Detailed information NTG1131911

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: H1W87_RS09325
• Genome accession: NZ_LR822037
• Coordinates: 1779493..1780728 (+)
• Length: 411 a.a.
• NCBI ID: WP_180478317.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1121
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1774493..1785728

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W87_RS09295 (STHERMO_2084)	-	1774960..1777566 (+)	2607	WP_180478315.1	YfhO family protein	-
H1W87_RS09315 (STHERMO_2085)	-	1778111..1778794 (-)	684	WP_011226711.1	YoaK family protein	-
H1W87_RS09320 (STHERMO_2086)	rlmH	1778810..1779289 (-)	480	WP_002952297.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
H1W87_RS09325 (STHERMO_2087)	htrA	1779493..1780728 (+)	1236	WP_180478317.1	S1C family serine protease	Regulator
H1W87_RS09330 (STHERMO_2088)	spo0J	1780794..1781561 (+)	768	WP_002952299.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42886.21 Da
• Isoelectric Point: 4.7654

>NTDB_id=1131911 H1W87_RS09325 WP_180478317.1 1779493..1780728(+) (htrA) [Streptococcus thermophilus isolate STH_CIRM_1121]
MKKFNWKKIVAPIIMLVIGLLGGLLGAFILLTAAGVSFTNTTDTGVKTAKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGDSSDSSQENSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVNGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=1131911 H1W87_RS09325 WP_180478317.1 1779493..1780728(+) (htrA) [Streptococcus thermophilus isolate STH_CIRM_1121]
ATGAAAAAATTTAACTGGAAAAAAATAGTCGCGCCAATTATAATGCTAGTTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGAGTATCTTTTACCAATACAACAGATACTGGAGTAAAAACGGCTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGTCTGCAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTATATCGTAA
CCAATAACCACGTTGTCAATGGGGCTAAAAAACTTGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAATTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGGATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATTGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (4-406)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• PDZ domain (PDZ_2) (307-402)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	59.854	100	0.599
htrA	Streptococcus gordonii str. Challis substr. CH1	57.767	100	0.579
htrA	Streptococcus mitis NCTC 12261	54.279	99.513	0.54
htrA	Streptococcus pneumoniae TIGR4	54.034	99.513	0.538
htrA	Streptococcus pneumoniae D39	54.034	99.513	0.538
htrA	Streptococcus pneumoniae Rx1	54.034	99.513	0.538
htrA	Streptococcus pneumoniae R6	54.034	99.513	0.538