Detailed information NTG1131611

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: H1W91_RS09660
• Genome accession: NZ_LR822032
• Coordinates: 1844925..1846160 (+)
• Length: 411 a.a.
• NCBI ID: WP_180477210.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1050
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1839925..1851160

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W91_RS09630 (STHERMO_2133)	-	1840392..1842998 (+)	2607	WP_180477209.1	YfhO family protein	-
H1W91_RS09650 (STHERMO_2134)	-	1843542..1844225 (-)	684	WP_096811735.1	YoaK family protein	-
H1W91_RS09655 (STHERMO_2135)	rlmH	1844241..1844720 (-)	480	WP_002952297.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
H1W91_RS09660 (STHERMO_2136)	htrA	1844925..1846160 (+)	1236	WP_180477210.1	S1C family serine protease	Regulator
H1W91_RS09665 (STHERMO_2137)	spo0J	1846226..1846993 (+)	768	WP_180477211.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42858.15 Da
• Isoelectric Point: 4.7654

>NTDB_id=1131611 H1W91_RS09660 WP_180477210.1 1844925..1846160(+) (htrA) [Streptococcus thermophilus isolate STH_CIRM_1050]
MKKFNWKKIVAPIAMLIIGLLGGLLGAFILLTAAGVSFTNTTDTGVKTAKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGDSSDSSQENSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVNGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=1131611 H1W91_RS09660 WP_180477210.1 1844925..1846160(+) (htrA) [Streptococcus thermophilus isolate STH_CIRM_1050]
ATGAAAAAATTTAACTGGAAGAAAATAGTCGCGCCAATTGCAATGCTAATTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATACTGGAGTAAAAACGGCTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGTCTGCAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTATATCGTAA
CCAATAACCACGTTGTCAATGGGGCTAAAAAACTTGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAATTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGGATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• PDZ domain (PDZ_2) (307-402)

• Peptidase family M50 (Peptidase_M50) (4-406)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.787	98.054	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.524	100	0.577
htrA	Streptococcus mitis NCTC 12261	54.034	99.513	0.538
htrA	Streptococcus pneumoniae TIGR4	53.79	99.513	0.535
htrA	Streptococcus pneumoniae D39	53.79	99.513	0.535
htrA	Streptococcus pneumoniae Rx1	53.79	99.513	0.535
htrA	Streptococcus pneumoniae R6	53.79	99.513	0.535