Detailed information NTG1131349

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: H1X63_RS05640
• Genome accession: NZ_LR822027
• Coordinates: 1069899..1070606 (-)
• Length: 235 a.a.
• NCBI ID: WP_179971935.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_998
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1064899..1075606

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1X63_RS05615 (STHERMO_1214)	yidA	1065249..1066058 (+)	810	WP_179971931.1	sugar-phosphatase	-
H1X63_RS05620 (STHERMO_1215)	-	1066060..1067274 (+)	1215	WP_179971932.1	aminoacyltransferase	-
H1X63_RS05625	-	1067327..1067688 (-)	362	Protein_1051	YbaN family protein	-
H1X63_RS05630 (STHERMO_1216)	vicX	1067748..1068560 (-)	813	WP_179971933.1	MBL fold metallo-hydrolase	Regulator
H1X63_RS05635 (STHERMO_1217)	vicK	1068566..1069906 (-)	1341	WP_179971934.1	cell wall metabolism sensor histidine kinase VicK	Regulator
H1X63_RS05640 (STHERMO_1218)	vicR	1069899..1070606 (-)	708	WP_179971935.1	response regulator YycF	Regulator
H1X63_RS05645 (STHERMO_1220)	-	1071130..1071897 (+)	768	WP_179973337.1	amino acid ABC transporter ATP-binding protein	-
H1X63_RS05650 (STHERMO_1221)	-	1071909..1072742 (+)	834	WP_179971937.1	transporter substrate-binding domain-containing protein	-
H1X63_RS05655 (STHERMO_1222)	-	1072760..1073458 (+)	699	WP_179971938.1	amino acid ABC transporter permease	-
H1X63_RS05660 (STHERMO_1223)	-	1073470..1074120 (+)	651	WP_179971939.1	amino acid ABC transporter permease	-
H1X63_RS05665 (STHERMO_1225)	-	1074184..1075440 (-)	1257	WP_179971940.1	ISL3 family transposase	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27205.13 Da
• Isoelectric Point: 4.8347

>NTDB_id=1131349 H1X63_RS05640 WP_179971935.1 1069899..1070606(-) (vicR) [Streptococcus thermophilus isolate STH_CIRM_998]
MKKILVVDDERPISDIIKFNLTKEGYEVVTTFDGREALEQFEAEKPDLVILDLMLPELDGLEVVKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEDNSNFGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=1131349 H1X63_RS05640 WP_179971935.1 1069899..1070606(-) (vicR) [Streptococcus thermophilus isolate STH_CIRM_998]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGACCTTTGATGGTCGTGAAGCTTTGGAACAATTTGAAGCTGAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGTCAAGGAAATCCGTAAAACGAGCCACACACCAATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTAACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACAATTGAAACTGCAGTAGAAGATAACTCTAACTTTGGCA
AGCAAGAAATTTCAATTGGTGAGTTGATTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAGATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	84.255	100	0.843
micA	Streptococcus pneumoniae Cp1015	78.97	99.149	0.783
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.022	98.298	0.443
covR	Streptococcus salivarius strain HSISS4	44.444	99.574	0.443
scnR	Streptococcus mutans UA159	38.983	100	0.391