Detailed information NTG1131551

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: H1W74_RS09385
• Genome accession: NZ_LR822031
• Coordinates: 1812591..1813826 (+)
• Length: 411 a.a.
• NCBI ID: WP_022096467.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1047
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1807591..1818826

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W74_RS09355 (STHERMO_2124)	-	1808058..1810664 (+)	2607	WP_002946816.1	YfhO family protein	-
H1W74_RS09375 (STHERMO_2125)	-	1811208..1811891 (-)	684	WP_180473154.1	YoaK family protein	-
H1W74_RS09380 (STHERMO_2126)	rlmH	1811907..1812386 (-)	480	WP_180473206.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
H1W74_RS09385 (STHERMO_2127)	htrA	1812591..1813826 (+)	1236	WP_022096467.1	S1C family serine protease	Regulator
H1W74_RS09390 (STHERMO_2128)	spo0J	1813892..1814659 (+)	768	WP_002948582.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42872.14 Da
• Isoelectric Point: 4.7061

>NTDB_id=1131551 H1W74_RS09385 WP_022096467.1 1812591..1813826(+) (htrA) [Streptococcus thermophilus isolate STH_CIRM_1047]
MKKFNWKKIVAPIAMLIIGLLGGLLGAFILLTAAGVSFTNTTDNGVKTAKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGDSSDSSQENSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=1131551 H1W74_RS09385 WP_022096467.1 1812591..1813826(+) (htrA) [Streptococcus thermophilus isolate STH_CIRM_1047]
ATGAAAAAATTTAACTGGAAGAAAATAGTCGCGCCAATTGCAATGCTAATTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATAATGGAGTAAAAACGGCTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAAAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCACTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGTCTACAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCACGTTGTCGATGGGGCTAAAAAACTTGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAATTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGGATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATTGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (5-406)

• PDZ domain (PDZ_2) (307-402)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.596	97.567	0.601
htrA	Streptococcus gordonii str. Challis substr. CH1	57.524	100	0.577
htrA	Streptococcus mitis NCTC 12261	54.034	99.513	0.538
htrA	Streptococcus pneumoniae TIGR4	53.79	99.513	0.535
htrA	Streptococcus pneumoniae D39	53.79	99.513	0.535
htrA	Streptococcus pneumoniae Rx1	53.79	99.513	0.535
htrA	Streptococcus pneumoniae R6	53.79	99.513	0.535