Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   DQL15_RS06725 Genome accession   NZ_LS483323
Coordinates   1332502..1333212 (-) Length   236 a.a.
NCBI ID   WP_111689248.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8300     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1327502..1338212
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL15_RS06710 (NCTC8300_01331) rnc 1329220..1329912 (-) 693 WP_002990670.1 ribonuclease III -
  DQL15_RS06715 (NCTC8300_01332) vicX 1330344..1331153 (-) 810 WP_002985641.1 MBL fold metallo-hydrolase Regulator
  DQL15_RS06720 (NCTC8300_01333) vicK 1331157..1332509 (-) 1353 WP_002990673.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQL15_RS06725 (NCTC8300_01334) vicR 1332502..1333212 (-) 711 WP_111689248.1 response regulator YycF Regulator
  DQL15_RS06730 (NCTC8300_01335) - 1333374..1334408 (-) 1035 WP_002990676.1 DUF3114 domain-containing protein -
  DQL15_RS06735 (NCTC8300_01336) - 1334464..1335711 (-) 1248 WP_002990679.1 AMP-binding protein -
  DQL15_RS06740 (NCTC8300_01337) - 1335668..1336816 (-) 1149 WP_002990683.1 acetyl-CoA C-acyltransferase -
  DQL15_RS06745 - 1337211..1337360 (-) 150 WP_002990686.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27110.02 Da        Isoelectric Point: 4.8203

>NTDB_id=1136488 DQL15_RS06725 WP_111689248.1 1332502..1333212(-) (vicR) [Streptococcus pyogenes strain NCTC8300]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
LTYREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1136488 DQL15_RS06725 WP_111689248.1 1332502..1333212(-) (vicR) [Streptococcus pyogenes strain NCTC8300]
ATGAAAAAAATACTTATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAATTTGACAAAAGAAGGTTATGA
CATTGTTACAGCTTTTGATGGACGCGAAGCGGTAACAATTTTTGAAGAAGAAAAGCCAGATTTAATTATTCTTGATTTGA
TGCTCCCTGAGTTGGACGGTCTTGAAGTAGCCAAGGAAATTCGTAAAACCAGTCATGTCCCGATTATTATGTTGTCGGCT
AAAGATAGTGAGTTTGACAAGGTTATTGGACTTGAAATTGGGGCTGATGATTACGTGACCAAGCCCTTTTCTAATCGGGA
ATTGCTGGCACGTGTCAAGGCTCATCTGCGTCGTACCGAAACTATTGAAACGGCTGTTGCAGAAGAAAATGCTTCTTCAG
GTACACAGGAACTAACCATTGGTAATTTACAGATTTTACCAGATGCGTTTGTTGCTAAAAAACATGGTCAAGAGGTAGAG
TTGACCTATCGTGAATTTGAACTATTGCATCATCTAGCTAACCATATGGGTCAGGTGATGACACGAGAACACTTATTGGA
AATTGTTTGGGGATATGATTATTTTGGCGATGTGCGCACGGTTGATGTGACTGTTCGTCGTCTCCGTGAAAAAATTGAAG
ACACACCAAGTCGTCCTGAGTATATTTTAACAAGACGTGGTGTTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

89.831

100

0.898
  micA Streptococcus pneumoniae Cp1015

78.632

99.153

0.78
  covR Streptococcus salivarius strain HSISS4

44.828

98.305

0.441
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

36.91

98.729

0.364

Multiple sequence alignment