Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   DQL35_RS04885 Genome accession   NZ_LS483325
Coordinates   1010288..1011598 (+) Length   436 a.a.
NCBI ID   WP_111678059.1    Uniprot ID   A0AAX2LI37
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC7022     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1005288..1016598
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL35_RS04870 (NCTC7022_00973) phoU 1005774..1006427 (+) 654 WP_012678018.1 phosphate signaling complex protein PhoU -
  DQL35_RS04875 (NCTC7022_00974) - 1006657..1009194 (+) 2538 WP_111678057.1 M1 family metallopeptidase -
  DQL35_RS04880 (NCTC7022_00975) ciaR 1009621..1010295 (+) 675 WP_111678058.1 response regulator transcription factor Regulator
  DQL35_RS04885 (NCTC7022_00976) ciaH 1010288..1011598 (+) 1311 WP_111678059.1 sensor histidine kinase Regulator
  DQL35_RS04890 (NCTC7022_00977) - 1011983..1012411 (+) 429 WP_111678060.1 hypothetical protein -
  DQL35_RS04900 (NCTC7022_00978) - 1012638..1013033 (+) 396 WP_111678061.1 DUF1433 domain-containing protein -
  DQL35_RS04905 (NCTC7022_00979) - 1013033..1013278 (+) 246 WP_111678062.1 hypothetical protein -
  DQL35_RS04910 (NCTC7022_00980) - 1013297..1013695 (+) 399 WP_231871354.1 hypothetical protein -
  DQL35_RS04915 (NCTC7022_00981) - 1013698..1014891 (+) 1194 WP_231871355.1 hypothetical protein -
  DQL35_RS04920 (NCTC7022_00982) - 1014888..1015280 (+) 393 WP_111678065.1 hypothetical protein -
  DQL35_RS04925 (NCTC7022_00983) - 1015296..1015580 (+) 285 WP_012677440.1 hypothetical protein -
  DQL35_RS04930 (NCTC7022_00984) rpsT 1015793..1016026 (-) 234 WP_037578328.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49660.31 Da        Isoelectric Point: 9.5548

>NTDB_id=1136573 DQL35_RS04885 WP_111678059.1 1010288..1011598(+) (ciaH) [Streptococcus equi subsp. zooepidemicus strain NCTC7022]
MNKLKKELLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYSTVDSSLISVGQNASNYANRTMARISSFYFDAENNLI
QALPELEASKSLGSSTTNMDIILFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHIASSLDEVRNMRILTTNLLNLARRDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISAN
QINRPLKTDKALLKQLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVDKARTRQKG
GFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=1136573 DQL35_RS04885 WP_111678059.1 1010288..1011598(+) (ciaH) [Streptococcus equi subsp. zooepidemicus strain NCTC7022]
ATGAATAAACTAAAAAAAGAATTATTGTCCGATAATTATACACATTTTTTTCATTTCTTTGCTATTTTTACAGGCATTTT
TGTTGTCATGACCATCATTATTTTGCAAATCATGAGGTTTAGTGTCTATTCCACAGTAGACAGCAGTCTCATTTCGGTTG
GTCAAAATGCCAGCAACTATGCCAATAGGACCATGGCGAGAATATCTTCCTTTTATTTTGATGCAGAAAATAACCTTATT
CAGGCTCTTCCTGAATTGGAAGCGTCAAAATCACTTGGCTCCTCCACCACTAATATGGATATTATTTTATTTAGTGCCAA
TGGGACGATATTGAATTCCTTTGATGCCTTCTCCAATTACCAAAGCTTTCGTTTAGACAAAAGTCAGCTTAATAACATTG
TCACAACACAGCTGATGAATTTTTATGGGCAAAAGGAGAAATACCATACCCTAACCGTTAAGGTCCACATCAAAAACTAT
CCGGCAGTGGCTTATATGATGGCAGTGGTTAATGTTCAGCAACTGGATACTGCCAATGAGCGCTATGAACAGATTATTAT
CATGGTTATGATTGTCTTTTGGTTAATTTCGATTTTAGCCAGCATTTATTTAGCGAAATGGAGCAGAAAGCCAATTATGG
AGAGCTATGCCAAGCAAAAAATGTTTGTAGAAAATGCCAGTCATGAGCTTAGGACTCCTTTGGCTGTGCTGCAAAATCGT
TTGGAATCACTGTTTAGAAAGCCTAACGAGACCATTTTAGAAAATAGTGAGCATATTGCTTCAAGCCTAGATGAGGTCCG
CAATATGAGAATATTAACCACTAATTTGTTGAATTTAGCTAGACGCGATGATGGGATCAAGCCGCAGCTAGTTGATGTTG
ATGCAGCCTTTTTTGATACTGTTTTTGAAAATTATCAATTAGTTGCAGAAGAGTCAGGCAAGCAGTTTATCTCAGCTAAT
CAGATCAATAGGCCCTTAAAGACAGATAAGGCCTTACTAAAGCAGCTGATGACCATTTTGTTTGATAATGCGATCAAATA
CACTGATCATAACGGTGTGGTTGAGGTCAAGGTTAGAACGACTGATAAGCATTTATTGATTTCTGTTATTGATAATGGTC
CAGGGATTAAGGACGATGATAAGAAAAAGATTTTTGATCGCTTTTACCGAGTAGATAAGGCAAGGACACGCCAAAAAGGA
GGCTTTGGACTCGGATTGGCCTTAGCGCAACAGATCGTCACCTCATTAAAAGGAACGATTACTGTCAGTGATAATAAGCC
TACCGGCGCTATTTTTGAGGTAAAATTATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.666

100

0.578
  ciaH Streptococcus pneumoniae Rx1

51.147

100

0.511
  ciaH Streptococcus pneumoniae D39

51.147

100

0.511
  ciaH Streptococcus pneumoniae R6

51.147

100

0.511
  ciaH Streptococcus pneumoniae TIGR4

51.147

100

0.511

Multiple sequence alignment