Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   MEPL_RS01505 Genome accession   NZ_CP006683
Coordinates   345696..347003 (-) Length   435 a.a.
NCBI ID   WP_048589650.1    Uniprot ID   -
Organism   Melissococcus plutonius S1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 340696..352003
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MEPL_RS01485 (MEPL_c002950) mreC 341287..342144 (+) 858 WP_013773244.1 rod shape-determining protein MreC -
  MEPL_RS01490 (MEPL_c002960) mreD 342147..342656 (+) 510 WP_048589648.1 rod shape-determining protein MreD -
  MEPL_RS01495 (MEPL_c002970) - 342960..344498 (+) 1539 WP_048589649.1 CHAP domain-containing protein -
  MEPL_RS01500 (MEPL_c002980) - 344747..345316 (+) 570 WP_013773247.1 TetR/AcrR family transcriptional regulator -
  MEPL_RS01505 (MEPL_c002990) htrA 345696..347003 (-) 1308 WP_048589650.1 S1C family serine protease Regulator
  MEPL_RS01510 (MEPL_c003000) rlmH 347345..347824 (+) 480 WP_048589651.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  MEPL_RS01515 (MEPL_c003010) - 348918..349358 (+) 441 WP_127468627.1 hypothetical protein -
  MEPL_RS09545 - 349595..349768 (+) 174 WP_013773252.1 hypothetical protein -

Sequence

Protein


Download         Length: 435 a.a.        Molecular weight: 45793.46 Da        Isoelectric Point: 6.7497

>NTDB_id=113385 MEPL_RS01505 WP_048589650.1 345696..347003(-) (htrA) [Melissococcus plutonius S1]
MERKNVTPISNKKNSFFKKFGIGLLGGVVGGVLIIGGTYAAVGMNVLPSPSATNTNNSLTPAKSTKVSNINYNVNSDVTK
AVNKTQDSVVSVINLQQKKSSSDLDGLDGLFGNDDNNNKKNKDNSSGGLEAASEGSGVIYKKDGNTAYVVTNNHVVDQSN
GLEVILHDGTKVKGKLVGKDAYTDLAVIKIAAQKVDQIATFGDSSKLKVGEPAIAIGSPLGSEYANSVTQGIISSVNRNI
TNANESGETVNINAIQTDAAINPGNSGGPLINIEGQVIGINSIKILQANSQVNVEGMGFAIPSNDVVSIINQLEAKGKVT
RPALGITMEDLSNISSQQQEEILKLPSSIKSGIVVLSVQAATPADKSGLKKYDVITKVDGENINTITDLQSALYKKNVGD
SMEVTYYRESKEHTASVDLTIDKSALKQPSIQENR

Nucleotide


Download         Length: 1308 bp        

>NTDB_id=113385 MEPL_RS01505 WP_048589650.1 345696..347003(-) (htrA) [Melissococcus plutonius S1]
ATGGAAAGAAAAAATGTAACACCTATTTCTAATAAAAAAAATTCATTTTTTAAAAAATTTGGCATTGGTTTACTCGGTGG
TGTAGTAGGCGGTGTTTTAATCATTGGTGGTACTTATGCTGCAGTTGGTATGAATGTTTTACCCTCTCCATCTGCCACAA
ATACAAATAATTCTTTAACGCCAGCTAAAAGCACTAAAGTAAGTAATATTAATTATAATGTAAATAGTGATGTAACAAAA
GCTGTTAATAAAACTCAAGATTCAGTCGTTTCTGTGATCAATCTACAACAAAAAAAATCTTCTTCTGATTTAGATGGCTT
AGATGGTCTCTTTGGAAATGATGATAATAACAATAAAAAAAATAAGGATAATAGTTCAGGTGGCTTAGAAGCTGCTAGTG
AAGGTAGTGGCGTTATTTATAAAAAAGATGGCAATACTGCCTATGTCGTAACCAATAATCATGTAGTTGATCAATCAAAC
GGATTGGAAGTTATTTTACATGATGGAACAAAAGTTAAAGGGAAATTAGTTGGAAAAGATGCTTATACCGATTTAGCAGT
TATTAAAATTGCTGCCCAAAAAGTAGATCAAATTGCTACATTCGGAGACTCTAGTAAACTAAAAGTTGGCGAACCCGCCA
TTGCAATTGGTTCTCCATTAGGTTCAGAGTATGCCAACTCGGTTACACAAGGAATTATTTCTTCAGTAAATCGTAATATT
ACAAATGCAAATGAATCGGGAGAAACTGTCAATATTAATGCAATACAGACAGATGCAGCAATTAATCCCGGAAATTCTGG
TGGTCCACTAATTAATATTGAAGGACAAGTTATTGGGATTAACTCCATTAAAATCCTTCAAGCTAATAGTCAAGTTAATG
TTGAAGGTATGGGATTCGCTATTCCTAGTAATGATGTTGTATCTATTATCAACCAACTAGAAGCCAAAGGAAAAGTAACA
CGCCCAGCATTAGGAATCACAATGGAAGACCTATCAAATATTTCTTCACAACAACAAGAAGAAATATTGAAATTACCTTC
TTCTATAAAATCTGGTATTGTTGTTCTTTCTGTTCAGGCAGCAACACCAGCCGATAAATCAGGTTTAAAAAAATATGATG
TCATTACAAAGGTTGATGGAGAAAATATCAATACAATCACAGATCTACAAAGTGCACTTTATAAAAAAAATGTTGGTGAC
TCAATGGAGGTAACCTATTATCGTGAATCAAAAGAGCATACTGCATCTGTTGATTTAACAATTGACAAATCAGCATTAAA
ACAACCTTCTATACAAGAAAATCGTTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(135-280)

Peptidase family M50 (Peptidase_M50)

(54-420)

PDZ domain (PDZ_2)

(322-419)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

53.253

95.402

0.508
  htrA Streptococcus gordonii str. Challis substr. CH1

52.174

95.172

0.497
  htrA Streptococcus mitis NCTC 12261

51.095

94.483

0.483
  htrA Streptococcus pneumoniae TIGR4

54.598

80

0.437
  htrA Streptococcus pneumoniae Rx1

54.598

80

0.437
  htrA Streptococcus pneumoniae D39

54.598

80

0.437
  htrA Streptococcus pneumoniae R6

54.598

80

0.437

Multiple sequence alignment