Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   H1W81_RS01280 Genome accession   NZ_LR824002
Coordinates   241431..242666 (-) Length   411 a.a.
NCBI ID   WP_011226713.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_67     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 236431..247666
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W81_RS01260 (STHERMO_0254) - 237461..237652 (-) 192 WP_002886272.1 DUF951 domain-containing protein -
  H1W81_RS01265 (STHERMO_0255) dnaN 237703..238839 (-) 1137 WP_002948931.1 DNA polymerase III subunit beta -
  H1W81_RS01270 (STHERMO_0256) dnaA 238994..240358 (-) 1365 WP_002948584.1 chromosomal replication initiator protein DnaA -
  H1W81_RS01275 (STHERMO_0257) spo0J 240598..241365 (-) 768 WP_011226714.1 ParB/RepB/Spo0J family partition protein Regulator
  H1W81_RS01280 (STHERMO_0258) htrA 241431..242666 (-) 1236 WP_011226713.1 S1C family serine protease Regulator
  H1W81_RS01285 (STHERMO_0259) rlmH 242871..243350 (+) 480 WP_011226712.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  H1W81_RS01290 (STHERMO_0260) - 243366..244049 (+) 684 WP_011226711.1 YoaK family protein -
  H1W81_RS01310 (STHERMO_0261) - 244594..247200 (-) 2607 WP_011226710.1 YfhO family protein -

Sequence

Protein


Download         Length: 411 a.a.        Molecular weight: 42859.14 Da        Isoelectric Point: 4.7061

>NTDB_id=1132315 H1W81_RS01280 WP_011226713.1 241431..242666(-) (htrA) [Streptococcus thermophilus isolate STH_CIRM_67]
MKKFNWKKIVAPIAMLIIGLLGGLLGAFILLTAAGVSFTNTTDTGVKTAKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGDSSDSSQENSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide


Download         Length: 1236 bp        

>NTDB_id=1132315 H1W81_RS01280 WP_011226713.1 241431..242666(-) (htrA) [Streptococcus thermophilus isolate STH_CIRM_67]
ATGAAAAAATTTAACTGGAAGAAAATAGTCGCGCCAATTGCAATGCTAATTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATACTGGAGTAAAAACGGCTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGTCTACAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCATGTTGTCGATGGGGCTAAAAAACTTGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAATTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGAATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(4-406)

PDZ domain (PDZ_2)

(307-402)

Trypsin-like peptidase domain (Trypsin_2)

(118-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.787

98.054

0.606
  htrA Streptococcus gordonii str. Challis substr. CH1

57.282

100

0.574
  htrA Streptococcus mitis NCTC 12261

53.79

99.513

0.535
  htrA Streptococcus pneumoniae TIGR4

53.545

99.513

0.533
  htrA Streptococcus pneumoniae D39

53.545

99.513

0.533
  htrA Streptococcus pneumoniae Rx1

53.545

99.513

0.533
  htrA Streptococcus pneumoniae R6

53.545

99.513

0.533

Multiple sequence alignment