Detailed information NTG1137428

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQL04_RS04620
• Genome accession: NZ_LS483340
• Coordinates: 894312..895148 (-)
• Length: 278 a.a.
• NCBI ID: WP_047235811.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12062
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 889312..900148

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL04_RS04595 (NCTC12062_00913)	-	889532..890524 (-)	993	WP_047235809.1	D-lactate dehydrogenase	-
DQL04_RS04600 (NCTC12062_00914)	-	890539..891105 (-)	567	Protein_827	PTS sugar transporter subunit IIC	-
DQL04_RS09335	-	891145..892002 (+)	858	Protein_828	LysR family transcriptional regulator	-
DQL04_RS04615 (NCTC12062_00916)	topA	892077..894206 (-)	2130	WP_047235810.1	type I DNA topoisomerase	-
DQL04_RS04620 (NCTC12062_00917)	dprA	894312..895148 (-)	837	WP_047235811.1	DNA-processing protein DprA	Machinery gene
DQL04_RS04625 (NCTC12062_00918)	-	895213..896004 (-)	792	WP_002995007.1	ribonuclease HII	-
DQL04_RS04630 (NCTC12062_00919)	ylqF	895994..896842 (-)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
DQL04_RS04635 (NCTC12062_00920)	-	897061..897501 (+)	441	WP_011017769.1	DUF1836 domain-containing protein	-
DQL04_RS04640 (NCTC12062_00921)	trhA	897498..898148 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQL04_RS04645 (NCTC12062_00922)	-	898265..899176 (+)	912	WP_047235812.1	diacylglycerol/lipid kinase family protein	-
DQL04_RS04650 (NCTC12062_00923)	-	899226..899600 (-)	375	WP_047235813.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30993.02 Da
• Isoelectric Point: 9.2511

>NTDB_id=1137428 DQL04_RS04620 WP_047235811.1 894312..895148(-) (dprA) [Streptococcus pyogenes strain NCTC12062]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIISGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1137428 DQL04_RS04620 WP_047235811.1 894312..895148(-) (dprA) [Streptococcus pyogenes strain NCTC12062]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTATTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGCCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae D39	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae R6	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	59.712	100	0.597
dprA/cilB/dalA	Streptococcus mitis SK321	59.712	100	0.597
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.353	100	0.594
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	100	0.568