Detailed information NTG1131970

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: H1W92_RS09510
• Genome accession: NZ_LR822039
• Coordinates: 1802064..1803299 (+)
• Length: 411 a.a.
• NCBI ID: WP_180475764.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1116
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1797064..1808299

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W92_RS09480 (STHERMO_2087)	-	1797530..1800136 (+)	2607	WP_011226710.1	YfhO family protein	-
H1W92_RS09500 (STHERMO_2088)	-	1800681..1801364 (-)	684	WP_011226711.1	YoaK family protein	-
H1W92_RS09505 (STHERMO_2089)	rlmH	1801380..1801859 (-)	480	WP_011226712.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
H1W92_RS09510 (STHERMO_2090)	htrA	1802064..1803299 (+)	1236	WP_180475764.1	S1C family serine protease	Regulator
H1W92_RS09515 (STHERMO_2091)	spo0J	1803365..1804132 (+)	768	WP_011226714.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42887.19 Da
• Isoelectric Point: 4.7061

>NTDB_id=1131970 H1W92_RS09510 WP_180475764.1 1802064..1803299(+) (htrA) [Streptococcus thermophilus isolate STH_CIRM_1116]
MKKFNWKKIVAPIAMLIIGLLGGLLGAFILLTAAGVSFTNTTDTGVKTAKTVYTNITDTTKAVKKVQNVVVSVINYQEGS
SSDSLNDLYGRIFGGGDSSDSSQENSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=1131970 H1W92_RS09510 WP_180475764.1 1802064..1803299(+) (htrA) [Streptococcus thermophilus isolate STH_CIRM_1116]
ATGAAAAAATTTAACTGGAAGAAAATAGTCGCGCCAATTGCAATGCTAATTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATACTGGAGTAAAAACGGCTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGTCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGTCTACAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCATGTTGTCGATGGGGCTAAAAAACTTGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAATTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGAATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (307-402)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• Peptidase family M50 (Peptidase_M50) (4-406)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.787	98.054	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.039	100	0.572
htrA	Streptococcus mitis NCTC 12261	53.545	99.513	0.533
htrA	Streptococcus pneumoniae TIGR4	53.301	99.513	0.53
htrA	Streptococcus pneumoniae D39	53.301	99.513	0.53
htrA	Streptococcus pneumoniae Rx1	53.301	99.513	0.53
htrA	Streptococcus pneumoniae R6	53.301	99.513	0.53