Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   H1W80_RS06425 Genome accession   NZ_LR822040
Coordinates   1229352..1231223 (-) Length   623 a.a.
NCBI ID   WP_087010057.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1125     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1224352..1236223
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W80_RS06390 (STHERMO_1430) rimM 1224759..1225277 (-) 519 WP_011226286.1 ribosome maturation factor RimM -
  H1W80_RS06405 (STHERMO_1431) - 1225953..1226597 (-) 645 WP_002951384.1 response regulator transcription factor -
  H1W80_RS06410 (STHERMO_1432) - 1226587..1227597 (-) 1011 WP_180473276.1 sensor histidine kinase -
  H1W80_RS06415 (STHERMO_1433) liaF 1227594..1228292 (-) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  H1W80_RS09635 (STHERMO_1434) - 1228547..1228714 (-) 168 WP_224103618.1 potassium channel family protein -
  H1W80_RS06425 (STHERMO_1437) stkP/pknB 1229352..1231223 (-) 1872 WP_087010057.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  H1W80_RS06430 (STHERMO_1438) - 1231223..1231960 (-) 738 WP_002946881.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  H1W80_RS06435 (STHERMO_1439) rsmB 1232004..1233326 (-) 1323 WP_087010267.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  H1W80_RS06440 (STHERMO_1440) fmt 1233316..1234251 (-) 936 WP_002946883.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 623 a.a.        Molecular weight: 67781.63 Da        Isoelectric Point: 7.1313

>NTDB_id=1132005 H1W80_RS06425 WP_087010057.1 1229352..1231223(-) (stkP/pknB) [Streptococcus thermophilus isolate STH_CIRM_1125]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNESVAIKVLRTNYQTDQVAVARFQREARAMTELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKFIQDHAPLSNQDAVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGRAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPFDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHSRDSKVVFDDMTDAKTLPKVDSVPSVGPEKKISPKPSEPTPAP
SKQPREKASLSKKKKNLFSTLLKVLLGFVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKLESAGFKVGDVKEVEND
SVNKGKVIKTDPTAGTMRKEGASIDVYVSSGSKGFTLKNYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEGDNAKEGEILS
QSSEKNKSFNPKDSKAKIKFRVATPKTITMPDVTGLTVSTAVQTLNSKDISSSSIEYHDYNTGVKLDKSKVPSNTEVLYQ
DPQVGTAVDGTVILYVSVVTKSSSIQQSSSASTTQSPSSTSSSSESSTASSTETATEATHTEQ

Nucleotide


Download         Length: 1872 bp        

>NTDB_id=1132005 H1W80_RS06425 WP_087010057.1 1229352..1231223(-) (stkP/pknB) [Streptococcus thermophilus isolate STH_CIRM_1125]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAATCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAACGACCTGATTCTGGATAATGAAAGTGTAGCTATTAAGGTGCTACGTACCAATTATCAAACTGATCAGGTTG
CTGTGGCGCGTTTCCAGCGTGAAGCACGTGCCATGACTGAGCTTAGCCATCCGAATATCGTTGCGATTAGAGATATTGGT
GAAGAAGACGGTCAGCAGTTCTTGGTGATGGAGTATGTGGATGGTTCGGACTTGAAGAAATTCATTCAAGACCATGCACC
ATTGTCTAACCAAGATGCTGTGCGTATTATGGGGGAAGTCCTTTCCGCCATGACTCTTGCCCACCAAAAGGGTATTATTC
ACCGTGACCTTAAGCCACAGAACGTTCTATTAACTAAGGATGGTAGAGCTAAGGTTACAGACTTTGGTATCGCAGTAGCA
TTTGCTGAAACCAGCCTGACACAAACTAACTCAATGTTGGGGTCAGTCCATTATTTGTCACCAGAACAGGCACGTGGTTC
TAAAGCCACTATCCAAAGTGATATCTATGCTATGGGGATTATGCTCTTTGAAATGTTGACAGGGCATATCCCTTTTGATG
GCGATAGTGCAGTAACCATTGCACTTCAACATTTCCAAAAGCCCCTGCCATCGATTTTGGCTGAGAACCGTAACGTTCCT
CAAGCTTTAGAAAATGTTGTTATTAGAGCAACTGCTAAAAAGCTTGAAAATCGTTACAACAGCACTTTGGAAATGAGTCG
CGACCTAGTAACTAGTTTGCATCCTAGTCATAGTCGTGATTCTAAGGTAGTTTTTGATGACATGACGGATGCTAAGACCC
TGCCAAAGGTTGATTCAGTTCCATCAGTAGGTCCTGAGAAAAAGATTTCTCCTAAACCATCAGAGCCTACACCGGCTCCA
AGCAAACAACCGAGGGAAAAAGCTTCTCTATCTAAAAAAAAGAAAAATCTCTTTTCAACTCTACTCAAGGTTTTACTAGG
CTTCGTCTTTATAGGCATTATCATTTTTGCCTATCTTGTTTTTACCAATCCTGACAATGTCCAAGTACCAAATGTTGTAG
GTCAAGAGTTGTCAACAGCTCAGACGAAACTTGAAAGTGCAGGCTTTAAGGTTGGCGATGTTAAAGAAGTCGAAAATGAT
TCAGTCAATAAGGGCAAAGTTATCAAGACCGACCCTACAGCTGGGACAATGCGTAAAGAGGGAGCAAGCATTGATGTCTA
TGTTTCTTCTGGTAGCAAAGGTTTCACTCTGAAAAATTACAAGGGGAAAAATTATAAGGATGCCATTGAGGATTTAACCT
CGAATTATGGGGTTTCCGAGGATCAGATCGATATTCAACATGTCGAAGGCGATAATGCTAAAGAAGGCGAAATTCTATCT
CAAAGTTCGGAGAAAAACAAGTCCTTCAATCCTAAAGATAGTAAGGCAAAAATCAAGTTTCGTGTGGCAACTCCTAAGAC
TATAACTATGCCTGATGTGACTGGTTTAACTGTCTCGACAGCAGTCCAAACCTTGAATAGTAAAGACATTTCAAGTAGCA
GTATTGAGTATCATGACTATAATACTGGTGTTAAGTTGGATAAGAGTAAGGTACCTAGTAATACAGAGGTCCTTTATCAA
GATCCTCAAGTTGGTACTGCTGTTGATGGCACAGTGATTCTCTATGTTTCAGTCGTAACTAAGAGTTCAAGTATTCAACA
GTCAAGCTCAGCAAGTACGACACAATCGCCGTCATCTACAAGTTCTAGTTCTGAAAGTAGTACAGCTTCTAGTACCGAAA
CAGCTACAGAAGCTACTCACACAGAGCAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(508-577)

PASTA domain (PASTA)

(436-502)

PASTA domain (PASTA)

(367-429)

Protein kinase domain (Pkinase)

(12-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

90.361

93.258

0.843
  pknB Streptococcus mutans UA159

64.338

87.319

0.562
  stkP Streptococcus pneumoniae TIGR4

57.315

80.096

0.459
  stkP Streptococcus pneumoniae D39

57.114

80.096

0.457
  stkP Streptococcus pneumoniae R6

57.114

80.096

0.457
  stkP Streptococcus pneumoniae Rx1

56.914

80.096

0.456

Multiple sequence alignment