Detailed information NTG1131559

Bioinformatically predicted

Overview

• Name: mecA
• Type: Regulator
• Locus tag: H1W91_RS01025
• Genome accession: NZ_LR822032
• Coordinates: 174177..174926 (+)
• Length: 249 a.a.
• NCBI ID: WP_022096529.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1050
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 169177..179926

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W91_RS00995 (STHERMO_0181)	-	169752..169922 (+)	171	WP_180476706.1	hypothetical protein	-
H1W91_RS01000	-	170009..170116 (+)	108	WP_002949251.1	LPXTG cell wall anchor domain-containing protein	-
H1W91_RS01005 (STHERMO_0182)	-	170203..170943 (-)	741	WP_002949253.1	amino acid ABC transporter ATP-binding protein	-
H1W91_RS01010 (STHERMO_0183)	-	170943..172493 (-)	1551	WP_022096528.1	ABC transporter substrate-binding protein/permease	-
H1W91_RS01015 (STHERMO_0184)	-	172696..173550 (+)	855	WP_180476708.1	undecaprenyl-diphosphate phosphatase	-
H1W91_RS01020	-	173696..173911 (-)	216	WP_011226805.1	DUF3021 family protein	-
H1W91_RS01025 (STHERMO_0185)	mecA	174177..174926 (+)	750	WP_022096529.1	adaptor protein MecA	Regulator
H1W91_RS01030 (STHERMO_0186)	-	174930..176087 (+)	1158	WP_002947632.1	glycosyltransferase family 4 protein	-
H1W91_RS01035 (STHERMO_0187)	sufC	176252..177022 (+)	771	WP_002947634.1	Fe-S cluster assembly ATPase SufC	-
H1W91_RS01040 (STHERMO_0188)	sufD	177059..178321 (+)	1263	WP_180476710.1	Fe-S cluster assembly protein SufD	-
H1W91_RS01045 (STHERMO_0189)	-	178375..179607 (+)	1233	WP_022096530.1	cysteine desulfurase	-

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 29156.76 Da
• Isoelectric Point: 4.1121

>NTDB_id=1131559 H1W91_RS01025 WP_022096529.1 174177..174926(+) (mecA) [Streptococcus thermophilus isolate STH_CIRM_1050]
MEMKQINETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEALDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEEHDKTLKEVDETMTEPAKKVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSEFYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide

• Length: 750 bp

>NTDB_id=1131559 H1W91_RS01025 WP_022096529.1 174177..174926(+) (mecA) [Streptococcus thermophilus isolate STH_CIRM_1050]
ATGGAAATGAAACAAATAAACGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAATT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAATCAGATCTT
AAGGAAGCCCTTGATTTCAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCATGATAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGAGCCGGCTAAGAAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAGGGTTCTGAATTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

• Negative regulator of genetic competence (MecA) (MecA) (1-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mecA	Streptococcus thermophilus LMG 18311	99.598	100	0.996
mecA	Streptococcus thermophilus LMD-9	98.795	100	0.988
mecA	Streptococcus mutans UA159	57.787	97.992	0.566
mecA	Streptococcus pneumoniae Rx1	46.586	100	0.466
mecA	Streptococcus pneumoniae D39	46.586	100	0.466
mecA	Streptococcus pneumoniae R6	46.586	100	0.466
mecA	Streptococcus pneumoniae TIGR4	46.586	100	0.466