Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DQL47_RS08945 Genome accession   NZ_LS483328
Coordinates   1859882..1860646 (-) Length   254 a.a.
NCBI ID   WP_111690413.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC12090     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1854882..1865646
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL47_RS08925 (NCTC12090_01806) - 1855214..1856440 (-) 1227 WP_111690411.1 cysteine desulfurase -
  DQL47_RS08930 (NCTC12090_01807) sufD 1856467..1857729 (-) 1263 WP_043041107.1 Fe-S cluster assembly protein SufD -
  DQL47_RS08935 (NCTC12090_01808) sufC 1857821..1858591 (-) 771 WP_111690412.1 Fe-S cluster assembly ATPase SufC -
  DQL47_RS08940 (NCTC12090_01809) - 1858718..1859875 (-) 1158 WP_043031439.1 glycosyltransferase family 4 protein -
  DQL47_RS08945 (NCTC12090_01810) mecA 1859882..1860646 (-) 765 WP_111690413.1 adaptor protein MecA Regulator
  DQL47_RS08950 (NCTC12090_01811) - 1860766..1861605 (-) 840 WP_042671303.1 undecaprenyl-diphosphate phosphatase -
  DQL47_RS08955 (NCTC12090_01812) - 1861921..1863489 (+) 1569 WP_111690414.1 ABC transporter substrate-binding protein/permease -
  DQL47_RS08960 (NCTC12090_01813) - 1863482..1864222 (+) 741 WP_012677376.1 amino acid ABC transporter ATP-binding protein -
  DQL47_RS08965 (NCTC12090_01814) - 1864545..1864661 (+) 117 WP_012677375.1 putative metal homeostasis protein -

Sequence

Protein


Download         Length: 254 a.a.        Molecular weight: 29291.12 Da        Isoelectric Point: 4.2265

>NTDB_id=1136767 DQL47_RS08945 WP_111690413.1 1859882..1860646(-) (mecA) [Streptococcus equi subsp. zooepidemicus strain NCTC12090]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDL
NKDLNFEDLADLGDISQMTPEDFFRSLEQSMREKGDVNAHEKLEKIEEIMEDVVDATLAEQADNKEAAELEEPTEPLDYV
HYVLDFASVRDAVCFAKVIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARLIEHASPGTKTRAYLQEHGCQLI
FDGAVEELQKIRLG

Nucleotide


Download         Length: 765 bp        

>NTDB_id=1136767 DQL47_RS08945 WP_111690413.1 1859882..1860646(-) (mecA) [Streptococcus equi subsp. zooepidemicus strain NCTC12090]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGGGGGATGGAGCT
CAAGGACTTCTTGATCCCTCAAGAAAAGACAGAGGAGTTCTTTTATGCTGTCATGGACGAGTTGGACCTTCCGGACAATT
TTAAGGACAGTGGTATGCTTAGCTTTCGAGTGACTCCAAGAAAGGATCGCTTAGATGTTTTTGTGACCAAGTCAGACCTC
AATAAGGACCTTAATTTTGAGGATTTGGCAGACCTAGGTGATATTTCTCAAATGACTCCAGAGGATTTTTTCAGGAGCTT
GGAGCAGTCTATGCGTGAAAAGGGTGATGTCAATGCCCATGAAAAGCTTGAAAAAATCGAGGAGATCATGGAGGACGTGG
TAGATGCTACCTTGGCTGAGCAAGCAGATAATAAGGAAGCTGCTGAGCTTGAAGAGCCGACAGAGCCACTTGATTACGTT
CACTATGTTCTTGATTTTGCTTCTGTGCGAGACGCTGTTTGCTTTGCTAAGGTGATTGATTTTCCGATCGAGGCTTCTGA
ATTGTATAAGGGTCCTCGTCATTATCACATGACGATTTTACTTGATGTGCAAAACAAGCCTGCCTACTTTGCCAATGTGA
TGTATGCCAGATTGATTGAGCATGCTAGTCCTGGTACAAAAACAAGAGCTTATTTGCAGGAGCATGGTTGTCAGCTCATT
TTTGATGGTGCTGTTGAGGAGCTGCAAAAAATCAGGTTGGGGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.745

98.819

0.63
  mecA Streptococcus thermophilus LMD-9

56.471

100

0.567
  mecA Streptococcus thermophilus LMG 18311

55.686

100

0.559
  mecA Streptococcus pneumoniae TIGR4

48.031

100

0.48
  mecA Streptococcus pneumoniae Rx1

47.638

100

0.476
  mecA Streptococcus pneumoniae D39

47.638

100

0.476
  mecA Streptococcus pneumoniae R6

47.638

100

0.476

Multiple sequence alignment