Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   DQL78_RS02185 Genome accession   NZ_LS483306
Coordinates   409104..410351 (-) Length   415 a.a.
NCBI ID   WP_016251474.1    Uniprot ID   -
Organism   Enterococcus cecorum strain NCTC12421     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 404104..415351
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL78_RS02165 (NCTC12421_00440) ytpR 404211..404822 (+) 612 WP_016251469.1 YtpR family tRNA-binding protein -
  DQL78_RS12320 (NCTC12421_00441) - 404896..405066 (-) 171 WP_016251470.1 hypothetical protein -
  DQL78_RS02170 (NCTC12421_00442) - 405069..406286 (-) 1218 WP_026209945.1 MFS transporter -
  DQL78_RS02180 (NCTC12421_00445) - 408207..408863 (+) 657 WP_016251473.1 Crp/Fnr family transcriptional regulator -
  DQL78_RS02185 (NCTC12421_00446) htrA 409104..410351 (-) 1248 WP_016251474.1 S1C family serine protease Regulator
  DQL78_RS02190 (NCTC12421_00447) rlmH 410808..411287 (+) 480 WP_016251475.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  DQL78_RS02195 (NCTC12421_00448) - 411295..411993 (+) 699 WP_016251476.1 hypothetical protein -
  DQL78_RS02200 (NCTC12421_00449) - 412141..413319 (+) 1179 WP_016251477.1 MalY/PatB family protein -
  DQL78_RS02205 (NCTC12421_00450) - 413346..414446 (+) 1101 WP_016251478.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
  DQL78_RS02210 (NCTC12421_00451) - 414449..415198 (+) 750 WP_016251479.1 NADPH-dependent oxidoreductase -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 43114.09 Da        Isoelectric Point: 5.4559

>NTDB_id=1135710 DQL78_RS02185 WP_016251474.1 409104..410351(-) (htrA) [Enterococcus cecorum strain NCTC12421]
MSRRKNSNTIMKRFGIGICSGVIGGALAFGGLYAVTGMNHTTSSTGIQSAQTATKVKNVKYNVESDVTKAVSKVQGAVVS
IINLQNQNAQGTGSLEDFFGAQQGNSSSQNSGTLETASEGSGVIYKKEGKHAYIVTNNHVVEGQNALQVLLADGTKVDAE
LVGTDSYTDLAVIKIASDKVSTVATFGDSDSLKVGEPAIAIGSPLGTDYANSVTEGIISSLNRQVVSENDSGQEVNINAI
QTDAAINPGNSGGPLINIAGQVIGINSSKIATTSTSSSGVSVEGMGFAIPSNDVVNIINQLEQSGKVTRPALGVRTVDLN
ALSDQQKTNILKVPASLNEGVVLAQVNSATPAEKAGLKQYDVITEIDGEKVNDGTALRAALYKKQVGDSIKVTYYRGNDK
KTTTVHLTVDQSINE

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=1135710 DQL78_RS02185 WP_016251474.1 409104..410351(-) (htrA) [Enterococcus cecorum strain NCTC12421]
ATGAGTAGAAGAAAAAATTCAAATACAATTATGAAAAGATTTGGTATCGGCATTTGTAGCGGTGTAATTGGTGGTGCCCT
TGCTTTTGGCGGCTTGTATGCAGTCACTGGAATGAATCATACGACTAGCTCAACAGGTATTCAAAGTGCACAAACAGCAA
CTAAAGTTAAAAATGTGAAATATAATGTAGAAAGCGACGTAACAAAAGCGGTCTCTAAAGTACAAGGTGCAGTCGTTTCA
ATCATTAATTTACAAAATCAAAACGCACAAGGCACGGGCAGTTTAGAAGATTTCTTTGGTGCCCAACAAGGAAATAGTAG
CAGTCAAAATAGCGGTACTTTGGAAACAGCCAGTGAAGGTAGTGGTGTCATTTATAAAAAAGAAGGTAAACATGCTTATA
TCGTGACAAATAATCACGTGGTTGAAGGTCAAAATGCATTACAAGTCTTACTAGCAGACGGTACCAAAGTCGATGCTGAA
TTAGTTGGTACGGACAGCTATACTGACTTAGCGGTAATCAAGATTGCTAGCGATAAAGTTTCAACGGTTGCTACTTTTGG
AGATTCAGATAGTCTAAAAGTTGGTGAACCTGCCATCGCCATCGGATCACCATTAGGAACTGATTATGCCAACTCAGTGA
CTGAAGGAATTATTTCCTCTTTAAATCGTCAAGTCGTGAGTGAAAATGATTCCGGTCAAGAAGTCAATATCAATGCTATC
CAAACTGATGCAGCGATTAACCCTGGTAACTCTGGTGGTCCATTAATTAATATCGCCGGTCAAGTTATCGGAATTAACTC
AAGTAAAATTGCTACCACTTCAACCTCAAGCTCTGGTGTAAGTGTTGAAGGTATGGGCTTTGCAATTCCAAGTAATGATG
TCGTCAATATTATTAATCAACTAGAACAAAGTGGGAAAGTAACTCGTCCTGCTTTAGGGGTTAGAACGGTTGATTTGAAT
GCTTTATCTGATCAACAAAAAACAAACATCTTAAAAGTACCTGCCTCATTAAATGAAGGTGTCGTGCTTGCTCAAGTCAA
TAGCGCAACGCCTGCAGAAAAAGCTGGCTTGAAACAATATGATGTCATTACTGAAATTGATGGTGAAAAGGTCAATGATG
GCACTGCATTAAGAGCCGCGCTTTATAAAAAACAAGTCGGTGACAGCATTAAAGTGACTTACTATCGTGGCAATGACAAA
AAGACAACCACCGTACACCTTACCGTCGACCAATCAATTAATGAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(310-407)

Peptidase family M50 (Peptidase_M50)

(251-410)

Trypsin-like peptidase domain (Trypsin_2)

(120-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.461

85.783

0.484
  htrA Streptococcus gordonii str. Challis substr. CH1

48.649

98.072

0.477
  htrA Streptococcus pneumoniae R6

48.529

98.313

0.477
  htrA Streptococcus pneumoniae TIGR4

48.529

98.313

0.477
  htrA Streptococcus pneumoniae D39

48.529

98.313

0.477
  htrA Streptococcus pneumoniae Rx1

48.529

98.313

0.477
  htrA Streptococcus mitis NCTC 12261

50.131

91.807

0.46

Multiple sequence alignment