Detailed information NTG1136563

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: DQL35_RS02670
• Genome accession: NZ_LS483325
• Coordinates: 539411..541564 (+)
• Length: 717 a.a.
• NCBI ID: WP_111677831.1
• Uniprot ID: A0AAX2LHA3
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC7022
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 534411..546564

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL35_RS02645 (NCTC7022_00525)	metG	534617..536620 (+)	2004	WP_111677830.1	methionine--tRNA ligase	-
DQL35_RS02650 (NCTC7022_00526)	-	537178..538071 (+)	894	WP_024273139.1	helix-turn-helix domain-containing protein	-
DQL35_RS02660 (NCTC7022_00528)	-	538423..538563 (+)	141	WP_012515166.1	hypothetical protein	-
DQL35_RS10605 (NCTC7022_00529)	-	538676..538834 (+)	159	WP_021320463.1	hypothetical protein	-
DQL35_RS10610 (NCTC7022_00530)	-	538848..538994 (+)	147	WP_021320464.1	hypothetical protein	-
DQL35_RS02665 (NCTC7022_00531)	-	539017..539184 (+)	168	WP_012515168.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
DQL35_RS02670 (NCTC7022_00532)	comA	539411..541564 (+)	2154	WP_111677831.1	peptide cleavage/export ABC transporter ComA	Regulator
DQL35_RS10915 (NCTC7022_00533)	comB	541579..542469 (+)	891	WP_269458659.1	bacteriocin secretion accessory protein	Regulator
DQL35_RS10920 (NCTC7022_00534)	-	542527..542964 (+)	438	WP_269458660.1	HlyD family efflux transporter periplasmic adaptor subunit	-
DQL35_RS02680 (NCTC7022_00535)	-	543455..543691 (+)	237	WP_111677832.1	hypothetical protein	-
DQL35_RS02685 (NCTC7022_00536)	nrdF	544148..545161 (+)	1014	WP_111677833.1	class 1b ribonucleoside-diphosphate reductase subunit beta	-
DQL35_RS02690 (NCTC7022_00537)	nrdI	545163..545570 (+)	408	WP_037581296.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80467.39 Da
• Isoelectric Point: 9.0606

>NTDB_id=1136563 DQL35_RS02670 WP_111677831.1 539411..541564(+) (comA) [Streptococcus equi subsp. zooepidemicus strain NCTC7022]
MKFRRKHYRAQVDTRDCGVASLAMIYGYYGSYYSLATLREAAKTTQEGTTAFGLVKVSEALGFETRAIRADMSLFDVEGL
SYPFIAHVLKKGKFLHYYVVTGQDKKYIHIADPDPTVKLTCLSRQRFASEWTGVTIFIAPTPEYKPHKEKKNSLLDFVPL
LAKQKGLITNIVVATLLVTIINIIGSYYLQSIIDTYVPSVMKNTLGIISVGLVIVYALQQVISYAQEYLLLILGQRLSID
VILSYIKHIFNLPMSFFATRRTGEIVSRFNDANSIIDALASTILSIFLDVSVIVIISLVLFSQNVNLFVISLLALPIYAV
IIFAFMKPFERMNQETMEANSIMSSSIIEDINGIETIKSLTSEKIRYQKIDKEFVAYLKKSFNYSRAESQQRALKKVAQL
VLNVSILWIGANLVMDGKMSLGQLITYNSLLIYFTNPLENIINLQTKLQTAQVANNRLNEVYLVESEFSEKKNVQDLSLT
SGDIKFNDVSYRYGYGKDVLSEINLHIKRGSKVAFVGISGSGKTTLAKMIVSFFEPSKGEISLNNVNLNQIDKHALRQHI
NYLPQQPYVFNGTILENLLLGAREGTTQEDIMKAVELAEIKSDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDS
PVLILDEATSNLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEHVVVLDKGKIIEQGTHRDLVSQNGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=1136563 DQL35_RS02670 WP_111677831.1 539411..541564(+) (comA) [Streptococcus equi subsp. zooepidemicus strain NCTC7022]
ATGAAATTTAGAAGAAAACACTACCGTGCTCAGGTTGATACTCGCGATTGTGGCGTAGCTTCTCTGGCCATGATTTACGG
TTATTATGGATCGTATTATTCGCTAGCAACGTTACGTGAAGCTGCAAAGACAACGCAGGAAGGGACTACAGCTTTTGGTT
TAGTCAAAGTTTCTGAGGCGCTTGGGTTTGAAACGAGAGCTATTAGGGCTGACATGAGTTTATTTGATGTGGAAGGATTA
TCTTATCCTTTTATTGCCCATGTTCTAAAAAAAGGTAAGTTCCTTCATTATTATGTGGTAACAGGACAAGATAAAAAATA
TATTCATATTGCAGATCCAGATCCAACTGTAAAGTTGACTTGTCTTTCTCGTCAGCGATTTGCTTCAGAGTGGACAGGTG
TGACAATTTTTATCGCTCCTACTCCTGAATACAAACCTCACAAGGAAAAGAAAAATAGTCTGCTAGATTTTGTGCCTCTC
CTAGCAAAGCAAAAAGGATTGATTACTAATATCGTTGTGGCAACGCTTTTGGTAACGATTATCAATATTATTGGTTCGTA
TTATCTTCAATCAATCATTGATACCTATGTTCCTAGTGTGATGAAGAATACACTAGGTATTATTTCCGTAGGTTTGGTTA
TTGTCTATGCCCTTCAACAAGTGATCTCATATGCGCAAGAGTATTTATTGCTGATATTAGGGCAACGTTTATCTATTGAT
GTAATTCTTTCTTATATCAAACATATTTTCAACCTTCCTATGTCTTTTTTCGCGACGAGAAGGACCGGGGAAATTGTTTC
TCGTTTTAATGATGCTAATTCAATCATTGATGCTTTAGCAAGTACAATTTTATCTATTTTCCTTGATGTTTCTGTCATTG
TAATTATATCTCTTGTTCTTTTTTCGCAAAATGTAAATCTATTTGTTATCAGTTTGCTTGCTCTGCCTATCTATGCAGTG
ATTATCTTTGCCTTCATGAAGCCATTTGAACGGATGAATCAAGAGACAATGGAAGCAAATTCAATCATGTCATCTTCTAT
TATTGAAGATATAAACGGTATTGAGACTATTAAATCATTAACTAGCGAAAAGATAAGATACCAAAAAATAGATAAAGAAT
TTGTAGCTTATCTTAAGAAATCTTTCAACTATAGTAGGGCAGAAAGCCAACAACGAGCATTGAAAAAAGTAGCTCAGCTT
GTCCTAAACGTGAGCATACTCTGGATAGGAGCCAATCTGGTTATGGACGGAAAAATGAGTTTAGGTCAACTGATTACCTA
TAACTCTCTCCTAATCTATTTTACAAATCCTCTGGAGAATATTATCAATCTTCAAACGAAACTTCAAACCGCTCAAGTCG
CTAATAATCGATTGAATGAGGTATATCTAGTTGAATCCGAGTTCTCTGAAAAGAAGAATGTTCAAGACTTATCTTTGACC
TCTGGTGACATAAAATTCAATGATGTTAGCTATCGATATGGATATGGAAAAGATGTTTTATCAGAAATAAATTTGCATAT
TAAACGAGGAAGCAAGGTTGCTTTTGTTGGGATTTCAGGTTCTGGAAAAACGACTTTAGCTAAGATGATTGTCAGTTTCT
TTGAACCAAGCAAAGGCGAAATATCATTAAATAATGTGAATCTAAATCAAATTGACAAACATGCTCTTCGCCAGCACATT
AACTATCTTCCTCAACAACCTTACGTATTTAATGGGACAATCCTTGAGAATTTACTTCTTGGAGCACGTGAAGGGACGAC
TCAAGAAGACATTATGAAGGCAGTAGAATTGGCTGAAATCAAGTCTGATATTGAACGTATGCCTTTGAATTATCAAACAG
AGTTAACCTCAGATGGTGCAGGGATTTCTGGAGGTCAACGTCAACGTATTGCCTTAGCAAGGGCATTATTGACAGATTCT
CCTGTTTTGATATTAGACGAAGCTACAAGTAACTTGGATATTTTGACTGAGAAGCGAATTGTTGATAACCTGATGGCTTT
AGATAAAACCTTGATATTTATTGCTCACCGTTTAACTATTGCAGAGCGTACAGAGCATGTCGTCGTTTTGGATAAAGGAA
AGATCATAGAGCAAGGAACACACAGAGACCTTGTTTCTCAGAATGGCTTTTATGCTCACTTGGTCAATAGTTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-650)

• ABC transporter transmembrane region (ABC_membrane) (169-438)

• Peptidase C39 family (Peptidase_C39) (6-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	82.148	100	0.821
comA	Streptococcus mitis SK321	81.729	100	0.817
comA	Streptococcus pneumoniae Rx1	81.729	100	0.817
comA	Streptococcus pneumoniae D39	81.729	100	0.817
comA	Streptococcus pneumoniae R6	81.729	100	0.817
comA	Streptococcus pneumoniae TIGR4	81.45	100	0.815
comA	Streptococcus gordonii str. Challis substr. CH1	78.522	100	0.785
comA/nlmT	Streptococcus mutans UA159	62.762	100	0.628