236072.1 S1C family serine protease Regulator
  DQL04_RS09290 (NCTC12062_01842) spo0J 1826675..1827451 (+) 777 WP_002981939.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 42786.42 Da        Isoelectric Point: 7.3923

>NTDB_id=1137446 DQL04_RS09285 WP_047236072.1 1825363..1826586(+) (htrA) [Streptococcus pyogenes strain NCTC12062]
MPSMKHILKSLSILLVGFLGGLIAIITFNNLYPHSPSKINSGKATTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSS
SLSNPYTKLFGEGRSKENKDAELSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
VVRISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKNENGETVSTNAIQTDAAINPGNS
GGPLINIEGQVIGINSSKISSTPTGSNGNSGAVEGIGFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQ
INIPTSVTGGIVVAEVKEGMPASGKLAQYDVITEIDGKIVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKADIKLTKTT
QDLTKTQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=1137446 DQL04_RS09285 WP_047236072.1 1825363..1826586(+) (htrA) [Streptococcus pyogenes strain NCTC12062]
ATGCCAAGTATGAAACATATCTTAAAATCCTTAAGTATTTTACTAGTTGGATTTTTAGGAGGATTAATAGCAATTATTAC
ATTTAATAATCTCTACCCACATTCTCCTTCAAAAATAAATTCAGGTAAGGCAACAACTAGTAATATGGTTTTTAACAACA
CAACCAATACTACTAAAGCTGTCAAAGCTGTTCAAAATGCAGTTGTATCAGTTATTAATTATCAAGATAACCCTTCTTCA
TCCCTTTCTAACCCTTATACAAAACTCTTTGGAGAAGGGCGTTCAAAAGAGAATAAGGATGCTGAATTATCTATTTTTAG
TGAAGGATCTGGGGTCATTTATCGAAAAGATGGCAACTCCGCTTACGTTGTTACTAATAACCATGTTATCGACGGAGCTA
AACGGATTGAAATTCTTATGGCAGACGGATCTAAAGTTGTTGGTGAATTAGTTGGAGCTGATACTTATTCGGATTTAGCT
GTTGTTAGGATCTCTTCAGATAAGATAAAAACAGTAGCTGAATTTGCAGATTCTACAAAACTAAATGTTGGAGAAGTTGC
TATTGCTATCGGCAGCCCACTAGGAACACAATACGCTAATTCTGTTACTCAAGGAATCGTCTCTAGTTTAAGTCGTACTG
TAACTTTAAAAAACGAGAATGGTGAGACTGTCTCAACAAATGCTATTCAGACAGATGCTGCTATTAACCCTGGAAACTCT
GGTGGACCACTAATTAATATTGAGGGGCAAGTAATCGGAATTAATTCAAGTAAAATTTCTTCTACCCCAACTGGTAGCAA
CGGTAATAGTGGTGCTGTTGAAGGAATTGGTTTTGCTATCCCATCTACTGATGTTATTAAAATTATTAAACAACTAGAAA
CTAATGGTGAAGTTATCAGACCTGCTCTTGGAATATCCATGGTCAATTTAAATGACTTATCCACAAATGCTCTTAGCCAA
ATTAATATTCCAACTAGTGTAACTGGTGGTATTGTAGTAGCAGAAGTTAAGGAAGGAATGCCGGCATCTGGCAAACTTGC
TCAGTACGATGTGATTACAGAAATTGATGGCAAAATAGTTAATTCAATTAGTGATTTACAAAGTAGTCTATACGGACACG
ATATTAATGATACTATTAAAGTAACTTTTTATAGAGGAACTACAAAGAAAAAAGCAGATATCAAATTAACAAAAACTACT
CAAGATTTGACTAAAACGCAGTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(301-396)

Trypsin-like peptidase domain (Trypsin_2)

(109-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.634

99.263

0.612
  htrA Streptococcus gordonii str. Challis substr. CH1

55.721

98.771

0.55
  htrA Streptococcus mitis NCTC 12261

52.58

100

0.526
  htrA Streptococcus pneumoniae Rx1

52.334

100

0.523
  htrA Streptococcus pneumoniae D39

52.334

100

0.523
  htrA Streptococcus pneumoniae R6

52.334

100

0.523
  htrA Streptococcus pneumoniae TIGR4

52.334

100

0.523

Multiple sequence alignment