Detailed information NTG1131493

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: H1W95_RS09775
• Genome accession: NZ_LR822030
• Coordinates: 1887491..1888726 (+)
• Length: 411 a.a.
• NCBI ID: WP_180483428.1
• Uniprot ID: A0AAU9H919
• Organism: Streptococcus thermophilus isolate STH_CIRM_1046
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1882491..1893726

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W95_RS09745 (STHERMO_2204)	-	1882959..1885565 (+)	2607	WP_041827400.1	YfhO family protein	-
H1W95_RS09765 (STHERMO_2205)	-	1886108..1886791 (-)	684	WP_011226711.1	YoaK family protein	-
H1W95_RS09770 (STHERMO_2206)	rlmH	1886807..1887286 (-)	480	WP_002952297.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
H1W95_RS09775 (STHERMO_2207)	htrA	1887491..1888726 (+)	1236	WP_180483428.1	S1C family serine protease	Regulator
H1W95_RS09780 (STHERMO_2208)	spo0J	1888792..1889559 (+)	768	WP_002952299.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42927.30 Da
• Isoelectric Point: 4.7061

>NTDB_id=1131493 H1W95_RS09775 WP_180483428.1 1887491..1888726(+) (htrA) [Streptococcus thermophilus isolate STH_CIRM_1046]
MKKFNWKKIVVPIAMLIIGLLGGLLGAFILLTAAGVSFTNTTDTGVKTVKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGDSSDSSQENSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVIEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=1131493 H1W95_RS09775 WP_180483428.1 1887491..1888726(+) (htrA) [Streptococcus thermophilus isolate STH_CIRM_1046]
ATGAAAAAATTTAACTGGAAGAAAATAGTCGTGCCAATTGCAATGCTAATTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATACTGGAGTAAAAACGGTTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGTCTGCAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCACGTTGTCGATGGGGCTAAAAAACTTGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAATAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGGATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• PDZ domain (PDZ_2) (307-402)

• Peptidase family M50 (Peptidase_M50) (6-406)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	59.854	100	0.599
htrA	Streptococcus gordonii str. Challis substr. CH1	57.143	98.783	0.564
htrA	Streptococcus mitis NCTC 12261	53.545	99.513	0.533
htrA	Streptococcus pneumoniae TIGR4	53.301	99.513	0.53
htrA	Streptococcus pneumoniae D39	53.301	99.513	0.53
htrA	Streptococcus pneumoniae Rx1	53.301	99.513	0.53
htrA	Streptococcus pneumoniae R6	53.301	99.513	0.53