Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   DQL47_RS08155 Genome accession   NZ_LS483328
Coordinates   1702738..1704633 (-) Length   631 a.a.
NCBI ID   WP_043052314.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC12090     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1697738..1709633
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL47_RS08130 (NCTC12090_01645) - 1698480..1698845 (-) 366 WP_042671180.1 S1 RNA-binding domain-containing protein -
  DQL47_RS08135 (NCTC12090_01646) - 1698845..1700245 (-) 1401 WP_111690351.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQL47_RS08140 (NCTC12090_01647) - 1700278..1700919 (-) 642 WP_111690352.1 response regulator transcription factor -
  DQL47_RS08145 (NCTC12090_01648) - 1700912..1701916 (-) 1005 WP_043052313.1 sensor histidine kinase -
  DQL47_RS08150 (NCTC12090_01649) liaF 1701913..1702605 (-) 693 WP_012679994.1 cell wall-active antibiotics response protein LiaF -
  DQL47_RS08155 (NCTC12090_01650) pknB 1702738..1704633 (-) 1896 WP_043052314.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DQL47_RS08160 (NCTC12090_01651) - 1704630..1705370 (-) 741 WP_043030079.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DQL47_RS08165 (NCTC12090_01652) rsmB 1705408..1706730 (-) 1323 WP_043030081.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  DQL47_RS08170 (NCTC12090_01653) fmt 1706720..1707655 (-) 936 WP_037579761.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 631 a.a.        Molecular weight: 68581.74 Da        Isoelectric Point: 6.6073

>NTDB_id=1136757 DQL47_RS08155 WP_043052314.1 1702738..1704633(-) (pknB) [Streptococcus equi subsp. zooepidemicus strain NCTC12090]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENPNVP
QALENVVIRATAKKLSDRYRSTFEMSRDLMTALSYNRSRERKVVFDDVESTKPLPKVTPTPVTAPKVSNASQASAAADAR
LEQTSQMDTLQKPQKKKKNGRFLGTLLKILFSFFVVGVALFAYLVLTKPTTVKVPDVTGSSLNAAKQVLEEAGLKVGKVH
QIESDTVSEDQVVKTNPQAGSAKRKGSSVDLYLSIGNKGFEMENYKGQDYQDVMTSLTETYGVPKSKIKIERIVTNEYPE
NTVISQSPSAGEKFNPAGKSKITLSVAVGDTVIMPMVTEYSYADAVNTLTALGIDAARIKAYVPSSSSPTGFVQVNSPSS
KAVVSGQTPYYGTQISLSEKGDISLYLYPEETRASSSSSSSDTSAPNPSAGDTTDSSSHTELGQNDAVTTP

Nucleotide


Download         Length: 1896 bp        

>NTDB_id=1136757 DQL47_RS08155 WP_043052314.1 1702738..1704633(-) (pknB) [Streptococcus equi subsp. zooepidemicus strain NCTC12090]
ATGATTCAGATTGGCAAGCTATTTGCTGGTCGTTATCGCATTCTAAAATCTATAGGCCGCGGTGGTATGGCGGATGTTTA
TTTAGCAAACGATTTGATTCTGGATAATGAGGACGTTGCCATTAAGGTCTTGCGGACCAATTATCAAACAGATCAGGTTG
CTGTTGCGCGTTTTCAAAGAGAAGCGCGAGCCATGGCTGAATTAAATCACCCCAATATTGTTGCCATTCGGGATATAGGC
GAGGAAGACGGACAGCAATTTTTAGTAATGGAATATGTTGATGGCTCTGATTTGAAAAAATACATTCAGGATCATGCGCC
ATTATCCAACAATGAGGTGGTGAGAATCATGGAAGAGGTTCTTTCTGCCATGACTCTGGCCCACCAAAAAGGAATTGTTC
ACAGGGATTTAAAGCCTCAAAACATTCTTTTGACCAAATCAGGTGTTGTTAAGGTTACAGATTTTGGGATTGCCGTTGCC
TTTGCAGAGACCAGTCTAACCCAGACAAATTCTATGCTAGGAAGTGTGCATTACCTCTCACCTGAGCAAGCGCGTGGTTC
TAAAGCGACGATTCAAAGTGATATTTACGCGATGGGAATTATGCTCTTTGAAATGCTAACAGGGCATATTCCTTATGATG
GCGATAGCGCTGTGACGATTGCTTTGCAGCATTTTCAAAAGCCGCTGCCCTCTATCATTGATGAAAATCCTAATGTGCCT
CAAGCCTTGGAGAACGTCGTTATTCGGGCTACTGCCAAAAAGCTAAGTGACCGTTATCGCTCGACCTTTGAGATGAGCAG
GGATTTGATGACAGCCCTTAGCTATAACCGCAGTCGTGAGCGTAAGGTTGTCTTTGATGATGTCGAAAGCACAAAGCCCT
TGCCAAAGGTAACACCGACTCCTGTAACAGCACCTAAGGTATCAAATGCTAGTCAGGCATCTGCGGCAGCTGATGCTAGA
CTTGAGCAGACTAGCCAGATGGATACTCTGCAAAAGCCTCAAAAAAAGAAAAAAAATGGGCGTTTTCTAGGAACACTCTT
AAAAATCTTGTTTTCCTTTTTTGTTGTTGGTGTGGCTCTTTTTGCTTATTTGGTCTTGACCAAGCCAACTACGGTTAAGG
TTCCTGATGTGACAGGCTCTAGTCTCAATGCTGCCAAGCAGGTCTTGGAGGAGGCGGGACTAAAGGTCGGTAAGGTCCAT
CAGATTGAAAGTGACACAGTTAGTGAGGATCAGGTGGTTAAGACAAATCCTCAAGCTGGCTCAGCTAAGCGAAAAGGCTC
CAGCGTTGACCTTTACCTTTCGATCGGAAATAAAGGCTTTGAGATGGAAAATTATAAGGGACAGGATTATCAAGATGTGA
TGACCAGTCTGACCGAGACCTATGGCGTACCAAAGTCAAAAATCAAGATTGAGCGTATCGTGACAAATGAATACCCTGAA
AACACCGTTATTAGCCAGTCTCCAAGCGCAGGAGAAAAATTTAACCCAGCTGGTAAATCTAAGATTACTCTCAGTGTAGC
AGTGGGTGATACGGTCATCATGCCAATGGTAACTGAGTACAGCTATGCAGATGCAGTCAATACACTAACAGCTTTAGGAA
TTGATGCCGCAAGAATCAAGGCCTATGTACCAAGCTCCAGCTCTCCGACAGGCTTTGTGCAGGTGAACTCCCCAAGCTCA
AAGGCGGTTGTCAGTGGGCAAACACCGTATTATGGTACCCAGATTAGCCTTTCTGAAAAGGGTGATATTAGCCTCTACCT
CTACCCTGAGGAGACACGTGCATCAAGCAGCTCATCGAGCTCTGATACCTCGGCTCCTAATCCATCAGCTGGAGATACAA
CAGACTCAAGCAGTCATACCGAATTAGGTCAAAATGACGCTGTTACAACACCGTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(512-588)

Protein kinase domain (Pkinase)

(12-232)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(441-506)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

65.546

94.295

0.618
  stkP/pknB Streptococcus salivarius strain HSISS4

62.245

93.185

0.58
  stkP Streptococcus pneumoniae TIGR4

57.558

81.775

0.471
  stkP Streptococcus pneumoniae D39

57.171

81.775

0.468
  stkP Streptococcus pneumoniae R6

57.171

81.775

0.468
  stkP Streptococcus pneumoniae Rx1

56.977

81.775

0.466

Multiple sequence alignment