Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   DQL34_RS07930 Genome accession   NZ_LS483339
Coordinates   1494405..1496276 (-) Length   623 a.a.
NCBI ID   WP_084826071.1    Uniprot ID   A0A0E2Q2K5
Organism   Streptococcus thermophilus strain NCTC12958     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1489405..1501276
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL34_RS07895 (NCTC12958_01649) rimM 1489820..1490338 (-) 519 WP_084828975.1 ribosome maturation factor RimM -
  DQL34_RS07910 (NCTC12958_01652) - 1491008..1491652 (-) 645 WP_002951384.1 response regulator transcription factor -
  DQL34_RS07915 (NCTC12958_01653) - 1491642..1492652 (-) 1011 WP_100262586.1 sensor histidine kinase -
  DQL34_RS07920 (NCTC12958_01654) liaF 1492649..1493347 (-) 699 WP_014621793.1 cell wall-active antibiotics response protein LiaF -
  DQL34_RS12140 - 1493602..1493769 (-) 168 WP_014727613.1 potassium channel family protein -
  DQL34_RS07930 (NCTC12958_01655) stkP/pknB 1494405..1496276 (-) 1872 WP_084826071.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DQL34_RS07935 (NCTC12958_01656) - 1496276..1497013 (-) 738 WP_014727615.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DQL34_RS07940 (NCTC12958_01657) rsmB 1497057..1498379 (-) 1323 WP_111679780.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  DQL34_RS07945 (NCTC12958_01658) fmt 1498369..1499304 (-) 936 WP_084828976.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 623 a.a.        Molecular weight: 67905.81 Da        Isoelectric Point: 6.9480

>NTDB_id=1137371 DQL34_RS07930 WP_084826071.1 1494405..1496276(-) (stkP/pknB) [Streptococcus thermophilus strain NCTC12958]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNESVAIKVLRTNYQTDQVAVARFQREARAMTELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKFIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGRAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPFDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLATSLHPSHSRDSKVVFDDMTDTKTLPKVDSVPSVGPEKKISPKPSEPTPAP
SKQPREKASLSKKKKNLFLTLLKVLLGFVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKLESAGFKVGDVKEVEND
SVNKGKVIKTDPTAGTMRKEGASIDVYVSSGSKGFTLKNYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDNAKEGEILS
QSPEKNKSFNPKDSKAKIKFRVATPKTITMPDVTGLTVSTAVQTLNSKDISSSSIEYHDYNTGVKLDKSKVPSNTEVLYQ
DPQVGTAVDGTVILYVSVVTKSSSIQQSSSASTTQSPSSTSSSSESSTASSTETATEATHTEQ

Nucleotide


Download         Length: 1872 bp        

>NTDB_id=1137371 DQL34_RS07930 WP_084826071.1 1494405..1496276(-) (stkP/pknB) [Streptococcus thermophilus strain NCTC12958]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAATCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAACGACCTGATTCTGGATAATGAAAGTGTAGCTATTAAGGTGCTACGTACCAATTATCAAACTGATCAGGTTG
CTGTGGCGCGTTTCCAGCGTGAAGCACGTGCCATGACTGAGCTTAGCCATCCGAATATCGTTGCGATTAGAGATATTGGT
GAAGAAGACGGTCAGCAGTTCTTGGTGATGGAGTATGTGGATGGTTCGGACTTGAAGAAATTCATTCAAGACCATGCACC
ATTGTCTAACCAAGATGTTGTGCGTATTATGGGGGAAGTCCTTTCCGCCATGACTCTTGCCCACCAAAAGGGTATTATTC
ACCGTGACCTTAAGCCACAGAACGTTCTATTAACTAAGGATGGTAGAGCTAAGGTTACAGACTTTGGTATCGCAGTAGCA
TTTGCTGAAACCAGCCTGACACAAACTAACTCAATGTTGGGGTCAGTCCATTATTTGTCACCAGAACAGGCACGTGGTTC
TAAAGCCACTATCCAAAGTGATATCTATGCTATGGGGATTATGCTCTTTGAAATGTTGACAGGGCATATCCCTTTTGATG
GCGATAGTGCAGTAACCATTGCACTTCAACATTTCCAAAAGCCCCTGCCATCGATTTTGGCTGAGAACCGTAACGTTCCT
CAAGCTTTAGAAAATGTTGTTATTAGAGCAACTGCTAAAAAGCTTGAAAATCGTTACAACAGCACTTTGGAAATGAGTCG
CGACCTAGCAACTAGTTTGCATCCTAGTCATAGTCGTGATTCTAAGGTAGTTTTTGATGACATGACGGATACTAAGACCC
TGCCAAAGGTCGATTCAGTTCCATCAGTAGGTCCTGAGAAAAAGATTTCTCCTAAACCATCAGAGCCTACACCGGCTCCA
AGCAAACAACCGAGGGAAAAAGCTTCTCTATCTAAAAAAAAGAAAAATCTCTTTTTAACTCTACTCAAGGTTTTACTAGG
CTTCGTCTTTATAGGAATTATCATTTTTGCCTATCTTGTTTTTACCAATCCTGACAATGTCCAAGTACCAAATGTTGTAG
GTCAAGAGTTGTCAACAGCTCAGACGAAACTTGAAAGTGCAGGCTTTAAGGTTGGCGATGTTAAAGAAGTCGAAAATGAT
TCAGTCAATAAGGGCAAAGTTATCAAGACCGACCCTACAGCTGGGACAATGCGTAAAGAGGGAGCAAGCATTGATGTCTA
TGTTTCTTCTGGTAGCAAAGGTTTCACTCTGAAAAATTACAAGGGGAAAAATTATAAGGATGCCATTGAGGATTTAACCT
CGAATTATGGGGTTTCCGAGGATCAGATCGATATTCAACATGTCGAAGACGATAATGCTAAAGAAGGCGAAATTCTATCT
CAAAGTCCGGAGAAAAACAAGTCCTTCAATCCTAAAGATAGTAAGGCAAAAATCAAGTTTCGTGTGGCAACTCCTAAGAC
TATAACTATGCCTGATGTGACTGGTTTAACTGTCTCGACAGCAGTCCAAACCTTGAATAGTAAAGACATTTCAAGTAGCA
GTATTGAGTATCATGACTATAATACTGGTGTTAAGTTGGATAAGAGTAAGGTACCTAGTAATACAGAGGTCCTTTATCAA
GATCCTCAAGTTGGTACTGCTGTTGATGGCACAGTGATTCTCTATGTTTCAGTCGTAACTAAGAGTTCAAGTATTCAACA
GTCAAGCTCAGCAAGTACGACACAATCGCCGTCATCTACAAGTTCTAGTTCTGAAAGTAGTACAGCTTCTAGTACCGAAA
CAGCTACAGAAGCTACTCACACAGAGCAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(508-577)

PASTA domain (PASTA)

(436-502)

PASTA domain (PASTA)

(367-429)

Protein kinase domain (Pkinase)

(12-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2Q2K5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

90.706

93.258

0.846
  pknB Streptococcus mutans UA159

64.89

87.319

0.567
  stkP Streptococcus pneumoniae TIGR4

58.3

79.294

0.462
  stkP Streptococcus pneumoniae D39

58.097

79.294

0.461
  stkP Streptococcus pneumoniae R6

58.097

79.294

0.461
  stkP Streptococcus pneumoniae Rx1

57.895

79.294

0.459

Multiple sequence alignment