Detailed information NTG1136206

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: DQM44_RS05405
• Genome accession: NZ_LS483318
• Coordinates: 1035421..1036095 (-)
• Length: 224 a.a.
• NCBI ID: WP_111711635.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 1030421..1041095

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM44_RS05380 (NCTC5370_01114)	-	1030607..1031884 (-)	1278	WP_065354777.1	pyrimidine-nucleoside phosphorylase	-
DQM44_RS05385 (NCTC5370_01115)	-	1031871..1032470 (-)	600	WP_015057597.1	class I SAM-dependent methyltransferase	-
DQM44_RS05390 (NCTC5370_01116)	coaA	1032738..1033658 (+)	921	WP_111711634.1	type I pantothenate kinase	-
DQM44_RS05395 (NCTC5370_01117)	rpsT	1033712..1033960 (+)	249	WP_009881183.1	30S ribosomal protein S20	-
DQM44_RS05400 (NCTC5370_01118)	ciaH	1034118..1035428 (-)	1311	WP_014612303.1	HAMP domain-containing sensor histidine kinase	Regulator
DQM44_RS05405 (NCTC5370_01119)	ciaR	1035421..1036095 (-)	675	WP_111711635.1	response regulator transcription factor	Regulator
DQM44_RS05410 (NCTC5370_01120)	-	1036299..1038836 (-)	2538	WP_111711636.1	M1 family metallopeptidase	-
DQM44_RS05420 (NCTC5370_01121)	phoU	1039036..1039689 (-)	654	WP_003057760.1	phosphate signaling complex protein PhoU	-
DQM44_RS05425 (NCTC5370_01122)	pstB	1039767..1040525 (-)	759	WP_003057749.1	phosphate ABC transporter ATP-binding protein PstB	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25594.58 Da
• Isoelectric Point: 4.4128

>NTDB_id=1136206 DQM44_RS05405 WP_111711635.1 1035421..1036095(-) (ciaR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEGESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KESLDDKGQGFELGADDYLTKPFYLEELKMRIQALLKRTGKFTDKNLAFGNVVVDLGQKEVQVDGRPIELLGKEFDLLVY
LLQNQNVILLKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDFVDKLQTLRSVGYILKSHE

Nucleotide

• Length: 675 bp

>NTDB_id=1136206 DQM44_RS05405 WP_111711635.1 1035421..1036095(-) (ciaR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370]
ATGATCAAACTATTATTAGTAGAAGATGACTTAAGTTTATCCAATTCCATTTTCGATTTTTTGGATGATTTTGCTGATGT
CACACAAGTTTTTGATGGCGATGAAGGCTTATATGAAGGCGAAAGTGGCATTTACGATTTGATTTTACTTGACCTTATGT
TGCCAGAAAAAAATGGCTTCCAAGTCTTGAAAGAATTGCGAGAAAAAGATATTAAAATTCCTGTGTTGATTATGACAGCC
AAAGAAAGCCTAGATGATAAGGGACAGGGCTTTGAATTAGGAGCAGATGATTACCTCACTAAGCCTTTTTACCTGGAGGA
ACTCAAGATGCGAATTCAAGCCCTGTTAAAACGTACAGGGAAATTCACGGATAAAAATCTAGCCTTTGGGAATGTCGTAG
TGGATTTAGGACAAAAAGAAGTTCAAGTGGATGGCCGGCCGATAGAACTATTAGGTAAAGAGTTTGATTTGTTGGTCTAC
CTGTTACAAAATCAGAATGTTATTTTACTTAAAACACAAATTTTTGATCGCTTATGGGGTTTTGATAGCGATACGACCAT
TTCAGTAGTTGAAGTTTACGTTTCTAAAATTAGAAAAAAACTGAAAGGTACAGATTTTGTGGACAAACTGCAGACATTGA
GAAGCGTGGGGTATATTCTAAAAAGCCATGAATAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

• Response regulator receiver domain (Response_reg) (5-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	83.258	98.661	0.821
ciaR	Streptococcus pneumoniae D39	83.258	98.661	0.821
ciaR	Streptococcus pneumoniae R6	83.258	98.661	0.821
ciaR	Streptococcus pneumoniae TIGR4	83.258	98.661	0.821
ciaR	Streptococcus mutans UA159	82.805	98.661	0.817
covR	Lactococcus lactis subsp. lactis strain DGCC12653	37.885	100	0.384
vicR	Streptococcus mutans UA159	35.443	100	0.375