Detailed information NTG1136742

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: DQL47_RS05010
• Genome accession: NZ_LS483328
• Coordinates: 1041709..1042383 (+)
• Length: 224 a.a.
• NCBI ID: WP_111678058.1
• Uniprot ID: A0AAX2LHX1
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC12090
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1036709..1047383

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL47_RS04995 (NCTC12090_01001)	pstB	1037037..1037795 (+)	759	WP_012678019.1	phosphate ABC transporter ATP-binding protein PstB	-
DQL47_RS05000 (NCTC12090_01002)	phoU	1037866..1038519 (+)	654	WP_012678018.1	phosphate signaling complex protein PhoU	-
DQL47_RS05005 (NCTC12090_01003)	-	1038753..1041290 (+)	2538	WP_111690093.1	M1 family metallopeptidase	-
DQL47_RS05010 (NCTC12090_01004)	ciaR	1041709..1042383 (+)	675	WP_111678058.1	response regulator transcription factor	Regulator
DQL47_RS05015 (NCTC12090_01005)	ciaH	1042376..1043686 (+)	1311	WP_111690094.1	sensor histidine kinase	Regulator
DQL47_RS05020 (NCTC12090_01006)	-	1044070..1044504 (+)	435	WP_012678015.1	hypothetical protein	-
DQL47_RS10255 (NCTC12090_01007)	-	1044586..1044762 (+)	177	WP_014622814.1	hypothetical protein	-
DQL47_RS05025 (NCTC12090_01008)	-	1044778..1045185 (+)	408	WP_014622815.1	hypothetical protein	-
DQL47_RS05030 (NCTC12090_01009)	-	1045195..1045440 (+)	246	WP_111690095.1	hypothetical protein	-
DQL47_RS05035 (NCTC12090_01010)	-	1045611..1045994 (+)	384	WP_041790456.1	hypothetical protein	-
DQL47_RS05040 (NCTC12090_01011)	-	1045991..1046236 (+)	246	WP_111690096.1	hypothetical protein	-
DQL47_RS05045 (NCTC12090_01012)	-	1046252..1046674 (+)	423	WP_111690097.1	hypothetical protein	-
DQL47_RS05050 (NCTC12090_01013)	-	1046843..1047169 (+)	327	WP_111690561.1	hypothetical protein	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25555.55 Da
• Isoelectric Point: 4.5644

>NTDB_id=1136742 DQL47_RS05010 WP_111678058.1 1041709..1042383(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain NCTC12090]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTA
KESIDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQVIELLGKELDLLVY
ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGYILKANE

Nucleotide

• Length: 675 bp

>NTDB_id=1136742 DQL47_RS05010 WP_111678058.1 1041709..1042383(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain NCTC12090]
ATGATAAAACTATTATTAGTAGAAGACGATTTAAGCTTGTCAAATTCTATCTTTGATTTTTTAGATGACTTTGCTGATGT
GACGCAGGTTTTTGATGGTGACGAAGGACTCTATGAGGCAGAAAGCGGTATTTATGATTTGATTCTGTTAGATTTGATGC
TGCCTGAAAAGGATGGCTTTCAAGTGTTAAAAGCCTTACGTGAAAAAGACATCAAAATTCCCGTCTTGATCATGACTGCC
AAAGAAAGCATCGATGACAAGGGGCATGGCTTTGAGCTTGGTGCTGATGACTATTTAACTAAGCCCTTTTACCTAGAAGA
ATTAAAAATGCGGATTCAGGCCTTGCTTAAGCGCGTAGGAAAGTTTAATGATAAGAGCCTTAAATTTGGCAACCTGACTG
TAGATACTACTCGTAAAGAGGTACAGGTCAATGGGCAGGTCATAGAGCTATTAGGTAAGGAGCTTGATTTACTAGTCTAT
ATTCTTCAAAATCAAAATGTTATTTTGCCAAAGTCACAAATTTTTGATCGTATCTGGGGCTTTGATAGTGATACCACTAT
CTCTGTTGTAGAGGTCTATGTCTCTAAAATCCGTAAGAAGCTTAAGGGGACAGACTTTGTTAATCATCTTCAAACCTTGA
GAAGTGTAGGATATATCTTAAAAGCTAATGAATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (5-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	85.068	98.661	0.839
ciaR	Streptococcus pneumoniae Rx1	80.995	98.661	0.799
ciaR	Streptococcus pneumoniae D39	80.995	98.661	0.799
ciaR	Streptococcus pneumoniae R6	80.995	98.661	0.799
ciaR	Streptococcus pneumoniae TIGR4	80.995	98.661	0.799
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.865	100	0.397