Detailed information NTG1136572

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: DQL35_RS04880
• Genome accession: NZ_LS483325
• Coordinates: 1009621..1010295 (+)
• Length: 224 a.a.
• NCBI ID: WP_111678058.1
• Uniprot ID: A0AAX2LHX1
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC7022
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1004621..1015295

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL35_RS04865 (NCTC7022_00972)	pstB	1004945..1005703 (+)	759	WP_012678019.1	phosphate ABC transporter ATP-binding protein PstB	-
DQL35_RS04870 (NCTC7022_00973)	phoU	1005774..1006427 (+)	654	WP_012678018.1	phosphate signaling complex protein PhoU	-
DQL35_RS04875 (NCTC7022_00974)	-	1006657..1009194 (+)	2538	WP_111678057.1	M1 family metallopeptidase	-
DQL35_RS04880 (NCTC7022_00975)	ciaR	1009621..1010295 (+)	675	WP_111678058.1	response regulator transcription factor	Regulator
DQL35_RS04885 (NCTC7022_00976)	ciaH	1010288..1011598 (+)	1311	WP_111678059.1	sensor histidine kinase	Regulator
DQL35_RS04890 (NCTC7022_00977)	-	1011983..1012411 (+)	429	WP_111678060.1	hypothetical protein	-
DQL35_RS04900 (NCTC7022_00978)	-	1012638..1013033 (+)	396	WP_111678061.1	DUF1433 domain-containing protein	-
DQL35_RS04905 (NCTC7022_00979)	-	1013033..1013278 (+)	246	WP_111678062.1	hypothetical protein	-
DQL35_RS04910 (NCTC7022_00980)	-	1013297..1013695 (+)	399	WP_231871354.1	hypothetical protein	-
DQL35_RS04915 (NCTC7022_00981)	-	1013698..1014891 (+)	1194	WP_231871355.1	hypothetical protein	-
DQL35_RS04920 (NCTC7022_00982)	-	1014888..1015280 (+)	393	WP_111678065.1	hypothetical protein	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25555.55 Da
• Isoelectric Point: 4.5644

>NTDB_id=1136572 DQL35_RS04880 WP_111678058.1 1009621..1010295(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain NCTC7022]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTA
KESIDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQVIELLGKELDLLVY
ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGYILKANE

Nucleotide

• Length: 675 bp

>NTDB_id=1136572 DQL35_RS04880 WP_111678058.1 1009621..1010295(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain NCTC7022]
ATGATAAAACTATTATTAGTAGAAGACGATTTAAGCTTATCAAATTCCATCTTTGATTTTTTAGATGACTTTGCTGATGT
AACCCAGGTTTTTGATGGCGACGAAGGACTCTATGAGGCAGAAAGCGGCATTTATGATTTGATTCTGTTAGATTTGATGC
TGCCTGAAAAGGATGGCTTTCAAGTGCTAAAGGCCTTACGTGAAAAAGACATCAAAATTCCCGTCTTGATCATGACTGCC
AAAGAAAGCATTGATGACAAGGGACATGGCTTTGAGCTTGGTGCTGATGACTATTTAACCAAGCCCTTTTACCTAGAGGA
ATTAAAAATGCGGATTCAGGCCTTGCTTAAGCGCGTAGGAAAGTTTAATGATAAGAGCCTTAAATTTGGTAACCTGACTG
TAGATACTACCCGTAAAGAGGTACAGGTCAATGGGCAGGTCATAGAGCTATTAGGTAAGGAGCTTGATTTACTAGTCTAT
ATTCTTCAAAACCAAAATGTTATTTTGCCAAAGTCACAAATTTTTGATCGTATCTGGGGCTTTGATAGTGATACCACTAT
CTCTGTTGTAGAGGTCTATGTCTCTAAAATCCGTAAGAAGCTCAAGGGGACAGACTTTGTTAATCATCTTCAAACCTTGA
GAAGTGTAGGATATATCTTAAAAGCTAATGAATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (5-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	85.068	98.661	0.839
ciaR	Streptococcus pneumoniae Rx1	80.995	98.661	0.799
ciaR	Streptococcus pneumoniae D39	80.995	98.661	0.799
ciaR	Streptococcus pneumoniae R6	80.995	98.661	0.799
ciaR	Streptococcus pneumoniae TIGR4	80.995	98.661	0.799
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.865	100	0.397