Detailed information NTG1131978

Bioinformatically predicted

Overview

• Name: mecA
• Type: Regulator
• Locus tag: H1W80_RS00985
• Genome accession: NZ_LR822040
• Coordinates: 170385..171134 (+)
• Length: 249 a.a.
• NCBI ID: WP_087009637.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1125
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 165385..176134

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W80_RS00955 (STHERMO_0176)	-	165961..166131 (+)	171	WP_011225360.1	hypothetical protein	-
H1W80_RS00960	-	166218..166325 (+)	108	WP_002949251.1	LPXTG cell wall anchor domain-containing protein	-
H1W80_RS00965 (STHERMO_0177)	-	166412..167152 (-)	741	WP_002949253.1	amino acid ABC transporter ATP-binding protein	-
H1W80_RS00970 (STHERMO_0178)	-	167152..168702 (-)	1551	WP_180473386.1	ABC transporter substrate-binding protein/permease	-
H1W80_RS00975 (STHERMO_0179)	-	168905..169759 (+)	855	WP_041828107.1	undecaprenyl-diphosphate phosphatase	-
H1W80_RS00980	-	169811..170119 (-)	309	WP_331251219.1	DUF3021 family protein	-
H1W80_RS00985 (STHERMO_0180)	mecA	170385..171134 (+)	750	WP_087009637.1	adaptor protein MecA	Regulator
H1W80_RS00990 (STHERMO_0181)	-	171138..172295 (+)	1158	WP_002947632.1	glycosyltransferase family 4 protein	-
H1W80_RS00995 (STHERMO_0182)	sufC	172456..173226 (+)	771	WP_002947634.1	Fe-S cluster assembly ATPase SufC	-
H1W80_RS01000 (STHERMO_0183)	sufD	173263..174525 (+)	1263	WP_002947640.1	Fe-S cluster assembly protein SufD	-
H1W80_RS01005 (STHERMO_0184)	-	174579..175811 (+)	1233	WP_002949261.1	cysteine desulfurase	-

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 29200.77 Da
• Isoelectric Point: 4.0930

>NTDB_id=1131978 H1W80_RS00985 WP_087009637.1 170385..171134(+) (mecA) [Streptococcus thermophilus isolate STH_CIRM_1125]
MEMKQINETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEEHDKTLKEVDETMTEPAKKVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSEFYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide

• Length: 750 bp

>NTDB_id=1131978 H1W80_RS00985 WP_087009637.1 170385..171134(+) (mecA) [Streptococcus thermophilus isolate STH_CIRM_1125]
ATGGAAATGAAACAAATAAACGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCATGATAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGAGCCGGCTAAGAAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAAGGTTCTGAATTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

• Negative regulator of genetic competence (MecA) (MecA) (1-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mecA	Streptococcus thermophilus LMD-9	99.197	100	0.992
mecA	Streptococcus thermophilus LMG 18311	99.197	100	0.992
mecA	Streptococcus mutans UA159	57.787	97.992	0.566
mecA	Streptococcus pneumoniae Rx1	46.586	100	0.466
mecA	Streptococcus pneumoniae D39	46.586	100	0.466
mecA	Streptococcus pneumoniae R6	46.586	100	0.466
mecA	Streptococcus pneumoniae TIGR4	46.586	100	0.466