Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   H1W94_RS07860 Genome accession   NZ_LR822041
Coordinates   1507402..1509555 (-) Length   717 a.a.
NCBI ID   WP_059257386.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1122     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1502402..1514555
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W94_RS07835 (STHERMO_1731) - 1503261..1503503 (-) 243 WP_011227518.1 Blp family class II bacteriocin -
  H1W94_RS07840 (STHERMO_1732) - 1503753..1504484 (+) 732 WP_002948869.1 LytR/AlgR family response regulator transcription factor -
  H1W94_RS09920 - 1505021..1505824 (+) 804 WP_224103634.1 ATP-binding protein -
  H1W94_RS07850 (STHERMO_1734) - 1505842..1506003 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  H1W94_RS07855 (STHERMO_1735) - 1506018..1507386 (-) 1369 Protein_1484 bacteriocin secretion accessory protein -
  H1W94_RS07860 (STHERMO_1738) comA/nlmT 1507402..1509555 (-) 2154 WP_059257386.1 peptide cleavage/export ABC transporter Regulator
  H1W94_RS07865 (STHERMO_1741) - 1510569..1512314 (-) 1746 WP_011226501.1 ABC transporter ATP-binding protein -
  H1W94_RS07870 (STHERMO_1742) - 1512307..1514064 (-) 1758 WP_011226502.1 ABC transporter ATP-binding protein -
  H1W94_RS09925 (STHERMO_1744) - 1514252..1514458 (-) 207 WP_002948879.1 hypothetical protein -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80569.46 Da        Isoelectric Point: 6.8330

>NTDB_id=1132079 H1W94_RS07860 WP_059257386.1 1507402..1509555(-) (comA/nlmT) [Streptococcus thermophilus isolate STH_CIRM_1122]
MFRFRRTFVPQIDMRNCGVAALALVAKYYGSDYSLAHLRELAKTNKEGTTALGLVEAAKKIGFETRAIKAEMSLFEMEDV
PYPFIAHVNKDGKLQHYYVIYKSTKDYLIIGDPDPSVKVTKMTKERFEKEWTGVTLFMGPEPSYKPHKDKKNGLWDFLPL
IFKQRSLIANIVFASLLVTLINILGSYYLQGILDEYVPNQMKSTLGIISIGLVVTYVLQQMMTFARDYLLTILSQRLTID
VILSYIRHIFELPMSFFATRRTGEVISRFSDANSIIDALASTILSLFLDFSIVIIVGGVLLIQNSNLFKLVLCSVPIYTL
IVFAFMKPFELMNHDVMQSNAMVNSAIIEDINGIETIKSLTSEEVCYQKIDGEFVDYLDNSFRLSKLSILQTSLKQGAQL
ILNVLILWTGAQLVMGNTISIGQLITFNMLLSYFTNPLENIINLQTKLQSAKVANTRLNEVYLIESEFGQSDDTYQEGIA
DGDITVTDLSYKYGFGRDTLTDVSLTIRQGEKISFVGVSGSGKTTLAKMLVNFYQPYKGHIDFNGQNISRIDKKTLRQHI
NYLPQQSYIFSGSVLENLTLGAARGITQADILKACEIAEIRQDIENMPMGFQTELSDGAGLSGGQKQRIALARALLTKSP
VLILDEATSGLDVLTEKQVIDNLLALKDKTIIFVAHRLSIAERTDRIVVIDQGRVVETGSHQDLMSYPGFYYQLFRK

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=1132079 H1W94_RS07860 WP_059257386.1 1507402..1509555(-) (comA/nlmT) [Streptococcus thermophilus isolate STH_CIRM_1122]
ATGTTTCGTTTTCGTAGGACTTTTGTCCCTCAAATAGACATGAGGAATTGTGGAGTTGCTGCCTTGGCATTAGTGGCCAA
GTACTATGGTTCAGATTATTCATTAGCACATCTGCGTGAGTTGGCGAAGACCAATAAAGAAGGGACAACTGCCTTAGGTC
TTGTAGAGGCTGCTAAAAAAATTGGCTTTGAAACGAGAGCTATAAAGGCTGAAATGTCGCTCTTTGAGATGGAAGATGTT
CCTTATCCTTTTATTGCTCATGTTAATAAAGATGGGAAGCTTCAACATTATTATGTTATTTATAAAAGCACCAAGGATTA
TCTGATAATTGGAGACCCTGATCCAAGTGTAAAAGTAACTAAAATGACTAAAGAGCGTTTTGAGAAAGAGTGGACAGGTG
TTACTCTTTTTATGGGACCGGAACCCAGTTATAAACCACATAAGGATAAGAAAAATGGACTCTGGGACTTTCTCCCTTTG
ATCTTTAAACAAAGGTCCTTGATAGCTAATATTGTCTTTGCCAGTCTCTTGGTTACTTTAATAAATATTTTAGGTTCCTA
TTATTTACAAGGTATTCTAGACGAATATGTCCCTAATCAAATGAAGTCTACCTTAGGAATTATCTCAATTGGATTAGTTG
TGACCTATGTTTTACAACAAATGATGACTTTTGCAAGAGATTATCTCTTAACCATACTGAGTCAGCGATTGACCATTGAC
GTTATCTTGTCCTACATACGACATATCTTTGAACTCCCAATGTCTTTTTTTGCCACAAGACGTACAGGGGAGGTTATCTC
ACGTTTTAGTGATGCTAACTCTATTATCGATGCTCTGGCTTCGACGATATTATCACTTTTCCTTGATTTCTCTATTGTGA
TTATCGTAGGAGGCGTGTTATTGATACAAAATAGCAATCTCTTCAAGCTAGTTCTTTGTTCGGTTCCAATTTATACCCTT
ATCGTCTTTGCCTTTATGAAACCTTTTGAGCTAATGAATCATGACGTCATGCAGAGTAATGCTATGGTTAATTCAGCCAT
CATTGAGGACATTAATGGGATTGAAACCATAAAGTCACTAACCAGCGAAGAAGTATGCTATCAAAAGATTGATGGTGAGT
TTGTTGACTATCTAGACAATTCTTTTCGCCTTTCTAAGTTATCTATACTACAAACATCATTGAAACAAGGTGCTCAACTT
ATTTTAAATGTACTTATCCTCTGGACAGGTGCTCAGTTGGTGATGGGAAATACCATTTCGATAGGACAATTGATTACTTT
TAATATGTTGCTTTCTTACTTCACGAATCCTTTGGAAAATATCATTAACCTGCAAACCAAGTTACAGTCTGCTAAGGTAG
CTAATACTAGGCTCAATGAGGTCTATCTGATTGAATCAGAGTTTGGACAAAGTGATGATACCTATCAAGAAGGCATTGCG
GATGGAGATATCACTGTTACGGATTTATCTTATAAATATGGTTTTGGTCGTGATACTTTGACTGATGTCAGTTTGACGAT
TAGACAAGGAGAAAAAATCAGTTTTGTTGGTGTCAGTGGATCTGGTAAGACTACTCTAGCTAAAATGTTGGTCAATTTTT
ATCAACCATATAAGGGGCACATAGATTTTAATGGTCAAAATATTAGTCGCATAGACAAGAAAACTCTTCGTCAACATATT
AACTATCTCCCTCAGCAATCCTATATATTTAGTGGTAGTGTTTTAGAAAATCTTACTTTAGGTGCAGCACGGGGTATTAC
GCAAGCTGATATTTTGAAAGCTTGTGAAATAGCAGAAATTCGTCAAGATATTGAAAACATGCCTATGGGGTTTCAGACAG
AGCTGTCTGATGGAGCAGGTCTGTCTGGAGGGCAAAAGCAACGTATCGCTTTGGCGCGTGCACTACTAACGAAATCTCCT
GTACTAATCTTAGATGAAGCAACTAGCGGATTGGATGTTTTGACAGAAAAGCAGGTTATTGATAACCTCCTAGCACTAAA
AGATAAAACGATCATCTTTGTAGCACACAGGCTTAGTATCGCTGAGCGGACCGACCGTATCGTAGTCATTGATCAGGGAC
GCGTAGTGGAGACAGGTTCTCATCAAGACCTGATGTCTTATCCAGGTTTCTATTATCAATTATTTAGAAAGTGA

Domains

Predicted by InterProScan.

ABC transporter transmembrane region (ABC_membrane)

(170-438)

ABC transporter (ABC_tran)

(500-649)

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

67.927

99.582

0.676
  comA Streptococcus mitis NCTC 12261

66.385

99.163

0.658
  comA Streptococcus pneumoniae Rx1

65.963

99.163

0.654
  comA Streptococcus pneumoniae D39

65.963

99.163

0.654
  comA Streptococcus pneumoniae R6

65.963

99.163

0.654
  comA Streptococcus mitis SK321

65.682

99.163

0.651
  comA Streptococcus pneumoniae TIGR4

65.541

99.163

0.65
  comA Streptococcus gordonii str. Challis substr. CH1

64.286

99.582

0.64

Multiple sequence alignment